Q9Y5A7: NEDD8 ultimate buster 1

General Information

Protein names	- NEDD8 ultimate buster 1 - Negative regulator of ubiquitin-like proteins 1 - Renal carcinoma antigen NY-REN-18
Gene names	NUB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y5A7

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAQKKYLQAK LTQFLREDRI QLWKPPYTDE NKKVGLALKD LAKQYSDRLE CCENEVEKVI
        70         80         90        100        110        120
EEIRCKAIER GTGNDNYRTT GIATIEVFLP PRLKKDRKNL LETRLHITGR ELRSKIAETF
       130        140        150        160        170        180
GLQENYIKIV INKKQLQLGK TLEEQGVAHN VKAMVLELKQ SEEDARKNFQ LEEEEQNEAK
       190        200        210        220        230        240
LKEKQIQRTK RGLEILAKRA AETVVDPEMT PYLDIANQTG RSIRIPPSER KALMLAMGYH
       250        260        270        280        290        300
EKGRAFLKRK EYGIALPCLL DADKYFCECC RELLDTVDNY AVLQLDIVWC YFRLEQLECL
       310        320        330        340        350        360
DDAEKKLNLA QKCFKNCYGE NHQRLVHIKG NCGKEKVLFL RLYLLQGIRN YHSGNDVEAY
       370        380        390        400        410        420
EYLNKARQLF KELYIDPSKV DNLLQLGFTA QEARLGLRAC DGNVDHAATH ITNRREELAQ
       430        440        450        460        470        480
IRKEEKEKKR RRLENIRFLK GMGYSTHAAQ QVLHAASGNL DEALKILLSN PQMWWLNDSN
       490        500        510        520        530        540
PETDNRQESP SQENIDRLVY MGFDALVAEA ALRVFRGNVQ LAAQTLAHNG GSLPPELPLS
       550        560        570        580        590        600
PEDSLSPPAT SPSDSAGTSS ASTDEDMETE AVNEILEDIP EHEEDYLDST LEDEEIIIAE
       610
YLSYVENRKS ATKKN

Isoforms

- Isoform 2 of NEDD8 ultimate buster 1

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y5A7-1-unknown	MAQKKY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y5A7-1-unknown	MAQKKY...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83489
Q9Y5A7-2-acetylation	AQKKYL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y5A7-2-acetylation	AQKKYL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y5A7-2-acetylation	AQKKYL...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162764

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ATKKN	615		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATKKN	615		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...ATKKN	615	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ATKKN	615	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt79107
...ATKKN	615		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATKKN	615		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)