Q9Y6X2: E3 SUMO-protein ligase PIAS3

General Information

Protein names	- E3 SUMO-protein ligase PIAS3 - 2.3.2.- - E3 SUMO-protein transferase PIAS3 {ECO:0000305} - Protein inhibitor of activated STAT protein 3
Gene names	PIAS3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6X2

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAELGELKHM VMSFRVSELQ VLLGFAGRNK SGRKHELLAK ALHLLKSSCA PSVQMKIKEL
        70         80         90        100        110        120
YRRRFPRKTL GPSDLSLLSL PPGTSPVGSP GPLAPIPPTL LAPGTLLGPK REVDMHPPLP
       130        140        150        160        170        180
QPVHPDVTMK PLPFYEVYGE LIRPTTLAST SSQRFEEAHF TFALTPQQVQ QILTSREVLP
       190        200        210        220        230        240
GAKCDYTIQV QLRFCLCETS CPQEDYFPPN LFVKVNGKLC PLPGYLPPTK NGAEPKRPSR
       250        260        270        280        290        300
PINITPLARL SATVPNTIVV NWSSEFGRNY SLSVYLVRQL TAGTLLQKLR AKGIRNPDHS
       310        320        330        340        350        360
RALIKEKLTA DPDSEVATTS LRVSLMCPLG KMRLTVPCRA LTCAHLQSFD AALYLQMNEK
       370        380        390        400        410        420
KPTWTCPVCD KKAPYESLII DGLFMEILSS CSDCDEIQFM EDGSWCPMKP KKEASEVCPP
       430        440        450        460        470        480
PGYGLDGLQY SPVQGGDPSE NKKKVEVIDL TIESSSDEED LPPTKKHCSV TSAAIPALPG
       490        500        510        520        530        540
SKGVLTSGHQ PSSVLRSPAM GTLGGDFLSS LPLHEYPPAF PLGADIQGLD LFSFLQTESQ
       550        560        570        580        590        600
HYGPSVITSL DEQDALGHFF QYRGTPSHFL GPLAPTLGSS HCSATPAPPP GRVSSIVAPG
       610        620
GALREGHGGP LPSGPSLTGC RSDIISLD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y6X2-1-unknown	MAELGE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y6X2-10-unknown	MVMSFR...	10	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376766
Q9Y6X2-10-unknown	MVMSFR...	10	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000358305
Q9Y6X2-10-unknown	MVMSFR...	10	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464352
Q9Y6X2-10-unknown	MVMSFR...	10	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461923

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PVGSPG	90	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476245
...PVGSPG	90	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476209
...SEFGRN	268	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376766
...SEFGRN	268	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461923
...IISLD	628	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)