TopFIND 4.0

P04187: Granzyme B(G,H)

General Information

Protein names
- Granzyme B(G,H)
- 3.4.21.79
- CTLA-1
- Cytotoxic cell protease 1
- CCP1
- Fragmentin-2
Gene names Gzmb
Organism Mus musculus
Protease Family S01.136
Protease ID S01.136
Chromosome location
UniProt ID P04187

1

N-termini

2

C-termini

1

Cleavages

331

Substrates

Sequence

        10         20         30         40         50         60 
MKILLLLLTL SLASRTKAGE IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL 
        70         80         90        100        110        120 
TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR 
       130        140        150        160        170        180 
TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR 
       190        200        210        220        230        240 
YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI 
   
KKTMKSS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 331 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P04187-21-unknown IIGGHE... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P04187-21-unknown IIGGHE... 21 inferred from cleavage unknown TopFIND Inferred from cleavage TC28622

C-termini

Cleavages

Substrates