P0C0S6: Histone H2A.Z

General Information

Protein names	- Histone H2A.Z - H2A/z
Gene names	H2afz
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P0C0S6

7 N-termini

6 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGGKAGKDS GKAKTKAVSR SQRAGLQFPV GRIHRHLKSR TTSHGRVGAT AAVYSAAILE
        70         80         90        100        110        120
YLTAEVLELA GNASKDLKVK RITPRHLQLA IRGDEELDSL IKATIAGGGV IPHIHKSLIG

KKGQQKTV

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P0C0S6-2-unknown	MAGGKA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P0C0S6-2-unknown	MAGGKA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P0C0S6-2-Acetylation	AGGKAG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P0C0S6-2-Acetylation	AGGKAG...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P0C0S6-10-unknown	SGKAKT...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32305
P0C0S6-63-unknown	TAEVLE...	63		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29668
P0C0S6-66-unknown	VLELAG...	66		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28735
P0C0S6-66-unknown	VLELAG...	66		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29669
P0C0S6-68-unknown	ELAGNA...	68		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28736
P0C0S6-68-unknown	ELAGNA...	68		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29670
P0C0S6-70-unknown	AGNASK...	70		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28737
P0C0S6-70-unknown	AGNASK...	70		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29671

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KAGKDS	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32305
...ILEYLT	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29668
...YLTAEV	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28735
...YLTAEV	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29669
...TAEVLE	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28736
...TAEVLE	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29670
...EVLELA	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28737
...EVLELA	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29671
...QQKTV	128	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	9	GKDS.\|.SGKA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATE_MOUSE	62	EYLT.\|.TAEV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> H2AZ_MOUSE @62
CATD_MOUSE	65	TAEV.\|.VLEL	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	65	TAEV.\|.VLEL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> H2AZ_MOUSE @65
CATD_MOUSE	67	EVLE.\|.ELAG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> H2AZ_MOUSE @67
CATE_MOUSE	67	EVLE.\|.ELAG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> H2AZ_MOUSE @67
CATD_MOUSE	69	LELA.\|.AGNA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> H2AZ_MOUSE @69
CATE_MOUSE	69	LELA.\|.AGNA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> H2AZ_MOUSE @69

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)