Q9Z2A0: 3-phosphoinositide-dependent protein kinase 1

General Information

Protein names	- 3-phosphoinositide-dependent protein kinase 1 - mPDK1 - 2.7.11.1
Gene names	Pdpk1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z2A0

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MARTTSQLYD AVPIQSSVVL CSCPSPSMVR SQTEPGSSPG IPSGVSRQGS TMDGTTAEAR
        70         80         90        100        110        120
PSTNPLQQHP AQLPPQPRKK RPEDFKFGKI LGEGSFSTVV LARELATSRE YAIKILEKRH
       130        140        150        160        170        180
IIKENKVPYV TRERDVMSRL DHPFFVKLYF TFQDDEKLYF GLSYAKNGEL LKYIRKIGSF
       190        200        210        220        230        240
DETCTRFYTA EIVSALEYLH GKGIIHRDLK PENILLNEDM HIQITDFGTA KVLSPESKQA
       250        260        270        280        290        300
RANSFVGTAQ YVSPELLTEK SACKSSDLWA LGCIIYQLVA GLPPFRAGNE YLIFQKIIKL
       310        320        330        340        350        360
EYHFPEKFFP KARDLVEKLL VLDATKRLGC EEMEGYGPLK AHPFFETITW ENLHQQTPPK
       370        380        390        400        410        420
LTAYLPAMSE DDEDCYGNYD NLLSQFGFMQ VSSSSSSHSL STVETSLPQR SGSNIEQYIH
       430        440        450        460        470        480
DLDTNSFELD LQFSEDEKRL LLEKQAGGNP WHQFVENNLI LKMGPVDKRK GLFARRRQLL
       490        500        510        520        530        540
LTEGPHLYYV DPVNKVLKGE IPWSQELRPE AKNFKTFFVH TPNRTYYLMD PSGNAHKWCR
       550
KIQEVWRQQY QSNPDAAVQ

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Z2A0-1-unknown	MARTTS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Z2A0-28-unknown	MVRSQT...	28	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000061942
Q9Z2A0-28-unknown	MVRSQT...	28	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121771
Q9Z2A0-28-unknown	MVRSQT...	28	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115618
Q9Z2A0-28-unknown	MVRSQT...	28	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120548

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKRPED	83	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120548
...RDVMSR	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115618
...TFQDDE	155	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121771
...DAAVQ	559	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)