P46062: Signal-induced proliferation-associated protein 1
Protein names | - Signal-induced proliferation-associated protein 1 - Sipa-1 - GTPase-activating protein Spa-1 |
---|---|
Gene names | Sipa1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P46062 |
4
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MWAGGVGSPR RGMAPAPTDD LFARKLRQPA RPPLTPNTFE PRPARGPLLR SGSDAGEVRP
70 80 90 100 110 120
PTPASPRARA HSHEDASRPA ATPTRLFTDP LALLGLPAEE PEPTFPPVLE PRWFAHYDVQ
130 140 150 160 170 180
SLLFDWAPRP RGTGSHTEAN SGTLAEGQTT TSDLLLGAPG FVSELGGEGE LGLGGPISPP
190 200 210 220 230 240
VPPALPNAAV SVLEEPQTRT TTYSLEHADL GAGYYRKYFY GKEHQNFFGL DEALGPVAVS
250 260 270 280 290 300
LRREEKEGSG GGTLHSYRVI VRTTQLRTLR GTISEDALPP GPPSVSPRKL LEHVAPRLSP
310 320 330 340 350 360
TCLRLGSASP KVPRQLLTLD EQVLSFQRKG GILYCRAGQG SEEEMYNNQE AGAAFMQFLT
370 380 390 400 410 420
LLGDVVRLKG FESYRAQLDT KTDSTGTHSL YTTYQDHEIM FHVSTMLPYT PNNQQQLLRK
430 440 450 460 470 480
RHIGNDIVTI VFQEPGSKPF CPTTIRSHFQ HVFLVVRAHA PCTPHTSYRV AVSRTQDTPA
490 500 510 520 530 540
FGPALPEGGG PFAANADFRA FLLAKALNGE QAAGHARQFH AMATRTRQQY LQDLATNEVT
550 560 570 580 590 600
TTSLDSASRF GLPSLGGRRR ATPRSPGADV QAAGALMWGV RAAPGARVAA GAETSGPDDA
610 620 630 640 650 660
EVPCLLGISA ETLVLVAPRD GRVVFNCACR DVLAWTFSEH QLDLYHGRGE AITLRLDGAP
670 680 690 700 710 720
GQAVGEVVAR LQLVSRGCET RELALPRDGQ GRLGFEVDAE GFITHVERFT FAETTGLRPG
730 740 750 760 770 780
ARLLRVCGQT LPKLGPETAA QMLRSAPKVC VTVLPPDESG RPRRSFSELY MLSLKEPSRR
790 800 810 820 830 840
GGPEPVQDET GKLVILPPTK QLLHFCLKDS SSPPGPGDLT EERTEFLRTH NSLSSGSSLS
850 860 870 880 890 900
DEAPVLPNTT PDLLLVTTAN PSAPGTDRET PPSQDQSGSP SSHEDTSDSG PELRASILPR
910 920 930 940 950 960
TLSLRNSISK IMSEAGSETL EDEWQSISEI ASTCNTILES LSREGQPISE SGDPKEALKC
970 980 990 1000 1010 1020
DSEPEPGSLS EKVSHLESML WKLQEDLQRE KADRAALEEE VRSLRHNNQR LLAESESAAT
1030
RLLLASKHLG APTTDLA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P46062-1-unknown | MWAGGV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P46062-539-unknown | VTTTSL... | 539 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29960 | |||
P46062-853-unknown | LLLVTT... | 853 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32343 | |||
P46062-1012-unknown | LAESES... | 1012 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29961 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LATNEV | 538 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29960 | |||
...NTTPDL | 852 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32343 | |||
...NNQRLL | 1011 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29961 | |||
...TTDLA | 1037 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 538 | TNEV.|.VTTT | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SIPA1_MOUSE @538 | ||
GRAB_MOUSE | 852 | TPDL.|.LLLV | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
CATE_MOUSE | 1011 | QRLL.|.LAES | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> SIPA1_MOUSE @1011 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|