Q80TR8: DDB1- and CUL4-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4B6}
Protein names | - DDB1- and CUL4-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4B6} - Serine/threonine-protein kinase VPRBP - 2.7.11.1 |
---|---|
Gene names | Vprbp |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q80TR8 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
Isoforms
- Isoform 2 of Protein VPRBP - Isoform 3 of Protein VPRBP - Isoform 4 of Protein VPRBP - Isoform 2 of DDB1- and CUL4-associated factor 1 - Isoform 3 of DDB1- and CUL4-associated factor 1 - Isoform 4 of DDB1- and CUL4-associated factor 1Sequence View
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
10 20 30 40 50 60
MTTVVVHVDS KAELTTLLEQ WEKDHGSGQD MVPILTRMSE LIEKETEEYR KGDPDPFDDR
70 80 90 100 110 120
HPGRADPECM LGHLLRILFK NDDFMNALVN AYVMTSREPP LNTAACRLLL DIMPGLETAV
130 140 150 160 170 180
VFQEKEGIVE NLFKWAREAD QPLRTYSTGL LGGAMENQDI AANYRDENSQ LVAIVLRRLR
190 200 210 220 230 240
ELQLQEVALR QDSKRPSPRK LSSEPLLPLD EEAVDMDYGD MAVDVVDGEQ ESSRDMEISF
250 260 270 280 290 300
RLDSSHKTSS RVNSATKPEE GGLKKNKSAK HGDRENFRKA KQKLGFSSSD PDRVFVELSN
310 320 330 340 350 360
SSWSEMSPWV IGTNYTLYPM TPAIEQRLIL QYLTPLGEYQ ELLPIFMQLG SRELMMFYID
370 380 390 400 410 420
LKQTNDVLLT FEALKHLASL LLHNKFATEF VAHGGVQKLL EIPRPSMAAT GVSMCLYYLS
430 440 450 460 470 480
YNQDAMERVC MHPHNVLSDV VNYTLWLMEC SHASGCCHAT MFFSICFSFR AVLELFDRYD
490 500 510 520 530 540
GLRRLVNLIS TLEILNLEDQ GALLSDDEIF ASRQTGKHTC MALRKYFEAH LAIKLEQVKQ
550 560 570 580 590 600
SLQRTEGGIL VHPQPPYKAC SYTHEQIVEM MEFLIEYGPA QLYWEPAEVF LKLSCVQLLL
610 620 630 640 650 660
QLISIACNWK TYYARNDTVR FALDVLAILT VVPKIQLQLA ESVDVLDEAG SAVSTVGISI
670 680 690 700 710 720
ILGVAEGEFF IHDAEIQKSA LQIIINCVCG PDNRISSIGK FISGTPRRKL SQTPKSSEHT
730 740 750 760 770 780
LAKMWNVVQS NNGIKVLLSL LSIKMPITDA DQIRALACKA LVGLSRSSTV RQIISKLPLF
790 800 810 820 830 840
SSCQIQQLMK EPVLQDKRSD HVKFCKYAAE LIERVSGKPL LIGTDVSLAR LQKADVVAQS
850 860 870 880 890 900
RISFPEKELL LLIRNHLISK GLGETATVLT READLPMTAA SHSSAFTPVT AAASPVSLPR
910 920 930 940 950 960
TPRIANGIAS RLGSHATVGA SAPSAPPAHP PPRPPQGSLP LPGPSYAGNS PLIGRISFIR
970 980 990 1000 1010 1020
ERPSPCNGRK IRVLRQKSDH GAYSQSPAIK KQLDRHLPSP PTLDSIITEY LREQHARCKN
1030 1040 1050 1060 1070 1080
PVATCPPFSL FTPHQCPEPK QRRQAPINFT SRLNRRASFP KYGGVDGGCF DRHLIFSRFR
1090 1100 1110 1120 1130 1140
PISVFREANE DESGFTCCAF SARERFLMLG TCTGQLKLYN VFSGQEEASY NCHNSAITHL
1150 1160 1170 1180 1190 1200
EPSRDGSLLL TSATWSQPLS ALWGMKSVFD MKHSFTEDHY VEFSKHSQDR VIGTKGDIAH
1210 1220 1230 1240 1250 1260
IYDIQTGNKL LTLFNPDLAN NYKRNCATFN PTDDLVLNDG VLWDVRSAQA IHKFDKFNMN
1270 1280 1290 1300 1310 1320
ISGVFHPNGL EVIINTEIWD LRTFHLLHTV PALDQCRVVF NHTGTVMYGA MLQADDEDDL
1330 1340 1350 1360 1370 1380
LEERMKSPFG SSFRTFNATD YKPIATIDVK RNIFDLCTDT KDCYLAVIEN QGSMDALNMD
1390 1400 1410 1420 1430 1440
TVCRLYEVGR QRLAEDEDEE EDQEEEEQEE EDDDEDDDDT DDLDELDTDQ LLEAELEEDD
1450 1460 1470 1480 1490 1500
NNENAGEDGD NDFSPSDEEL ANLLEEGEEG EDEDSDADEE VELILGDTDS SDNSDLEDDI
ILSLNE
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q80TR8-1-unknown | MTTVVV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q80TR8-1-unknown | MTTVVV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94261 | |||
Q80TR8-1-unknown | MTTVVV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94262 | |||
Q80TR8-1-unknown | MTTVVV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94263 | |||
Q80TR8-218-unknown | YGDMAV... | 218 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32497 | |||
Q80TR8-218-unknown | YGDMAV... | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147293 | |||
Q80TR8-218-unknown | YGDMAV... | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147294 | |||
Q80TR8-218-unknown | YGDMAV... | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147295 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...AVDMDY | 217 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32497 | |||
...AVDMDY | 217 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130636 | |||
...AVDMDY | 217 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130637 | |||
...AVDMDY | 217 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130638 | |||
...LSLNE | 1506 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...LSLNE | 1506 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89879 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_MOUSE | 217 | DMDY.|.YGDM | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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