Q9Y6D9: Mitotic spindle assembly checkpoint protein MAD1

General Information

Protein names	- Mitotic spindle assembly checkpoint protein MAD1 - Mitotic arrest deficient 1-like protein 1 - MAD1-like protein 1 - Mitotic checkpoint MAD1 protein homolog - HsMAD1 - hMAD1 - Tax-binding protein 181
Gene names	MAD1L1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6D9

5 N-termini

10 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEDLGENTMV LSTLRSLNNF ISQRVEGGSG LDISTSAPGS LQMQYQQSMQ LEERAEQIRS
        70         80         90        100        110        120
KSHLIQVERE KMQMELSHKR ARVELERAAS TSARNYEREV DRNQELLTRI RQLQEREAGA
       130        140        150        160        170        180
EEKMQEQLER NRQCQQNLDA ASKRLREKED SLAQAGETIN ALKGRISELQ WSVMDQEMRV
       190        200        210        220        230        240
KRLESEKQEL QEQLDLQHKK CQEANQKIQE LQASQEARAD HEQQIKDLEQ KLSLQEQDAA
       250        260        270        280        290        300
IVKNMKSELV RLPRLERELK QLREESAHLR EMRETNGLLQ EELEGLQRKL GRQEKMQETL
       310        320        330        340        350        360
VGLELENERL LAKLQSWERL DQTMGLSIRT PEDLSRFVVE LQQRELALKD KNSAVTSSAR
       370        380        390        400        410        420
GLEKARQQLQ EELRQVSGQL LEERKKRETH EALARRLQKR VLLLTKERDG MRAILGSYDS
       430        440        450        460        470        480
ELTPAEYSPQ LTRRMREAED MVQKVHSHSA EMEAQLSQAL EELGGQKQRA DMLEMELKML
       490        500        510        520        530        540
KSQSSSAEQS FLFSREEADT LRLKVEELEG ERSRLEEEKR MLEAQLERRA LQGDYDQSRT
       550        560        570        580        590        600
KVLHMSLNPT SVARQRLRED HSQLQAECER LRGLLRAMER GGTVPADLEA AAASLPSSKE
       610        620        630        640        650        660
VAELKKQVES AELKNQRLKE VFQTKIQEFR KACYTLTGYQ IDITTENQYR LTSLYAEHPG
       670        680        690        700        710
DCLIFKATSP SGSKMQLLET EFSHTVGELI EVHLRRQDSI PAFLSSLTLE LFSRQTVA

Isoforms

- Isoform 2 of Mitotic spindle assembly checkpoint protein MAD1

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 10 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y6D9-1-Acetylation	MEDLGE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y6D9-1-Acetylation	MEDLGE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y6D9-1-Acetylation	MEDLGE...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9Y6D9-1-Acetylation	MEDLGE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y6D9-72-unknown	MQMELS...	72		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000413139
Q9Y6D9-124-unknown	MQEQLE...	124		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401901
Q9Y6D9-411-unknown	MRAILG...	411		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000393037
Q9Y6D9-411-unknown	MRAILG...	411		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000397417
Q9Y6D9-545-unknown	MSLNPT...	545		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000394069

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AQAGET	157	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395457
...KQELQE	191	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390099
...QEELEG	284	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413139
...MGLSIR	328	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401901
...SHSAEM	451	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397417
...SAEQSF	490	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393037
...RRALQG	532	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000414877
...CLIFKA	666	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394069
...LFSRQT	715	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394886
...RQTVA	718	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)