Q9Z1Q9: Valine--tRNA ligase

General Information

Protein names	- Valine--tRNA ligase - 6.1.1.9 - Protein G7a - Valyl-tRNA synthetase - ValRS
Gene names	Vars
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z1Q9

4 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSILYVSPHP DAFPSLRALI AARYGEAGDG PGWGGPHPRI CLQPPPSSRT PFPPPRLPAL
        70         80         90        100        110        120
EQGPGGLWVW GAPAVAQLLW PAGLGGPGGS RAAVLVQQWV SYADTELIPA ACGATLPALG
       130        140        150        160        170        180
LRGPGQDPQA ALGALGKALN PLEDWLRLHT YLAGDAPTLA DLAAVTALLL PFRYVLDPSA
       190        200        210        220        230        240
RRIWGNVTRW FNTCVRQPEF RAVLGEVALY SGARSVTQQP GSEVIAPQKT PAQLKKEAKK
       250        260        270        280        290        300
REKLEKFQQK QKTQQQPPHG EKKPKPEKKE KRDPGVITYD LPTPPGEKKD VSGAMPDSYS
       310        320        330        340        350        360
PQYVEAAWYP WWERQGFFKP EYGRPSVSAP NPRGVFMMCI PPPNVTGSLH LGHALTNAIQ
       370        380        390        400        410        420
DSLTRWHRMR GETTLWNPGC DHAGIATQVV VEKKLWKERG LNRHQLGREA FLEEVWKWKA
       430        440        450        460        470        480
EKGDRIYHQL KKLGSSLDWD RACFTMDPKL SATVTEAFVR LHEEGVIYRS TRLVNWSCTL
       490        500        510        520        530        540
NSAISDIEVD KKELTGRTLL PVPGYKEKVE FGVLVSFAYK VQGSDSDEEV VVATTRIETM
       550        560        570        580        590        600
LGDVAVAVHP KDPRYQHLKG KCVVHPFLSR SLPIVFDDFV DMEFGTGAVK ITPAHDQNDY
       610        620        630        640        650        660
EVGQRHRLEA ISIMDSKGAL INVPPPFLGL PRFEARKAVL AALKERGLFR GVKDNPMVVP
       670        680        690        700        710        720
LCNRSKDVVE PLLRPQWYVR CGEMAQAASA AVTRGDLRIL PEAHQRTWHS WMDNIRDWCI
       730        740        750        760        770        780
SRQLWWGHRI PAYFITVHDP AVPPGEDPDG RYWVSGRTEA EAREKAAREF GVSPDKISLQ
       790        800        810        820        830        840
QDEDVLDTWF SSGLFPFSIF GWPNQSEDLS VFYPGTLLET GHDILFFWVA RMVMLGLKLT
       850        860        870        880        890        900
GKLPFREVYL HAIVRDAHGR KMSKSLGNVI DPLDVIHGVS LQGLYDQLLN SNLDPSEVEK
       910        920        930        940        950        960
AKEGQKADFP AGIPECGTDA LRFGLCAYTS QGRDINLDVN RILGYRHFCN KLWNATKFAL
       970        980        990       1000       1010       1020
RGLGKGFVPS ATSKPEGHES LVDRWIRSRL TEAVRLSNEG FQAYDFPAIT TAQYSFWLYE
      1030       1040       1050       1060       1070       1080
LCDVYLECLK PVLNGVDQVA AECARQTLYT CLDVGLRLLS PFMPFVTEEL FQRLPRRTPK
      1090       1100       1110       1120       1130       1140
APASLCVTPY PEPSECSWKD PEAEAALELA LSITRAVRSL RADYNLTRTR PDCFLEVADE
      1150       1160       1170       1180       1190       1200
ATGALASAVS GYVQALASAG VVAVLALGAP APQGCAVAVA SDRCSIHLQL QGLVDPAREL
      1210       1220       1230       1240       1250       1260
GKLQAKRSEA QRQAQRLQER RAASSYSAKV PLEVQEADEA KLQQTEAELR KVDEAIALFQ

KML

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Z1Q9-2-unknown	MSILYV...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Z1Q9-2-unknown	MSILYV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z1Q9-2-Acetylation	SILYVS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z1Q9-2-Acetylation	SILYVS...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q9Z1Q9-2-Acetylation	SILYVS...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Z1Q9-219-unknown	QPGSEV...	219		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9Z1Q9-432-unmodified	KLGSSL...	432			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APQKTP	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134313
...KLEKFQ	247	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134245
...LSPFMP	1063	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134669
...FQKML	1263	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)