Q9Y6Q6: Tumor necrosis factor receptor superfamily member 11A

General Information

Protein names	- Tumor necrosis factor receptor superfamily member 11A - Osteoclast differentiation factor receptor - ODFR - Receptor activator of NF-KB - CD265
Gene names	TNFRSF11A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6Q6

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Tumor necrosis factor receptor superfamily member 11A - Isoform 3 of Tumor necrosis factor receptor superfamily member 11A - Isoform 4 of Tumor necrosis factor receptor superfamily member 11A - Isoform 5 of Tumor necrosis factor receptor superfamily member 11A - Isoform RANK-e5a of Tumor necrosis factor receptor superfamily member 11A

Sequence View

        10         20         30         40         50         60
MAPRARRRRP LFALLLLCAL LARLQVALQI APPCTSEKHY EHLGRCCNKC EPGKYMSSKC
        70         80         90        100        110        120
TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW
       130        140        150        160        170        180
SQDCECCRRN TECAPGLGAQ HPLQLNKDTV CKPCLAGYFS DAFSSTDKCR PWTNCTFLGK
       190        200        210        220        230        240
RVEHHGTEKS DAVCSSSLPA RKPPNEPHVY LPGLIILLLF ASVALVAAII FGVCYRKKGK
       250        260        270        280        290        300
ALTANLWHWI NEACGRLSGD KESSGDSCVS THTANFGQQG ACEGVLLLTL EEKTFPEDMC
       310        320        330        340        350        360
YPDQGGVCQG TCVGGGPYAQ GEDARMLSLV SKTEIEEDSF RQMPTEDEYM DRPSQPTDQL
       370        380        390        400        410        420
LFLTEPGSKS TPPFSEPLEV GENDSLSQCF TGTQSTVGSE SCNCTEPLCR TDWTPMSSEN
       430        440        450        460        470        480
YLQKEVDSGH CPHWAASPSP NWADVCTGCR NPPGEDCEPL VGSPKRGPLP QCAYGMGLPP
       490        500        510        520        530        540
EEEASRTEAR DQPEDGADGR LPSSARAGAG SGSSPGGQSP ASGNVTGNSN STFISSGQVM
       550        560        570        580        590        600
NFKGDIIVVY VSQTSQEGAA AAAEPMGRPV QEETLARRDS FAGNGPRFPD PCGGPEGLRE
       610
PEKASRPVQE QGGAKA         10         20         30         40         50         60
MAPRARRRRP LFALLLLCAL LARLQVALQI APPCTSEKHY EHLGRCCNKC EPGKYMSSKC
        70         80         90        100        110        120
TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW
       130        140        150        160        170        180
SQDCECCRRN TECAPGLGAQ HPLQLNKDTV CKPCLAGYFS DAFSSTDKCR PWTNCTFLGK
       190        200        210        220        230        240
RVEHHGTEKS DAVCSSSLPA RKPPNEPHVY LPGLIILLLF ASVALVAAII FGVCYRKKGK
       250        260        270        280        290        300
ALTANLWHWI NEACGRLSGD KESSGDSCVS THTANFGQQG ACEGVLLLTL EEKTFPEDMC
       310        320        330        340        350        360
YPDQGGVCQG TCVGGGPYAQ GEDARMLSLV SKTEIEEDSF RQMPTEDEYM DRPSQPTDQL
       370        380        390        400        410        420
LFLTEPGSKS TPPFSEPLEV GENDSLSQCF TGTQSTVGSE SCNCTEPLCR TDWTPMSSEN
       430        440        450        460        470        480
YLQKEVDSGH CPHWAASPSP NWADVCTGCR NPPGEDCEPL VGSPKRGPLP QCAYGMGLPP
       490        500        510        520        530        540
EEEASRTEAR DQPEDGADGR LPSSARAGAG SGSSPGGQSP ASGNVTGNSN STFISSGQVM
       550        560        570        580        590        600
NFKGDIIVVY VSQTSQEGAA AAAEPMGRPV QEETLARRDS FAGNGPRFPD PCGGPEGLRE
       610
PEKASRPVQE QGGAKA         10         20         30         40         50         60
MAPRARRRRP LFALLLLCAL LARLQVALQI APPCTSEKHY EHLGRCCNKC EPGKYMSSKC
        70         80         90        100        110        120
TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW
       130        140        150        160        170        180
SQDCECCRRN TECAPGLGAQ HPLQLNKDTV CKPCLAGYFS DAFSSTDKCR PWTNCTFLGK
       190        200        210        220        230        240
RVEHHGTEKS DAVCSSSLPA RKPPNEPHVY LPGLIILLLF ASVALVAAII FGVCYRKKGK
       250        260        270        280        290        300
ALTANLWHWI NEACGRLSGD KESSGDSCVS THTANFGQQG ACEGVLLLTL EEKTFPEDMC
       310        320        330        340        350        360
YPDQGGVCQG TCVGGGPYAQ GEDARMLSLV SKTEIEEDSF RQMPTEDEYM DRPSQPTDQL
       370        380        390        400        410        420
LFLTEPGSKS TPPFSEPLEV GENDSLSQCF TGTQSTVGSE SCNCTEPLCR TDWTPMSSEN
       430        440        450        460        470        480
YLQKEVDSGH CPHWAASPSP NWADVCTGCR NPPGEDCEPL VGSPKRGPLP QCAYGMGLPP
       490        500        510        520        530        540
EEEASRTEAR DQPEDGADGR LPSSARAGAG SGSSPGGQSP ASGNVTGNSN STFISSGQVM
       550        560        570        580        590        600
NFKGDIIVVY VSQTSQEGAA AAAEPMGRPV QEETLARRDS FAGNGPRFPD PCGGPEGLRE
       610
PEKASRPVQE QGGAKA         10         20         30         40         50         60
MAPRARRRRP LFALLLLCAL LARLQVALQI APPCTSEKHY EHLGRCCNKC EPGKYMSSKC
        70         80         90        100        110        120
TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW
       130        140        150        160        170        180
SQDCECCRRN TECAPGLGAQ HPLQLNKDTV CKPCLAGYFS DAFSSTDKCR PWTNCTFLGK
       190        200        210        220        230        240
RVEHHGTEKS DAVCSSSLPA RKPPNEPHVY LPGLIILLLF ASVALVAAII FGVCYRKKGK
       250        260        270        280        290        300
ALTANLWHWI NEACGRLSGD KESSGDSCVS THTANFGQQG ACEGVLLLTL EEKTFPEDMC
       310        320        330        340        350        360
YPDQGGVCQG TCVGGGPYAQ GEDARMLSLV SKTEIEEDSF RQMPTEDEYM DRPSQPTDQL
       370        380        390        400        410        420
LFLTEPGSKS TPPFSEPLEV GENDSLSQCF TGTQSTVGSE SCNCTEPLCR TDWTPMSSEN
       430        440        450        460        470        480
YLQKEVDSGH CPHWAASPSP NWADVCTGCR NPPGEDCEPL VGSPKRGPLP QCAYGMGLPP
       490        500        510        520        530        540
EEEASRTEAR DQPEDGADGR LPSSARAGAG SGSSPGGQSP ASGNVTGNSN STFISSGQVM
       550        560        570        580        590        600
NFKGDIIVVY VSQTSQEGAA AAAEPMGRPV QEETLARRDS FAGNGPRFPD PCGGPEGLRE
       610
PEKASRPVQE QGGAKA         10         20         30         40         50         60
MAPRARRRRP LFALLLLCAL LARLQVALQI APPCTSEKHY EHLGRCCNKC EPGKYMSSKC
        70         80         90        100        110        120
TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW
       130        140        150        160        170        180
SQDCECCRRN TECAPGLGAQ HPLQLNKDTV CKPCLAGYFS DAFSSTDKCR PWTNCTFLGK
       190        200        210        220        230        240
RVEHHGTEKS DAVCSSSLPA RKPPNEPHVY LPGLIILLLF ASVALVAAII FGVCYRKKGK
       250        260        270        280        290        300
ALTANLWHWI NEACGRLSGD KESSGDSCVS THTANFGQQG ACEGVLLLTL EEKTFPEDMC
       310        320        330        340        350        360
YPDQGGVCQG TCVGGGPYAQ GEDARMLSLV SKTEIEEDSF RQMPTEDEYM DRPSQPTDQL
       370        380        390        400        410        420
LFLTEPGSKS TPPFSEPLEV GENDSLSQCF TGTQSTVGSE SCNCTEPLCR TDWTPMSSEN
       430        440        450        460        470        480
YLQKEVDSGH CPHWAASPSP NWADVCTGCR NPPGEDCEPL VGSPKRGPLP QCAYGMGLPP
       490        500        510        520        530        540
EEEASRTEAR DQPEDGADGR LPSSARAGAG SGSSPGGQSP ASGNVTGNSN STFISSGQVM
       550        560        570        580        590        600
NFKGDIIVVY VSQTSQEGAA AAAEPMGRPV QEETLARRDS FAGNGPRFPD PCGGPEGLRE
       610
PEKASRPVQE QGGAKA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y6Q6-1-unknown	MAPRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92680
Q9Y6Q6-1-unknown	MAPRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92681
Q9Y6Q6-1-unknown	MAPRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92682
Q9Y6Q6-1-unknown	MAPRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92683
Q9Y6Q6-1-unknown	MAPRAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92684
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114689
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114690
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114691
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114692
Q9Y6Q6-30-unknown	IAPPCT...	30	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114693

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGAKA	616	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GGAKA	616	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88298
...GGAKA	616	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88299
...GGAKA	616	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88302

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)