TopFIND 4.0

Q9Y6W6: Dual specificity protein phosphatase 10

General Information

Protein names
- Dual specificity protein phosphatase 10
- 3.1.3.16 {ECO:0000269|PubMed:16806267, ECO:0000269|PubMed:22375048}
- 3.1.3.48 {ECO:0000269|PubMed:16806267, ECO:0000269|PubMed:22375048}
- Mitogen-activated protein kinase phosphatase 5
- MAP kinase phosphatase 5
- MKP-5
Gene names DUSP10
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y6W6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPPSPLDDRV VVALSRPVRP QDLNLCLDSS YLGSANPGSN SHPPVIATTV VSLKAANLTY 
        70         80         90        100        110        120 
MPSSSGSARS LNCGCSSASC CTVATYDKDN QAQTQAIAAG TTTTAIGTST TCPANQMVNN 
       130        140        150        160        170        180 
NENTGSLSPS SGVGSPVSGT PKQLASIKII YPNDLAKKMT KCSKSHLPSQ GPVIIDCRPF 
       190        200        210        220        230        240 
MEYNKSHIQG AVHINCADKI SRRRLQQGKI TVLDLISCRE GKDSFKRIFS KEIIVYDENT 
       250        260        270        280        290        300 
NEPSRVMPSQ PLHIVLESLK REGKEPLVLK GGLSSFKQNH ENLCDNSLQL QECREVGGGA 
       310        320        330        340        350        360 
SAASSLLPQP IPTTPDIENA ELTPILPFLF LGNEQDAQDL DTMQRLNIGY VINVTTHLPL 
       370        380        390        400        410        420 
YHYEKGLFNY KRLPATDSNK QNLRQYFEEA FEFIEEAHQC GKGLLIHCQA GVSRSATIVI 
       430        440        450        460        470        480 
AYLMKHTRMT MTDAYKFVKG KRPIISPNLN FMGQLLEFEE DLNNGVTPRI LTPKLMGVET 
   
VV

Isoforms

- Isoform 2 of Dual specificity protein phosphatase 10

Sequence View

        10         20         30         40         50         60 
MPPSPLDDRV VVALSRPVRP QDLNLCLDSS YLGSANPGSN SHPPVIATTV VSLKAANLTY 
        70         80         90        100        110        120 
MPSSSGSARS LNCGCSSASC CTVATYDKDN QAQTQAIAAG TTTTAIGTST TCPANQMVNN 
       130        140        150        160        170        180 
NENTGSLSPS SGVGSPVSGT PKQLASIKII YPNDLAKKMT KCSKSHLPSQ GPVIIDCRPF 
       190        200        210        220        230        240 
MEYNKSHIQG AVHINCADKI SRRRLQQGKI TVLDLISCRE GKDSFKRIFS KEIIVYDENT 
       250        260        270        280        290        300 
NEPSRVMPSQ PLHIVLESLK REGKEPLVLK GGLSSFKQNH ENLCDNSLQL QECREVGGGA 
       310        320        330        340        350        360 
SAASSLLPQP IPTTPDIENA ELTPILPFLF LGNEQDAQDL DTMQRLNIGY VINVTTHLPL 
       370        380        390        400        410        420 
YHYEKGLFNY KRLPATDSNK QNLRQYFEEA FEFIEEAHQC GKGLLIHCQA GVSRSATIVI 
       430        440        450        460        470        480 
AYLMKHTRMT MTDAYKFVKG KRPIISPNLN FMGQLLEFEE DLNNGVTPRI LTPKLMGVET 
   
VV



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y6W6-1-unknown MPPSPL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y6W6-343-unknown MQRLNI... 343 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73342

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VETVV 482 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VETVV 482 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68960

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)