TopFIND 4.0

P46062: Signal-induced proliferation-associated protein 1

General Information

Protein names
- Signal-induced proliferation-associated protein 1
- Sipa-1
- GTPase-activating protein Spa-1

Gene names Sipa1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P46062

4

N-termini

4

C-termini

3

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWAGGVGSPR RGMAPAPTDD LFARKLRQPA RPPLTPNTFE PRPARGPLLR SGSDAGEVRP 
        70         80         90        100        110        120 
PTPASPRARA HSHEDASRPA ATPTRLFTDP LALLGLPAEE PEPTFPPVLE PRWFAHYDVQ 
       130        140        150        160        170        180 
SLLFDWAPRP RGTGSHTEAN SGTLAEGQTT TSDLLLGAPG FVSELGGEGE LGLGGPISPP 
       190        200        210        220        230        240 
VPPALPNAAV SVLEEPQTRT TTYSLEHADL GAGYYRKYFY GKEHQNFFGL DEALGPVAVS 
       250        260        270        280        290        300 
LRREEKEGSG GGTLHSYRVI VRTTQLRTLR GTISEDALPP GPPSVSPRKL LEHVAPRLSP 
       310        320        330        340        350        360 
TCLRLGSASP KVPRQLLTLD EQVLSFQRKG GILYCRAGQG SEEEMYNNQE AGAAFMQFLT 
       370        380        390        400        410        420 
LLGDVVRLKG FESYRAQLDT KTDSTGTHSL YTTYQDHEIM FHVSTMLPYT PNNQQQLLRK 
       430        440        450        460        470        480 
RHIGNDIVTI VFQEPGSKPF CPTTIRSHFQ HVFLVVRAHA PCTPHTSYRV AVSRTQDTPA 
       490        500        510        520        530        540 
FGPALPEGGG PFAANADFRA FLLAKALNGE QAAGHARQFH AMATRTRQQY LQDLATNEVT 
       550        560        570        580        590        600 
TTSLDSASRF GLPSLGGRRR ATPRSPGADV QAAGALMWGV RAAPGARVAA GAETSGPDDA 
       610        620        630        640        650        660 
EVPCLLGISA ETLVLVAPRD GRVVFNCACR DVLAWTFSEH QLDLYHGRGE AITLRLDGAP 
       670        680        690        700        710        720 
GQAVGEVVAR LQLVSRGCET RELALPRDGQ GRLGFEVDAE GFITHVERFT FAETTGLRPG 
       730        740        750        760        770        780 
ARLLRVCGQT LPKLGPETAA QMLRSAPKVC VTVLPPDESG RPRRSFSELY MLSLKEPSRR 
       790        800        810        820        830        840 
GGPEPVQDET GKLVILPPTK QLLHFCLKDS SSPPGPGDLT EERTEFLRTH NSLSSGSSLS 
       850        860        870        880        890        900 
DEAPVLPNTT PDLLLVTTAN PSAPGTDRET PPSQDQSGSP SSHEDTSDSG PELRASILPR 
       910        920        930        940        950        960 
TLSLRNSISK IMSEAGSETL EDEWQSISEI ASTCNTILES LSREGQPISE SGDPKEALKC 
       970        980        990       1000       1010       1020 
DSEPEPGSLS EKVSHLESML WKLQEDLQRE KADRAALEEE VRSLRHNNQR LLAESESAAT 
      1030    
RLLLASKHLG APTTDLA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)