TopFIND 4.0

Q9Y616: Interleukin-1 receptor-associated kinase 3

General Information

Protein names
- Interleukin-1 receptor-associated kinase 3
- IRAK-3
- 2.7.11.1
- IL-1 receptor-associated kinase M
- IRAK-M
Gene names IRAK3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y616

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGNCGARGA LSAHTLLFDL PPALLGELCA VLDSCDGALG WRGLAERLSS SWLDVRHIEK 
        70         80         90        100        110        120 
YVDQGKSGTR ELLWSWAQKN KTIGDLLQVL QEMGHRRAIH LITNYGAVLS PSEKSYQEGG 
       130        140        150        160        170        180 
FPNILFKETA NVTVDNVLIP EHNEKGILLK SSISFQNIIE GTRNFHKDFL IGEGEIFEVY 
       190        200        210        220        230        240 
RVEIQNLTYA VKLFKQEKKM QCKKHWKRFL SELEVLLLFH HPNILELAAY FTETEKFCLI 
       250        260        270        280        290        300 
YPYMRNGTLF DRLQCVGDTA PLPWHIRIGI LIGISKAIHY LHNVQPCSVI CGSISSANIL 
       310        320        330        340        350        360 
LDDQFQPKLT DFAMAHFRSH LEHQSCTINM TSSSSKHLWY MPEEYIRQGK LSIKTDVYSF 
       370        380        390        400        410        420 
GIVIMEVLTG CRVVLDDPKH IQLRDLLREL MEKRGLDSCL SFLDKKVPPC PRNFSAKLFC 
       430        440        450        460        470        480 
LAGRCAATRA KLRPSMDEVL NTLESTQASL YFAEDPPTSL KSFRCPSPLF LENVPSIPVE 
       490        500        510        520        530        540 
DDESQNNNLL PSDEGLRIDR MTQKTPFECS QSEVMFLSLD KKPESKRNEE ACNMPSSSCE 
       550        560        570        580        590    
ESWFPKYIVP SQDLRPYKVN IDPSSEAPGH SCRSRPVESS CSSKFSWDEY EQYKKE

Isoforms

- Isoform 2 of Interleukin-1 receptor-associated kinase 3

Sequence View

        10         20         30         40         50         60 
MAGNCGARGA LSAHTLLFDL PPALLGELCA VLDSCDGALG WRGLAERLSS SWLDVRHIEK 
        70         80         90        100        110        120 
YVDQGKSGTR ELLWSWAQKN KTIGDLLQVL QEMGHRRAIH LITNYGAVLS PSEKSYQEGG 
       130        140        150        160        170        180 
FPNILFKETA NVTVDNVLIP EHNEKGILLK SSISFQNIIE GTRNFHKDFL IGEGEIFEVY 
       190        200        210        220        230        240 
RVEIQNLTYA VKLFKQEKKM QCKKHWKRFL SELEVLLLFH HPNILELAAY FTETEKFCLI 
       250        260        270        280        290        300 
YPYMRNGTLF DRLQCVGDTA PLPWHIRIGI LIGISKAIHY LHNVQPCSVI CGSISSANIL 
       310        320        330        340        350        360 
LDDQFQPKLT DFAMAHFRSH LEHQSCTINM TSSSSKHLWY MPEEYIRQGK LSIKTDVYSF 
       370        380        390        400        410        420 
GIVIMEVLTG CRVVLDDPKH IQLRDLLREL MEKRGLDSCL SFLDKKVPPC PRNFSAKLFC 
       430        440        450        460        470        480 
LAGRCAATRA KLRPSMDEVL NTLESTQASL YFAEDPPTSL KSFRCPSPLF LENVPSIPVE 
       490        500        510        520        530        540 
DDESQNNNLL PSDEGLRIDR MTQKTPFECS QSEVMFLSLD KKPESKRNEE ACNMPSSSCE 
       550        560        570        580        590    
ESWFPKYIVP SQDLRPYKVN IDPSSEAPGH SCRSRPVESS CSSKFSWDEY EQYKKE



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Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y616-1-unknown MAGNCG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y616-1-unknown MAGNCG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78068

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QYKKE 596 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QYKKE 596 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73686

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)