A2AGT5: Cytoskeleton-associated protein 5
Protein names | - Cytoskeleton-associated protein 5 |
---|---|
Gene names | Ckap5 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | A2AGT5 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGDDSEWLKL PVDQKCEHKL WKARLSGYEE ALKIFQKIKD EKSPEWSKYL GLIKKFVTDS
70 80 90 100 110 120
NAVVQLKGLE AALVYVENAH VAGKTTGEVV SGVVSKVFNQ PKAKAKELGI EICLMYVEIE
130 140 150 160 170 180
KGESVQEELL KGLDNKNPKI IVACIETLRK ALSEFGSKII SLKPIIKVLP KLFESRDKAV
190 200 210 220 230 240
RDEAKLFAIE IYRWNRDAVK HTLQNINSVQ LKELEEEWVK LPTGAPKPSR FLRSQQELEA
250 260 270 280 290 300
KLEQQQSAGG DAEGGGDDGD EVPQVDAYEL LDAVEILSKL PKDFYDKIEA KKWQERKEAL
310 320 330 340 350 360
EAVEVLVKNP KLEAGDYADL VKALKKVVGK DTNVMLVALA AKCLTGLAVG LRKKFGQYAG
370 380 390 400 410 420
HVVPTILEKF KEKKPQVVQA LQEAIDAIFL TTTLQNISED VLAVMDNKNP TIKQQTSLFI
430 440 450 460 470 480
ARSFRHCTSS TLPKSLLKPF CAALLKHIND SAPEVRDAAF EALGTALKVV GEKSVNPFLA
490 500 510 520 530 540
DVDKLKLDRI KECSEKVELV HGKKSGLATE KKESKPLPGR AAASGAAGDK DTKDVSGPKP
550 560 570 580 590 600
GPLKKTPTAK AGGPSKKGKT TAPGGSASAG TKNKKGLETK EIVEPELSIE VCEEKASAVL
610 620 630 640 650 660
PPTCIQLLDS SNWKERLACM EEFQKAVELM ERTEMPCQAL VKMLAKKPGW KETNFQVMQM
670 680 690 700 710 720
KLHIVALIAQ KGNFSKTSAQ IVLDGLVDKI GDVKCGNNAK EAMTAIAEAC MLPWTAEQVM
730 740 750 760 770 780
SMAFSQKNPK NQSETLNWLS NAIKEFGFSE LNVKAFISNV KTALAATNPA VRTSAITLLG
790 800 810 820 830 840
VMYLYVGPSL RMIFEDEKPA LLSQIDAEFQ KMQGQSPPAP TRGIAKHSTS ATDEGEDGEE
850 860 870 880 890 900
PGEGGNDVVD LLPRIEISDK ITSELVSKIG DKNWKIRKEG LDEVAGIINE AKFIQPNIGE
910 920 930 940 950 960
LPTALKGRLN DSNKILVQQT LNILQQLAVA MGANIRQHVK NLGIPVITVL GDSKNNVRAA
970 980 990 1000 1010 1020
ALATVNAWAE QTGMKEWLEG EDLSEELKKE NPFLRQELLG WLAEKLPTLR STPTDLILCV
1030 1040 1050 1060 1070 1080
PHLYSCLKDR NGDVRKKAQD ALPFFMMHLG YEKMAKATGK LKPTSKDQVL AMLEKAKANM
1090 1100 1110 1120 1130 1140
PSKPAAPAKA MSKPMGGSAP AKTQPIPAPV EDSVSSTIEA KPDLKKAKAP GVSSKAKSVQ
1150 1160 1170 1180 1190 1200
GKKVPSKTTL KEDDDKSGPI FIVVPNGKEQ RMRDEKGLKV LKWNFTTPRD EYIEQLKTQM
1210 1220 1230 1240 1250 1260
STCVAKWLQD EMFHSDFQHH NKALAVMVDH LESEKDGVIS CLDLILKWLT LRFFDTNTSV
1270 1280 1290 1300 1310 1320
LMKALEYLKL LFTLLSEEEY HLTENEASSF IPYLILKVGE PKDVIRKDVR AILNRMCLVY
1330 1340 1350 1360 1370 1380
PASKMFPFIM EGTKSKNSKQ RAECLEELGC LIESYGMNVC QPTPGKALKE IAIHIGDRDN
1390 1400 1410 1420 1430 1440
AVRNAALNTI VTVYNVHGDQ VFKLIGNLSE KDMSMLEERI KRSAKRPSAA PVKQAEEKPQ
1450 1460 1470 1480 1490 1500
RTQNINSNAN MLRKGPAEDM SSKLNQARSL SGHPEAAQMV RREFQLDLDE IENDNGTVRC
1510 1520 1530 1540 1550 1560
EMPELVQHKL DDIFEPVLIP EPKIRAVSPH FDDMHSNTAS TINFIISQVA SGDINTSIQA
1570 1580 1590 1600 1610 1620
LTQIDEVLRQ EDKAEAMSGH IDQFLIATFM QLRLIYSTHM ADEKLDKDEI IKLYSCIIGN
1630 1640 1650 1660 1670 1680
MISLFQIESL AREASTGVLK DLMHGLITLM LDSRIEDLEE GQQVIRSVNL LVVKVLEKSD
1690 1700 1710 1720 1730 1740
QTNILSALLV LLQDSLLATA SSPKFSELVM KCLWRMVRLL PDTINSINLD RILLDIHIFM
1750 1760 1770 1780 1790 1800
KVFPKEKLKQ CKSEFPIRTL KTLLHTLCKL KGPKILDHLT MIDNKNESEL EAHLCRMMKH
1810 1820 1830 1840 1850 1860
SMDQTGSKSD KETEKGASRI DEKSSKAKVN DFLAEIFKKI GSKENTKEGL AELYEYKKKY
1870 1880 1890 1900 1910 1920
SDTDIEPFLK NSSQFFQSYV ERGLRVIEME RESKGRIPTS TGISPQMEVT CVPTPTSTVS
1930 1940 1950 1960 1970 1980
SLGNTNGEEV GPSVYLERLK ILRQRCGLDN TKQDDRPPLT SLLSKPAIPP VASSTDMLHS
1990 2000 2010 2020 2030
KLSQLRESRE QHQHSDLDSN QTHSAGTMTS SSSTTNIDDL KKRLERIKSS RK
Isoforms
- Isoform 2 of Cytoskeleton-associated protein 5 - Isoform 3 of Cytoskeleton-associated protein 5Sequence View
10 20 30 40 50 60
MGDDSEWLKL PVDQKCEHKL WKARLSGYEE ALKIFQKIKD EKSPEWSKYL GLIKKFVTDS
70 80 90 100 110 120
NAVVQLKGLE AALVYVENAH VAGKTTGEVV SGVVSKVFNQ PKAKAKELGI EICLMYVEIE
130 140 150 160 170 180
KGESVQEELL KGLDNKNPKI IVACIETLRK ALSEFGSKII SLKPIIKVLP KLFESRDKAV
190 200 210 220 230 240
RDEAKLFAIE IYRWNRDAVK HTLQNINSVQ LKELEEEWVK LPTGAPKPSR FLRSQQELEA
250 260 270 280 290 300
KLEQQQSAGG DAEGGGDDGD EVPQVDAYEL LDAVEILSKL PKDFYDKIEA KKWQERKEAL
310 320 330 340 350 360
EAVEVLVKNP KLEAGDYADL VKALKKVVGK DTNVMLVALA AKCLTGLAVG LRKKFGQYAG
370 380 390 400 410 420
HVVPTILEKF KEKKPQVVQA LQEAIDAIFL TTTLQNISED VLAVMDNKNP TIKQQTSLFI
430 440 450 460 470 480
ARSFRHCTSS TLPKSLLKPF CAALLKHIND SAPEVRDAAF EALGTALKVV GEKSVNPFLA
490 500 510 520 530 540
DVDKLKLDRI KECSEKVELV HGKKSGLATE KKESKPLPGR AAASGAAGDK DTKDVSGPKP
550 560 570 580 590 600
GPLKKTPTAK AGGPSKKGKT TAPGGSASAG TKNKKGLETK EIVEPELSIE VCEEKASAVL
610 620 630 640 650 660
PPTCIQLLDS SNWKERLACM EEFQKAVELM ERTEMPCQAL VKMLAKKPGW KETNFQVMQM
670 680 690 700 710 720
KLHIVALIAQ KGNFSKTSAQ IVLDGLVDKI GDVKCGNNAK EAMTAIAEAC MLPWTAEQVM
730 740 750 760 770 780
SMAFSQKNPK NQSETLNWLS NAIKEFGFSE LNVKAFISNV KTALAATNPA VRTSAITLLG
790 800 810 820 830 840
VMYLYVGPSL RMIFEDEKPA LLSQIDAEFQ KMQGQSPPAP TRGIAKHSTS ATDEGEDGEE
850 860 870 880 890 900
PGEGGNDVVD LLPRIEISDK ITSELVSKIG DKNWKIRKEG LDEVAGIINE AKFIQPNIGE
910 920 930 940 950 960
LPTALKGRLN DSNKILVQQT LNILQQLAVA MGANIRQHVK NLGIPVITVL GDSKNNVRAA
970 980 990 1000 1010 1020
ALATVNAWAE QTGMKEWLEG EDLSEELKKE NPFLRQELLG WLAEKLPTLR STPTDLILCV
1030 1040 1050 1060 1070 1080
PHLYSCLKDR NGDVRKKAQD ALPFFMMHLG YEKMAKATGK LKPTSKDQVL AMLEKAKANM
1090 1100 1110 1120 1130 1140
PSKPAAPAKA MSKPMGGSAP AKTQPIPAPV EDSVSSTIEA KPDLKKAKAP GVSSKAKSVQ
1150 1160 1170 1180 1190 1200
GKKVPSKTTL KEDDDKSGPI FIVVPNGKEQ RMRDEKGLKV LKWNFTTPRD EYIEQLKTQM
1210 1220 1230 1240 1250 1260
STCVAKWLQD EMFHSDFQHH NKALAVMVDH LESEKDGVIS CLDLILKWLT LRFFDTNTSV
1270 1280 1290 1300 1310 1320
LMKALEYLKL LFTLLSEEEY HLTENEASSF IPYLILKVGE PKDVIRKDVR AILNRMCLVY
1330 1340 1350 1360 1370 1380
PASKMFPFIM EGTKSKNSKQ RAECLEELGC LIESYGMNVC QPTPGKALKE IAIHIGDRDN
1390 1400 1410 1420 1430 1440
AVRNAALNTI VTVYNVHGDQ VFKLIGNLSE KDMSMLEERI KRSAKRPSAA PVKQAEEKPQ
1450 1460 1470 1480 1490 1500
RTQNINSNAN MLRKGPAEDM SSKLNQARSL SGHPEAAQMV RREFQLDLDE IENDNGTVRC
1510 1520 1530 1540 1550 1560
EMPELVQHKL DDIFEPVLIP EPKIRAVSPH FDDMHSNTAS TINFIISQVA SGDINTSIQA
1570 1580 1590 1600 1610 1620
LTQIDEVLRQ EDKAEAMSGH IDQFLIATFM QLRLIYSTHM ADEKLDKDEI IKLYSCIIGN
1630 1640 1650 1660 1670 1680
MISLFQIESL AREASTGVLK DLMHGLITLM LDSRIEDLEE GQQVIRSVNL LVVKVLEKSD
1690 1700 1710 1720 1730 1740
QTNILSALLV LLQDSLLATA SSPKFSELVM KCLWRMVRLL PDTINSINLD RILLDIHIFM
1750 1760 1770 1780 1790 1800
KVFPKEKLKQ CKSEFPIRTL KTLLHTLCKL KGPKILDHLT MIDNKNESEL EAHLCRMMKH
1810 1820 1830 1840 1850 1860
SMDQTGSKSD KETEKGASRI DEKSSKAKVN DFLAEIFKKI GSKENTKEGL AELYEYKKKY
1870 1880 1890 1900 1910 1920
SDTDIEPFLK NSSQFFQSYV ERGLRVIEME RESKGRIPTS TGISPQMEVT CVPTPTSTVS
1930 1940 1950 1960 1970 1980
SLGNTNGEEV GPSVYLERLK ILRQRCGLDN TKQDDRPPLT SLLSKPAIPP VASSTDMLHS
1990 2000 2010 2020 2030
KLSQLRESRE QHQHSDLDSN QTHSAGTMTS SSSTTNIDDL KKRLERIKSS RK
10 20 30 40 50 60
MGDDSEWLKL PVDQKCEHKL WKARLSGYEE ALKIFQKIKD EKSPEWSKYL GLIKKFVTDS
70 80 90 100 110 120
NAVVQLKGLE AALVYVENAH VAGKTTGEVV SGVVSKVFNQ PKAKAKELGI EICLMYVEIE
130 140 150 160 170 180
KGESVQEELL KGLDNKNPKI IVACIETLRK ALSEFGSKII SLKPIIKVLP KLFESRDKAV
190 200 210 220 230 240
RDEAKLFAIE IYRWNRDAVK HTLQNINSVQ LKELEEEWVK LPTGAPKPSR FLRSQQELEA
250 260 270 280 290 300
KLEQQQSAGG DAEGGGDDGD EVPQVDAYEL LDAVEILSKL PKDFYDKIEA KKWQERKEAL
310 320 330 340 350 360
EAVEVLVKNP KLEAGDYADL VKALKKVVGK DTNVMLVALA AKCLTGLAVG LRKKFGQYAG
370 380 390 400 410 420
HVVPTILEKF KEKKPQVVQA LQEAIDAIFL TTTLQNISED VLAVMDNKNP TIKQQTSLFI
430 440 450 460 470 480
ARSFRHCTSS TLPKSLLKPF CAALLKHIND SAPEVRDAAF EALGTALKVV GEKSVNPFLA
490 500 510 520 530 540
DVDKLKLDRI KECSEKVELV HGKKSGLATE KKESKPLPGR AAASGAAGDK DTKDVSGPKP
550 560 570 580 590 600
GPLKKTPTAK AGGPSKKGKT TAPGGSASAG TKNKKGLETK EIVEPELSIE VCEEKASAVL
610 620 630 640 650 660
PPTCIQLLDS SNWKERLACM EEFQKAVELM ERTEMPCQAL VKMLAKKPGW KETNFQVMQM
670 680 690 700 710 720
KLHIVALIAQ KGNFSKTSAQ IVLDGLVDKI GDVKCGNNAK EAMTAIAEAC MLPWTAEQVM
730 740 750 760 770 780
SMAFSQKNPK NQSETLNWLS NAIKEFGFSE LNVKAFISNV KTALAATNPA VRTSAITLLG
790 800 810 820 830 840
VMYLYVGPSL RMIFEDEKPA LLSQIDAEFQ KMQGQSPPAP TRGIAKHSTS ATDEGEDGEE
850 860 870 880 890 900
PGEGGNDVVD LLPRIEISDK ITSELVSKIG DKNWKIRKEG LDEVAGIINE AKFIQPNIGE
910 920 930 940 950 960
LPTALKGRLN DSNKILVQQT LNILQQLAVA MGANIRQHVK NLGIPVITVL GDSKNNVRAA
970 980 990 1000 1010 1020
ALATVNAWAE QTGMKEWLEG EDLSEELKKE NPFLRQELLG WLAEKLPTLR STPTDLILCV
1030 1040 1050 1060 1070 1080
PHLYSCLKDR NGDVRKKAQD ALPFFMMHLG YEKMAKATGK LKPTSKDQVL AMLEKAKANM
1090 1100 1110 1120 1130 1140
PSKPAAPAKA MSKPMGGSAP AKTQPIPAPV EDSVSSTIEA KPDLKKAKAP GVSSKAKSVQ
1150 1160 1170 1180 1190 1200
GKKVPSKTTL KEDDDKSGPI FIVVPNGKEQ RMRDEKGLKV LKWNFTTPRD EYIEQLKTQM
1210 1220 1230 1240 1250 1260
STCVAKWLQD EMFHSDFQHH NKALAVMVDH LESEKDGVIS CLDLILKWLT LRFFDTNTSV
1270 1280 1290 1300 1310 1320
LMKALEYLKL LFTLLSEEEY HLTENEASSF IPYLILKVGE PKDVIRKDVR AILNRMCLVY
1330 1340 1350 1360 1370 1380
PASKMFPFIM EGTKSKNSKQ RAECLEELGC LIESYGMNVC QPTPGKALKE IAIHIGDRDN
1390 1400 1410 1420 1430 1440
AVRNAALNTI VTVYNVHGDQ VFKLIGNLSE KDMSMLEERI KRSAKRPSAA PVKQAEEKPQ
1450 1460 1470 1480 1490 1500
RTQNINSNAN MLRKGPAEDM SSKLNQARSL SGHPEAAQMV RREFQLDLDE IENDNGTVRC
1510 1520 1530 1540 1550 1560
EMPELVQHKL DDIFEPVLIP EPKIRAVSPH FDDMHSNTAS TINFIISQVA SGDINTSIQA
1570 1580 1590 1600 1610 1620
LTQIDEVLRQ EDKAEAMSGH IDQFLIATFM QLRLIYSTHM ADEKLDKDEI IKLYSCIIGN
1630 1640 1650 1660 1670 1680
MISLFQIESL AREASTGVLK DLMHGLITLM LDSRIEDLEE GQQVIRSVNL LVVKVLEKSD
1690 1700 1710 1720 1730 1740
QTNILSALLV LLQDSLLATA SSPKFSELVM KCLWRMVRLL PDTINSINLD RILLDIHIFM
1750 1760 1770 1780 1790 1800
KVFPKEKLKQ CKSEFPIRTL KTLLHTLCKL KGPKILDHLT MIDNKNESEL EAHLCRMMKH
1810 1820 1830 1840 1850 1860
SMDQTGSKSD KETEKGASRI DEKSSKAKVN DFLAEIFKKI GSKENTKEGL AELYEYKKKY
1870 1880 1890 1900 1910 1920
SDTDIEPFLK NSSQFFQSYV ERGLRVIEME RESKGRIPTS TGISPQMEVT CVPTPTSTVS
1930 1940 1950 1960 1970 1980
SLGNTNGEEV GPSVYLERLK ILRQRCGLDN TKQDDRPPLT SLLSKPAIPP VASSTDMLHS
1990 2000 2010 2020 2030
KLSQLRESRE QHQHSDLDSN QTHSAGTMTS SSSTTNIDDL KKRLERIKSS RK
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
A2AGT5-1-unknown | MGDDSE... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
A2AGT5-1-unknown | MGDDSE... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt70766 | |||
A2AGT5-1-unknown | MGDDSE... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt70767 | |||
A2AGT5-1488-unknown | LDEIEN... | 1488 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32274 | |||
A2AGT5-1488-unknown | LDEIEN... | 1488 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158188 | |||
A2AGT5-1488-unknown | LDEIEN... | 1488 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158189 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EFQLDL | 1487 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32274 | |||
...EFQLDL | 1487 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141684 | |||
...EFQLDL | 1487 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141685 | |||
...KSSRK | 2032 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KSSRK | 2032 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt66384 | |||
...KSSRK | 2032 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt66385 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_MOUSE | 1487 | QLDL.|.LDEI | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|