Q9Y6E7: NAD-dependent protein lipoamidase sirtuin-4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000303|PubMed:25525879}
| Protein names | - NAD-dependent protein lipoamidase sirtuin-4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000303|PubMed:25525879} - 3.5.1.- {ECO:0000255|HAMAP-Rule:MF_03161, ECO:0000305|PubMed:25525879} - NAD-dependent ADP-ribosyltransferase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161} - 2.4.2.- {ECO:0000255|HAMAP-Rule:MF_03161} - NAD-dependent protein deacetylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161} - 3.5.1.- {ECO:0000255|HAMAP-Rule:MF_03161} - Regulatory protein SIR2 homolog 4 {ECO:0000255|HAMAP-Rule:MF_03161} - SIR2-like protein 4 {ECO:0000255|HAMAP-Rule:MF_03161} |
|---|---|
| Gene names | SIRT4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9Y6E7 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKMSFALTFR SAKGRWIANP SQPCSKASIG LFVPASPPLD PEKVKELQRF ITLSKRLLVM
70 80 90 100 110 120
TGAGISTESG IPDYRSEKVG LYARTDRRPI QHGDFVRSAP IRQRYWARNF VGWPQFSSHQ
130 140 150 160 170 180
PNPAHWALST WEKLGKLYWL VTQNVDALHT KAGSRRLTEL HGCMDRVLCL DCGEQTPRGV
190 200 210 220 230 240
LQERFQVLNP TWSAEAHGLA PDGDVFLSEE QVRSFQVPTC VQCGGHLKPD VVFFGDTVNP
250 260 270 280 290 300
DKVDFVHKRV KEADSLLVVG SSLQVYSGYR FILTAWEKKL PIAILNIGPT RSDDLACLKL
310
NSRCGELLPL IDPC
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9Y6E7-29-unknown | IGLFVP... | 29 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9Y6E7-60-unknown | MTGAGI... | 60 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000444838 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...HGCMDR | 165 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000444838 | |||
| ...LIDPC | 314 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|