TopFIND 4.0

Q9Z1A5: NEDD8-activating enzyme E1 regulatory subunit

General Information

Protein names
- NEDD8-activating enzyme E1 regulatory subunit
- Amyloid beta precursor protein-binding protein 1, 59 kDa
- APP-BP1
- Amyloid protein-binding protein 1
Gene names Nae1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Z1A5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAQQGKILKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII 
        70         80         90        100        110        120 
DGNQVSGEDV GNNFFLQKCS IGKNRAQAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF 
       130        140        150        160        170        180 
CRFTIVVATQ LLESTLLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL 
       190        200        210        220        230        240 
EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK YLAQWYSETN GRIPKSYKEK 
       250        260        270        280        290        300 
EDFRELIRQG ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ 
       310        320        330        340        350        360 
TPSFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSNKYI KLQNVYREKA KKDAAAVGNH 
       370        380        390        400        410        420 
VAKLLQSCGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE EYGLHTVNKD EIISSMDNPD 
       430        440        450        460        470        480 
NEIVLYLMLR AVDRFHKQHG RYPGVSNYQV EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH 
       490        500        510        520        530    
EFCRYGAAEP HTVAAFLGGA AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Z1A5-2-unknown MAQQGK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Z1A5-2-Acetylation AQQGKI... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ATFQL 534 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)