P49718: DNA replication licensing factor MCM5 {ECO:0000250|UniProtKB:P33992}
| Protein names | - DNA replication licensing factor MCM5 {ECO:0000250|UniProtKB:P33992} - 3.6.4.12 - CDC46 homolog {ECO:0000303|PubMed:7610039} - P1-CDC46 {ECO:0000250|UniProtKB:P33992} |
|---|---|
| Gene names | Mcm5 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P49718 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSGFDDPGIF YSDSFGGDPG AEEGQARKSQ LQRRFKEFLR QYRVGTDRTG FTFKYRDELK
70 80 90 100 110 120
RHYNLGEYWI EVEMEDLASF DEELADHLHK QPAEHLQLLE EAAKEVADEV TRPRPAGDEL
130 140 150 160 170 180
LQDIQVMLKS DASPSSIRIL KSDMMSHLVK IPGIIISASA VRAKATRISI QCRSCHNTLT
190 200 210 220 230 240
NIAMRPGLEG YALPRKCNMD QAGRPKCPLD PYFIMPDKCK CVDFQTLKLQ ELPDAVPHGE
250 260 270 280 290 300
MPRHMQLYCD RYLCDKVVPG NRVTIMGIYS IKKFGLNPSK GRDRVGVGIR SSYIRVLGIQ
310 320 330 340 350 360
VDTDGSGRSF AGSVSPQEEE EFRRLAALPN IYELISKSIS PSIFGGMDMK KAIACLLFGG
370 380 390 400 410 420
SRKRLPDGLT RRGDINLLML GDPGTAKSQL LKFVEKCSPI GVYTSGKGSS AAGLTASVIR
430 440 450 460 470 480
DPSSRNFIME GGAMVLADGG VVCIDEFDKM REDDRVAIHE AMEQQTISIA KAGITTTLNS
490 500 510 520 530 540
RCSVLAAANS VFGRWDETKG EDNIDFMPTI LSRFDMIFIV KDEHNEERDM MLAKHVMTLH
550 560 570 580 590 600
VSALTQTQAV EGEIDLAKMK KFIAYCRARC GPRLSAEAAE KLKNRYIIMR SGARQHERDS
610 620 630 640 650 660
DRRSSIPITV RQLEAIVRIA EALSKMKLQP FATEADVEEA LRLFQVSTLD AALSGNLSGV
670 680 690 700 710 720
EGFTTQEDQE MLSRIEKQLK RRFAIGSQVS EHSIVQDFTK QKYPEHAIRK VLQLMLRRGE
730
IQHRMQRKVL YRLK
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P49718-2-unknown | MSGFDD... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| P49718-2-unknown | MSGFDD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P49718-2-Acetylation | SGFDDP... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
| P49718-2-Acetylation | SGFDDP... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
| P49718-12-unknown | SDSFGG... | 12 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32609 | |||
| P49718-14-unknown | SFGGDP... | 14 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32349 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PGIFYS | 11 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32609 | |||
| ...IFYSDS | 13 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32349 | |||
| ...VLYRLK | 733 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| GRAC_MOUSE | 11 | IFYS.|.SDSF | inferred from experiment | unknown | MEROPS | Bird PI | Kaiserman D et al.:Structure of granzyme C reveals... (S01.137) | 19299505, |
| GRAB_MOUSE | 13 | YSDS.|.SFGG | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|