P29341: Polyadenylate-binding protein 1

General Information

Protein names	- Polyadenylate-binding protein 1 - PABP-1 - Poly(A)-binding protein 1
Gene names	Pabpc1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P29341

10 N-termini

9 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNPSAPSYPM ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDMITRR SLGYAYVNFQ
        70         80         90        100        110        120
QPADAERALD TMNFDVIKGK PVRIMWSQRD PSLRKSGVGN IFIKNLDKSI DNKALYDTFS
       130        140        150        160        170        180
AFGNILSCKV VCDENGSKGY GFVHFETQEA AERAIEKMNG MLLNDRKVFV GRFKSRKERE
       190        200        210        220        230        240
AELGARAKEF TNVYIKNFGE DMDDERLKEL FGKFGPALSV KVMTDESGKS KGFGFVSFER
       250        260        270        280        290        300
HEDAQKAVDE MNGKELNGKQ IYVGRAQKKV ERQTELKRKF EQMKQDRITR YQGVNLYVKN
       310        320        330        340        350        360
LDDGIDDERL RKEFSPFGTI TSAKVMMEGG RSKGFGFVCF SSPEEATKAV TEMNGRIVAT
       370        380        390        400        410        420
KPLYVALAQR KEERQAHLTN QYMQRMASVR AVPNPVINPY QPAPPSGYFM AAIPQTQNRA
       430        440        450        460        470        480
AYYPPSQIAQ LRPSPRWTAQ GARPHPFQNM PGAIRPAAPR PPFSTMRPAS SQVPRVMSTQ
       490        500        510        520        530        540
RVANTSTQTM GPRPAAAAAA ATPAVRTVPQ YKYAAGVRNP QQHLNAQPQV TMQQPAVHVQ
       550        560        570        580        590        600
GQEPLTASML ASAPPQEQKQ MLGERLFPLI QAMHPSLAGK ITGMLLEIDN SELLHMLESP
       610        620        630
ESLRSKVDEA VAVLQAHQAK EAAQKAVNSA TGVPTV

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 9 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P29341-1-Acetylation	MNPSAP...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P29341-50-unknown	RSLGYA...	50		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P29341-301-unknown	LDDGID...	301		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33514
P29341-320-unknown	ITSAKV...	320		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33515
P29341-338-unknown	VCFSSP...	338		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29916
P29341-340-unknown	FSSPEE...	340		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29917
P29341-341-unknown	SSPEEA...	341		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28861
P29341-341-unknown	SSPEEA...	341		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29918
P29341-549-unknown	MLASAP...	549		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33516
P29341-553-unknown	APPQEQ...	553		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33517
P29341-590-unknown	NSELLH...	590		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32339

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LYVKNL	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33514
...SPFGTI	319	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33515
...KGFGFV	337	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29916
...FGFVCF	339	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29917
...GFVCFS	340	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28861
...GFVCFS	340	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29918
...PLTASM	548	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33516
...SMLASA	552	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33517
...LLEIDN	589	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32339
...GVPTV	636	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	300	VKNL.\|.LDDG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	319	FGTI.\|.ITSA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	337	FGFV.\|.VCFS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PABP1_MOUSE @337
CATE_MOUSE	339	FVCF.\|.FSSP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PABP1_MOUSE @339
CATD_MOUSE	340	VCFS.\|.SSPE	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PABP1_MOUSE @340
CATE_MOUSE	340	VCFS.\|.SSPE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PABP1_MOUSE @340
MMP2_MOUSE	548	TASM.\|.MLAS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	552	LASA.\|.APPQ	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
GRAB_MOUSE	589	EIDN.\|.NSEL	inferred from experiment	unknown	MEROPS	Craik CS	Loeb CR et al.:Granzyme B proteolyzes receptor... (S01.136)	16798735,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)