TopFIND 4.0

Q9Z1C7: Rap guanine nucleotide exchange factor 4

General Information

Protein names
- Rap guanine nucleotide exchange factor 4
- Exchange factor directly activated by cAMP 2
- Exchange protein directly activated by cAMP 2
- EPAC 2
- cAMP-regulated guanine nucleotide exchange factor II
- cAMP-GEFII
Gene names Rapgef4
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Z1C7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
RVIRLVLQWA AMYGDLLQED DVAMAFLEEF YVSVSDDARM MVAFKEQLAE LEKTVKQISE 
        70         80         90        100        110        120 
DAKAPQKKHK VLLQQFNTGD ERAQKRQPIR GSDEVLFKVY CIDHTDTTIR VPVAASVKEV 
       130        140        150        160        170        180 
ISAVADKLGS GEGLIIVKMN SGGEKVVLKP NDVSVFTTLT INGRLFACPR EQFDSLTPLP 
       190        200        210        220        230        240 
EQEGPTTGTV GTFELMSSKD LAYQMTTYDW ELFNCVLELE LIYHTFGRHN FKKTTANLDL 
       250        260        270        280        290        300 
FLRRFNEIQF WVVTEICLCS QLSKRVQLLK KCIKIAAHCK EYKNLNSFFG IVMGLSNVAE 
       310        320        330        340        350        360 
SRLALTWEKL PSKFKKFYAE FESLMDPSRN HKAYRLTAAK LEPPLIPFMP LLIKDMTFTH 
       370        380        390        400        410        420 
EGNKTFIDNL VNFEKMRMIA NTARTVRYYR SQPFNPDAAQ ANKNHQDVRS YVRQLNVIDN 
       430    
QRTLSQMSHR LEPRRP

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Z1C7-1-unknown RVIRLV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EPRRP 436 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)