P14211: Calreticulin

General Information

Protein names	- Calreticulin - CRP55 - Calregulin - Endoplasmic reticulum resident protein 60 - ERp60 - HACBP
Gene names	Calr
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P14211

10 N-termini

7 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLLSVPLLLG LLGLAAADPA IYFKEQFLDG DAWTNRWVES KHKSDFGKFV LSSGKFYGDL
        70         80         90        100        110        120
EKDKGLQTSQ DARFYALSAK FEPFSNKGQT LVVQFTVKHE QNIDCGGGYV KLFPSGLDQK
       130        140        150        160        170        180
DMHGDSEYNI MFGPDICGPG TKKVHVIFNY KGKNVLINKD IRCKDDEFTH LYTLIVRPDN
       190        200        210        220        230        240
TYEVKIDNSQ VESGSLEDDW DFLPPKKIKD PDAAKPEDWD ERAKIDDPTD SKPEDWDKPE
       250        260        270        280        290        300
HIPDPDAKKP EDWDEEMDGE WEPPVIQNPE YKGEWKPRQI DNPDYKGTWI HPEIDNPEYS
       310        320        330        340        350        360
PDANIYAYDS FAVLGLDLWQ VKSGTIFDNF LITNDEAYAE EFGNETWGVT KAAEKQMKDK
       370        380        390        400        410
QDEEQRLKEE EEDKKRKEEE EAEDKEDDDD RDEDEDEEDE KEEDEEESPG QAKDEL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14211-18-unmodified	DPAIYF...	18		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P14211-18-unmodified	DPAIYF...	18		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P14211-18-unknown	DPAIYF...	18	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14211-22-unknown	YFKEQF...	22	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33362
P14211-31-unknown	DAWTNR...	31	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P14211-50-unknown	VLSSGK...	50	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29715
P14211-52-unknown	SSGKFY...	52	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29716
P14211-60-unknown	LEKDKG...	60	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33363
P14211-64-unknown	KGLQTS...	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32312
P14211-133-unknown	GPDICG...	133	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P14211-208-unknown	IKDPDA...	208	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33364

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ADPAIY	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33362
...DFGKFV	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29715
...GKFVLS	51	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29716
...KFYGDL	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33363
...DLEKDK	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32312
...LPPKKI	207	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33364
...AKDEL	416	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	21	PAIY.\|.YFKE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	49	GKFV.\|.VLSS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CALR_MOUSE @49
CATE_MOUSE	51	FVLS.\|.SSGK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CALR_MOUSE @51
MMP2_MOUSE	59	YGDL.\|.LEKD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
GRAB_MOUSE	63	EKDK.\|.KGLQ	inferred from experiment	unknown	MEROPS	Ley TJ	Bredemeyer AJ et al.:A proteomic approach for the di... (S01.136)	15280543,
MMP2_MOUSE	207	PKKI.\|.IKDP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)