TopFIND 4.0

Q9Z2D3: Gasdermin-E {ECO:0000250|UniProtKB:O60443}

General Information

Protein names
- Gasdermin-E {ECO:0000250|UniProtKB:O60443}
- Non-syndromic hearing impairment protein 5 homolog {ECO:0000305}
- Gasdermin-E, N-terminal {ECO:0000250|UniProtKB:O60443}
- GSDME-NT {ECO:0000250|UniProtKB:O60443}
- Gasdermin-E, C-terminal {ECO:0000250|UniProtKB:O60443}
- GSDME-CT {ECO:0000250|UniProtKB:O60443}
Gene names Dfna5
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Z2D3

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFAKATRNFL KEVDAGGDLI SVSHLNDSDK LQLLSLVTKK KRYWCWQRPK YQILSATLED 
        70         80         90        100        110        120 
VLTEGHCLSP VVVESDFVKY ESKCENHKSG AIGTVVGKVK LNVGGKGVVE SHSSFGTLRK 
       130        140        150        160        170        180 
QEVDVQQLIQ DAVKRTVNMD NLVLQQVLES RNEVLCVLTQ KIMTTQKCVI SEHVQSEETC 
       190        200        210        220        230        240 
GGMVGIQTKT IQVSATEDGT VTTDTNVVLE IPAATTIAYG IMELFVKQDG QFEFCLLQGK 
       250        260        270        280        290        300 
HGGFEHERKL DSVYLDPLAY REFAFLDMLD GGQGISSQDG PLRVVKQATL HLERSFHPFA 
       310        320        330        340        350        360 
VLPAQQQRAL FCVLQKILFD EELLRALEQV CDDVAGGLWS SQAVLAMEEL TDSQQQDLTA 
       370        380        390        400        410        420 
FLQLVGYRIQ GEHPGPQDEV SNQKLFATAY FLVSALAEMP DNATVFLGTC CKLHVISSLC 
       430        440        450        460        470        480 
CLLHALSDDS VCDFHNPTLA PLRDTERFGI VQRLFASADI ALERMQFSAK ATILKDSCIF 
       490        500        510    
PLILHITLSG LSTLSKEHEE ELCQSGHATG QD

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Z2D3-1-unknown MFAKAT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)