TopFIND 4.0

Q9Y6I4: Ubiquitin carboxyl-terminal hydrolase 3

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase 3
- 3.4.19.12
- Deubiquitinating enzyme 3
- Ubiquitin thioesterase 3
- Ubiquitin-specific-processing protease 3
Gene names USP3
Organism Homo sapiens
Protease Family
Protease ID C19.026
Chromosome location
UniProt ID Q9Y6I4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MECPHLSSSV CIAPDSAKFP NGSPSSWCCS VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH 
        70         80         90        100        110        120 
YEDAQVPLTN HKKSEKQDKV QHTVCMDCSS YSTYCYRCDD FVVNDTKLGL VQKVREHLQN 
       130        140        150        160        170        180 
LENSAFTADR HKKRKLLENS TLNSKLLKVN GSTTAICATG LRNLGNTCFM NAILQSLSNI 
       190        200        210        220        230        240 
EQFCCYFKEL PAVELRNGKT AGRRTYHTRS QGDNNVSLVE EFRKTLCALW QGSQTAFSPE 
       250        260        270        280        290        300 
SLFYVVWKIM PNFRGYQQQD AHEFMRYLLD HLHLELQGGF NGVSRSAILQ ENSTLSASNK 
       310        320        330        340        350        360 
CCINGASTVV TAIFGGILQN EVNCLICGTE SRKFDPFLDL SLDIPSQFRS KRSKNQENGP 
       370        380        390        400        410        420 
VCSLRDCLRS FTDLEELDET ELYMCHKCKK KQKSTKKFWI QKLPKVLCLH LKRFHWTAYL 
       430        440        450        460        470        480 
RNKVDTYVEF PLRGLDMKCY LLEPENSGPE SCLYDLAAVV VHHGSGVGSG HYTAYATHEG 
       490        500        510        520    
RWFHFNDSTV TLTDEETVVK AKAYILFYVE HQAKAGSDKL 

Isoforms

- Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 3

Sequence View

        10         20         30         40         50         60 
MECPHLSSSV CIAPDSAKFP NGSPSSWCCS VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH 
        70         80         90        100        110        120 
YEDAQVPLTN HKKSEKQDKV QHTVCMDCSS YSTYCYRCDD FVVNDTKLGL VQKVREHLQN 
       130        140        150        160        170        180 
LENSAFTADR HKKRKLLENS TLNSKLLKVN GSTTAICATG LRNLGNTCFM NAILQSLSNI 
       190        200        210        220        230        240 
EQFCCYFKEL PAVELRNGKT AGRRTYHTRS QGDNNVSLVE EFRKTLCALW QGSQTAFSPE 
       250        260        270        280        290        300 
SLFYVVWKIM PNFRGYQQQD AHEFMRYLLD HLHLELQGGF NGVSRSAILQ ENSTLSASNK 
       310        320        330        340        350        360 
CCINGASTVV TAIFGGILQN EVNCLICGTE SRKFDPFLDL SLDIPSQFRS KRSKNQENGP 
       370        380        390        400        410        420 
VCSLRDCLRS FTDLEELDET ELYMCHKCKK KQKSTKKFWI QKLPKVLCLH LKRFHWTAYL 
       430        440        450        460        470        480 
RNKVDTYVEF PLRGLDMKCY LLEPENSGPE SCLYDLAAVV VHHGSGVGSG HYTAYATHEG 
       490        500        510        520    
RWFHFNDSTV TLTDEETVVK AKAYILFYVE HQAKAGSDKL 



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y6I4-1-Acetylation MECPHL... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y6I4-1-Acetylation MECPHL... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt96878
    Q9Y6I4-1-unknown MECPHL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93693

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GSDKL 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GSDKL 520 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89311

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)