P68033: Actin, alpha cardiac muscle 1

General Information

Protein names	- Actin, alpha cardiac muscle 1 - Alpha-cardiac actin - Actin, alpha cardiac muscle 1, intermediate form
Gene names	Actc1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P68033

13 N-termini

14 C-termini

17 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCDDEETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG QKDSYVGDEA
        70         80         90        100        110        120
QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP EEHPTLLTEA PLNPKANREK
       130        140        150        160        170        180
MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VTHNVPIYEG YALPHAIMRL
       190        200        210        220        230        240
DLAGRDLTDY LMKILTERGY SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK
       250        260        270        280        290        300
SYELPDGQVI TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV
       310        320        330        340        350        360
LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS LSTFQQMWIS
       370
KQEYDEAGPS IVHRKCF

Isoforms

Sequence View

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P68033-3-Acetylation	DDEETT...	3	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P68033-3-Acetylation	DDEETT...	3	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P68033-32-unknown	VFPSIV...	32		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33765
P68033-42-unknown	HQGVMV...	42		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33766
P68033-47-unknown	VGMGQK...	47		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30282
P68033-56-unknown	VGDEAQ...	56		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30283
P68033-107-unknown	LTEAPL...	107		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30284
P68033-107-unknown	LTEAPL...	107		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29054
P68033-139-unknown	QAVLSL...	139		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30285
P68033-142-unknown	LSLYAS...	142		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30286
P68033-192-unknown	MKILTE...	192		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30287
P68033-230-unknown	ATAASS...	230		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29055
P68033-247-unknown	GQVITI...	247		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28489
P68033-247-unknown	GQVITI...	247		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32382
P68033-247-unknown	GQVITI...	247		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28568
P68033-247-unknown	GQVITI...	247		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28368
P68033-300-unknown	VLSGGT...	300		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30288
P68033-302-unknown	SGGTTM...	302		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30289
P68033-302-unknown	SGGTTM...	302		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29056

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DAPRAV	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33765
...VGRPRH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33766
...RPRHQG	43	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123370
...HQGVMV	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30282
...QKDSYV	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30283
...EHPTLL	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30284
...EHPTLL	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29054
...MYVAIQ	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30285
...AIQAVL	141	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30286
...LTDYLM	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30287
...FENEMA	229	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29055
...YELPDG	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28489
...YELPDG	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32382
...YELPDG	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28568
...YELPDG	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28368
...LYANNV	299	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30288
...ANNVLS	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30289
...ANNVLS	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29056
...HRKCF	377	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	31	PRAV.\|.VFPS	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> ACTC_MOUSE @31
MMP2_MOUSE	41	RPRH.\|.HQGV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> ACTC_MOUSE @41
CATE_MOUSE	46	GVMV.\|.VGMG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @46
CATE_MOUSE	55	DSYV.\|.VGDE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @55
CATE_MOUSE	106	PTLL.\|.LTEA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @106
CATD_MOUSE	106	PTLL.\|.LTEA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	138	VAIQ.\|.QAVL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @138
CATE_MOUSE	141	QAVL.\|.LSLY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @141
CATE_MOUSE	191	DYLM.\|.MKIL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @191
CATD_MOUSE	229	NEMA.\|.ATAA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CASP3_MOUSE	246	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
GRAB_MOUSE	246	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CASP7_MOUSE	246	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP1_MOUSE	246	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Nunez G	Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001)	18667412,
CATE_MOUSE	299	ANNV.\|.VLSG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @299
CATE_MOUSE	301	NVLS.\|.SGGT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTC_MOUSE @301
CATD_MOUSE	301	NVLS.\|.SGGT	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,

TopFIND

P68033: Actin, alpha cardiac muscle 1

General Information

13

N-termini

14

C-termini

17

Cleavages

0

Substrates

Sequence

Isoforms

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Domains & Features

13 N-termini - 14 C-termini - 17 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates