O35381: Acidic leucine-rich nuclear phosphoprotein 32 family member A

General Information

Protein names	- Acidic leucine-rich nuclear phosphoprotein 32 family member A - Acidic nuclear phosphoprotein pp32 - Leucine-rich acidic nuclear protein - LANP - Potent heat-stable protein phosphatase 2A inhibitor I1PP2A
Gene names	Anp32a
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O35381

7 N-termini

8 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEMDKRIYLE LRNRTPSDVK ELVLDNCKSI EGKIEGLTDE FEELEFLSTI NVGLTSISNL
        70         80         90        100        110        120
PKLNKLKKLE LSENRISGDL EVLAEKCPNL KHLNLSGNKI KDLSTIEPLK KLENLKSLDL
       130        140        150        160        170        180
FNCEVTNLNA YRENVFKLLP QVMYLDGYDR DNKEAPDSDV EGYVEDDDEE DEDEEEYDEY
       190        200        210        220        230        240
AQLVEDEEEE DEEEEGEEED VSGEEEEDEE GYNDGEVDDE EDEEEAGEEE GSQKRKREPD

DEGEEDD

Isoforms

Sequence View

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Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 8 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O35381-1-unknown	MEMDKR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O35381-24-unknown	LDNCKS...	24	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
O35381-121-unknown	FNCEVT...	121	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29520
O35381-214-unknown	DGEVDD...	214	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32605
O35381-217-unknown	VDDEED...	217	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32288
O35381-219-unknown	DEEDEE...	219	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32289
O35381-221-unknown	EDEEEA...	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32290

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KSLDLF	120	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29520
...LLPQVM	142	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115293
...DEEEEG	195	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123574
...EEGYND	213	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32605
...YNDGEV	216	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32288
...DGEVDD	218	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32289
...EVDDEE	220	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32290
...GEEDD	247	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	120	LDLF.\|.FNCE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> AN32A_MOUSE @120
GRAC_MOUSE	213	GYND.\|.DGEV	inferred from experiment	unknown	MEROPS	Bird PI	Kaiserman D et al.:Structure of granzyme C reveals... (S01.137)	19299505,
GRAB_MOUSE	216	DGEV.\|.VDDE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_MOUSE	218	EVDD.\|.DEED	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_MOUSE	220	DDEE.\|.EDEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)