Q3UZ39: Leucine-rich repeat flightless-interacting protein 1
Protein names | - Leucine-rich repeat flightless-interacting protein 1 - LRR FLII-interacting protein 1 - FLI-LRR-associated protein 1 - Flap-1 - H186 FLAP |
---|---|
Gene names | Lrrfip1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q3UZ39 |
12
N-termini
6
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTSPEGAQNK EIDCLSPEAQ RLAEARLAAK RAARAEAREI RMKELERQQK EVEERPDKDF
70 80 90 100 110 120
AEKGSRNMPS LSAATLASLG GTSSRRGSGD TSISMDTEAS IREIKDSLAE VEEKYKKAMV
130 140 150 160 170 180
SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESQRQYEEK NKEFEREKHA HSILQFQFAE
190 200 210 220 230 240
VKEALRQREE MLEKHGIILN SEIATNGETS DTVNDVGYQA PTKITKEELN ALKSAGEGTL
250 260 270 280 290 300
GKAKEVEVKK EIVEKVGQRE TLQNSEQEQP KPNTGKDCVD RGVSHPGEKA ENQRPAEDSA
310 320 330 340 350 360
LSPGPLAGAK CEQQVQSQDQ ENTSDLKNSE QIESHKVTNK SDSRASNSPE QSSCLEGLDS
370 380 390 400 410 420
EVPGPTEDLK TDLGKGSFEP CPDYILGQTA EIDKVTCTDS RGTGGNQRED EVQAGDTTVE
430 440 450 460 470 480
DQVGTVASGP AKQSKGTENH GESCLKDGLG QSSERELTQE VAEPEEAIVQ IPQAGGENTI
490 500 510 520 530 540
TKADDAEGRD EKPIQAEAQA SPGAPINQSG HQDTTGPGST DAQRTPPHAK ERKKQGKSEQ
550 560 570 580 590 600
QAEALDSPQK KTKNKKKKNK KKKAATPAET CRDANEELNC QDPDVGDMEE EERLQVTDKK
610 620 630 640 650 660
QASGSPEQKI RAGSREPVED PQSGSSGKQN KVEEDGPTEG PTDILDQNSP QCEDREISPV
670 680 690 700 710 720
GEKGPQCDTS QIGSEEGHVT SQHGGQAVEN HNLDNSDLSG QLEGFNSESG GQAREEVGNS
KSKEDCTMS
Isoforms
- Isoform 2 of Leucine-rich repeat flightless-interacting protein 1 - Isoform 3 of Leucine-rich repeat flightless-interacting protein 1 - Isoform 3 of Leucine-rich repeat flightless-interacting protein 1Sequence View
10 20 30 40 50 60
MTSPEGAQNK EIDCLSPEAQ RLAEARLAAK RAARAEAREI RMKELERQQK EVEERPDKDF
70 80 90 100 110 120
AEKGSRNMPS LSAATLASLG GTSSRRGSGD TSISMDTEAS IREIKDSLAE VEEKYKKAMV
130 140 150 160 170 180
SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESQRQYEEK NKEFEREKHA HSILQFQFAE
190 200 210 220 230 240
VKEALRQREE MLEKHGIILN SEIATNGETS DTVNDVGYQA PTKITKEELN ALKSAGEGTL
250 260 270 280 290 300
GKAKEVEVKK EIVEKVGQRE TLQNSEQEQP KPNTGKDCVD RGVSHPGEKA ENQRPAEDSA
310 320 330 340 350 360
LSPGPLAGAK CEQQVQSQDQ ENTSDLKNSE QIESHKVTNK SDSRASNSPE QSSCLEGLDS
370 380 390 400 410 420
EVPGPTEDLK TDLGKGSFEP CPDYILGQTA EIDKVTCTDS RGTGGNQRED EVQAGDTTVE
430 440 450 460 470 480
DQVGTVASGP AKQSKGTENH GESCLKDGLG QSSERELTQE VAEPEEAIVQ IPQAGGENTI
490 500 510 520 530 540
TKADDAEGRD EKPIQAEAQA SPGAPINQSG HQDTTGPGST DAQRTPPHAK ERKKQGKSEQ
550 560 570 580 590 600
QAEALDSPQK KTKNKKKKNK KKKAATPAET CRDANEELNC QDPDVGDMEE EERLQVTDKK
610 620 630 640 650 660
QASGSPEQKI RAGSREPVED PQSGSSGKQN KVEEDGPTEG PTDILDQNSP QCEDREISPV
670 680 690 700 710 720
GEKGPQCDTS QIGSEEGHVT SQHGGQAVEN HNLDNSDLSG QLEGFNSESG GQAREEVGNS
KSKEDCTMS
10 20 30 40 50 60
MTSPEGAQNK EIDCLSPEAQ RLAEARLAAK RAARAEAREI RMKELERQQK EVEERPDKDF
70 80 90 100 110 120
AEKGSRNMPS LSAATLASLG GTSSRRGSGD TSISMDTEAS IREIKDSLAE VEEKYKKAMV
130 140 150 160 170 180
SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESQRQYEEK NKEFEREKHA HSILQFQFAE
190 200 210 220 230 240
VKEALRQREE MLEKHGIILN SEIATNGETS DTVNDVGYQA PTKITKEELN ALKSAGEGTL
250 260 270 280 290 300
GKAKEVEVKK EIVEKVGQRE TLQNSEQEQP KPNTGKDCVD RGVSHPGEKA ENQRPAEDSA
310 320 330 340 350 360
LSPGPLAGAK CEQQVQSQDQ ENTSDLKNSE QIESHKVTNK SDSRASNSPE QSSCLEGLDS
370 380 390 400 410 420
EVPGPTEDLK TDLGKGSFEP CPDYILGQTA EIDKVTCTDS RGTGGNQRED EVQAGDTTVE
430 440 450 460 470 480
DQVGTVASGP AKQSKGTENH GESCLKDGLG QSSERELTQE VAEPEEAIVQ IPQAGGENTI
490 500 510 520 530 540
TKADDAEGRD EKPIQAEAQA SPGAPINQSG HQDTTGPGST DAQRTPPHAK ERKKQGKSEQ
550 560 570 580 590 600
QAEALDSPQK KTKNKKKKNK KKKAATPAET CRDANEELNC QDPDVGDMEE EERLQVTDKK
610 620 630 640 650 660
QASGSPEQKI RAGSREPVED PQSGSSGKQN KVEEDGPTEG PTDILDQNSP QCEDREISPV
670 680 690 700 710 720
GEKGPQCDTS QIGSEEGHVT SQHGGQAVEN HNLDNSDLSG QLEGFNSESG GQAREEVGNS
KSKEDCTMS
10 20 30 40 50 60
MTSPEGAQNK EIDCLSPEAQ RLAEARLAAK RAARAEAREI RMKELERQQK EVEERPDKDF
70 80 90 100 110 120
AEKGSRNMPS LSAATLASLG GTSSRRGSGD TSISMDTEAS IREIKDSLAE VEEKYKKAMV
130 140 150 160 170 180
SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESQRQYEEK NKEFEREKHA HSILQFQFAE
190 200 210 220 230 240
VKEALRQREE MLEKHGIILN SEIATNGETS DTVNDVGYQA PTKITKEELN ALKSAGEGTL
250 260 270 280 290 300
GKAKEVEVKK EIVEKVGQRE TLQNSEQEQP KPNTGKDCVD RGVSHPGEKA ENQRPAEDSA
310 320 330 340 350 360
LSPGPLAGAK CEQQVQSQDQ ENTSDLKNSE QIESHKVTNK SDSRASNSPE QSSCLEGLDS
370 380 390 400 410 420
EVPGPTEDLK TDLGKGSFEP CPDYILGQTA EIDKVTCTDS RGTGGNQRED EVQAGDTTVE
430 440 450 460 470 480
DQVGTVASGP AKQSKGTENH GESCLKDGLG QSSERELTQE VAEPEEAIVQ IPQAGGENTI
490 500 510 520 530 540
TKADDAEGRD EKPIQAEAQA SPGAPINQSG HQDTTGPGST DAQRTPPHAK ERKKQGKSEQ
550 560 570 580 590 600
QAEALDSPQK KTKNKKKKNK KKKAATPAET CRDANEELNC QDPDVGDMEE EERLQVTDKK
610 620 630 640 650 660
QASGSPEQKI RAGSREPVED PQSGSSGKQN KVEEDGPTEG PTDILDQNSP QCEDREISPV
670 680 690 700 710 720
GEKGPQCDTS QIGSEEGHVT SQHGGQAVEN HNLDNSDLSG QLEGFNSESG GQAREEVGNS
KSKEDCTMS
Protein Neighborhood
Domains & Features
12 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q3UZ39-1-unknown | MTSPEG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79979 | |||
Q3UZ39-2-unknown | MTSPEG... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q3UZ39-2-unknown | MTSPEG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q3UZ39-2-Acetylation | TSPEGA... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q3UZ39-2-Acetylation | TSPEGA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111642 | ||
Q3UZ39-2-Acetylation | TSPEGA... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q3UZ39-77-unknown | ASLGGT... | 77 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30438 | |||
Q3UZ39-77-unknown | ASLGGT... | 77 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147564 | |||
Q3UZ39-106-unknown | DSLAEV... | 106 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q3UZ39-106-unknown | DSLAEV... | 106 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt197071 | |||
Q3UZ39-144-unknown | LELEEQ... | 144 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q3UZ39-144-unknown | LELEEQ... | 144 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt197570 | |||
Q3UZ39-147-unknown | EEQLAE... | 147 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29128 | |||
Q3UZ39-147-unknown | EEQLAE... | 147 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150314 | |||
Q3UZ39-172-unknown | SILQFQ... | 172 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q3UZ39-172-unknown | SILQFQ... | 172 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt197826 | |||
Q3UZ39-179-unknown | AEVKEA... | 179 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30440 | |||
Q3UZ39-186-unknown | RQREEM... | 186 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
Q3UZ39-387-unknown | GQTAEI... | 387 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30442 | |||
Q3UZ39-387-unknown | GQTAEI... | 387 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144702 | |||
Q3UZ39-585-unknown | VGDMEE... | 585 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32445 | |||
Q3UZ39-585-unknown | VGDMEE... | 585 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150895 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SAATLA | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30438 | |||
...SAATLA | 76 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130916 | |||
...MLLELE | 146 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29128 | |||
...MLLELE | 146 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133709 | |||
...LQFQFA | 178 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30440 | |||
...LQFQFA | 178 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134372 | |||
...PDYILG | 386 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30442 | |||
...PDYILG | 386 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127970 | |||
...CQDPDV | 584 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32445 | |||
...CQDPDV | 584 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134297 | |||
...DCTMS | 729 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...DCTMS | 729 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt75598 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 76 | ATLA.|.ASLG | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> LRRF1_MOUSE @76 | ||
CATD_MOUSE | 146 | LELE.|.EEQL | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> LRRF1_MOUSE @146 | ||
CATE_MOUSE | 178 | FQFA.|.AEVK | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> LRRF1_MOUSE @178 | ||
CATE_MOUSE | 386 | YILG.|.GQTA | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> LRRF1_MOUSE @386 | ||
GRAB_MOUSE | 584 | DPDV.|.VGDM | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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