TopFIND 4.0

P54276: DNA mismatch repair protein Msh6 {ECO:0000303|PubMed:9390556}

General Information

Protein names
- DNA mismatch repair protein Msh6 {ECO:0000303|PubMed:9390556}
- G/T mismatch-binding protein {ECO:0000303|PubMed:8812455}
- GTBP {ECO:0000250|UniProtKB:P52701}
- GTMBP {ECO:0000303|PubMed:8812455}
- MutS protein homolog 6 {ECO:0000250|UniProtKB:P52701}
- MutS-alpha 160 kDa subunit
- p160 {ECO:0000250|UniProtKB:P52701}
Gene names Msh6
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P54276

3

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRQSTLYSF FPKSPALGDT KKAAAEASRQ GAAASGASAS RGGDAAWSEA EPGSRSAAVS 
        70         80         90        100        110        120 
ASSPEAKDLN GGLRRASSSA QAVPPSSCDF SPGDLVWAKM EGYPWWPCLV YNHPFDGTFI 
       130        140        150        160        170        180 
RKKGKSVRVH VQFFDDSPTR GWVSKRMLKP YTGSKSKEAQ KGGHFYSSKS EILRAMQRAD 
       190        200        210        220        230        240 
EALSKDTAER LQLAVCDEPS EPEEEEETEV HEAYLSDKSE EDNYNESEEE AQPSVQGPRR 
       250        260        270        280        290        300 
SSRQVKKRRV ISDSESDIGG SDVEFKPDTK QEGSSDDASS GVGDSDSEDL GTFGKGAPKR 
       310        320        330        340        350        360 
KRAMVAQGGL RRKSLKKETG SAKRATPILS ETKSTLSAFS APQNSESQTH VSGGGNDSSG 
       370        380        390        400        410        420 
PTVWYHETLE WLKPEKRRDE HRRRPDHPEF NPTTLYVPEE FLNSCTPGMR KWWQLKSQNF 
       430        440        450        460        470        480 
DLVIFYKVGK FYELYHMDAV IGVSELGLIF MKGNWAHSGF PEIAFGRFSD SLVQKGYKVA 
       490        500        510        520        530        540 
RVEQTETPEM MEARCRKMAH VSKFDRVVRR EICRIITKGT QTYSVLDGDP SENYSRYLLS 
       550        560        570        580        590        600 
LKEKEEETSG HTRVYGVCFV DTSLGKFFIG QFSDDRHCSR FRTLVAHYPP VQILFEKGNL 
       610        620        630        640        650        660 
STETKTVLKG SLSSCLQEGL IPGSQFWDAT KTLRTLLEGG YFTGNGDSST VLPLVLKGMT 
       670        680        690        700        710        720 
SESDSVGLTP GEESELALSA LGGIVFYLKK CLIDQELLSM ANFEEYFPLD SDTVSTVKPG 
       730        740        750        760        770        780 
AVFTKASQRM VLDAVTLNNL EIFLNGTNGS TEGTLLERLD TCHTPFGKRL LKQWLCAPLC 
       790        800        810        820        830        840 
SPSAISDRLD AVEDLMAVPD KVTEVADLLK KLPDLERLLS KIHNVGSPLK SQNHPDSRAI 
       850        860        870        880        890        900 
MYEETTYSKK KIIDFLSALE GFKVMCKVSG LLEEVAGGFT SKTLKQVVTL QSKSPKGRFP 
       910        920        930        940        950        960 
DLTAELQRWD TAFDHEKARK TGLITPKAGF DSDYDQALAD IRENEQSLLE YLDKQRSRLG 
       970        980        990       1000       1010       1020 
CKSIVYWGIG RNRYQLEIPE NFATRNLPEE YELKSTKKGC KRYWTKTIEK KLANLINAEE 
      1030       1040       1050       1060       1070       1080 
RRDTSLKDCM RRLFCNFDKN HKDWQSAVEC IAVLDVLLCL ANYSQGGDGP MCRPEIVLPG 
      1090       1100       1110       1120       1130       1140 
EDTHPFLEFK GSRHPCITKT FFGDDFIPND ILIGCEEEAE EHGKAYCVLV TGPNMGGKST 
      1150       1160       1170       1180       1190       1200 
LIRQAGLLAV MAQLGCYVPA EKCRLTPVDR VFTRLGASDR IMSGESTFFV ELSETASILR 
      1210       1220       1230       1240       1250       1260 
HATAHSLVLV DELGRGTATF DGTAIANAVV KELAETIKCR TLFSTHYHSL VEDYSKSVCV 
      1270       1280       1290       1300       1310       1320 
RLGHMACMVE NECEDPSQET ITFLYKFIKG ACPKSYGFNA ARLANLPEEV IQKGHRKARE 
      1330       1340       1350    
FERMNQSLQL FREVCLATEK PTINGEAIHR LLALINGL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)