Q8C1D8: Protein IWS1 homolog

General Information

Protein names	- Protein IWS1 homolog - IWS1-like protein
Gene names	Iws1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8C1D8

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDSEYYSGDQ SDDGGATPVQ DERDSGSDGE DGVTEQHSGS DTGSVDHHSE NETSDREDGL
        70         80         90        100        110        120
AKIHNGTDSE NDEPSNANAS DSESEELHRP KDSDSDSEEH AESPASDSEN EPVNQHGSDS
       130        140        150        160        170        180
ENEELLNGHA SDSEKEEVSK HAASDSEAED TLQPQVSESD SEDPPRPQAS DSENEEPPKP
       190        200        210        220        230        240
RISDSESEEL PKPRVSDSES EDPPRPQASD SESEELPKPR VSDSESEDPP RPQASDSESE
       250        260        270        280        290        300
ELPKPRVSDS ESEDPQKGPA SDSEAEDASR HKEKPDSDDS DGENKREDSE VQNESDGHTD
       310        320        330        340        350        360
RKGLHSSDSE EEEPKRQKID SDDDEEKEGD EEKVAKRKAA VLSDSEDDAG NASAKKSRVV
       370        380        390        400        410        420
CDADDSDSDV VSDKSGKRET TVASDSEEEA GKEESSVKKK EDKDLFGSDS ESGNEEENLI
       430        440        450        460        470        480
ADIFGESGDE EEEEFTGFNQ EDLEEEKNET QLKEAEDSDS DDNIKRGKHM DFLSDFEMML
       490        500        510        520        530        540
QRKKSMCGKR RRNRDGGTFI SDADDVVSAM IVKMNEAAEE DRQLNNQKKP ALKKLTLLPT
       550        560        570        580        590        600
VVMHLKKQDL KETFIDSGVM SAIKEWLSPL PDRSLPALKI REELLKILQE LPSVSQETLK
       610        620        630        640        650        660
HSGIGRAVMY LYKHPKESRS NKDMAGKLIN EWSRPIFGLT SNYKGMTREE REQRDLEQMP
       670        680        690        700        710        720
QRRRLSSTGG QTPRRDLEKV LTGEEKALRP GDPGFCARAR VPMPSNKDYV VRPKWNVEME
       730        740        750        760
SSRFQASSKK GISRLDKQMR KFTDIRKKSR SAHAVKISIE GNKMPL

Isoforms

- Isoform 2 of Protein IWS1 homolog

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8C1D8-1-Acetylation	MDSEYY...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8C1D8-1-Acetylation	MDSEYY...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102651
Q8C1D8-1-unknown	MDSEYY...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78251
Q8C1D8-10-unknown	QSDDGG...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32515
Q8C1D8-10-unknown	QSDDGG...	10		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194859
Q8C1D8-458-unknown	SDSDDN...	458		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32516
Q8C1D8-458-unknown	SDSDDN...	458		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152879

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YYSGDQ	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32515
...KEAEDS	457	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32516
...KEAEDS	457	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136304
...NKMPL	766	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	9	SGDQ.\|.QSDD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_MOUSE	457	AEDS.\|.SDSD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)