TopFIND 4.0

P29452: Caspase-1

General Information

Protein names
- Caspase-1
- CASP-1
- 3.4.22.36
- Interleukin-1 beta convertase
- IL-1BC
- Interleukin-1 beta-converting enzyme
- ICE
- IL-1 beta-converting enzyme
- p45
- Caspase-1 subunit p20
- Caspase-1 subunit p10
Gene names Casp1
Organism Mus musculus
Protease Family C14.001
Protease ID C14.001
Chromosome location
UniProt ID P29452

2

N-termini

2

C-termini

0

Cleavages

86

Substrates

Sequence

        10         20         30         40         50         60 
MADKILRAKR KQFINSVSIG TINGLLDELL EKRVLNQEEM DKIKLANITA MDKARDLCDH 
        70         80         90        100        110        120 
VSKKGPQASQ IFITYICNED CYLAGILELQ SAPSAETFVA TEDSKGGHPS SSETKEEQNK 
       130        140        150        160        170        180 
EDGTFPGLTG TLKFCPLEKA QKLWKENPSE IYPIMNTTTR TRLALIICNT EFQHLSPRVG 
       190        200        210        220        230        240 
AQVDLREMKL LLEDLGYTVK VKENLTALEM VKEVKEFAAC PEHKTSDSTF LVFMSHGIQE 
       250        260        270        280        290        300 
GICGTTYSNE VSDILKVDTI FQMMNTLKCP SLKDKPKVII IQACRGEKQG VVLLKDSVRD 
       310        320        330        340        350        360 
SEEDFLTDAI FEDDGIKKAH IEKDFIAFCS STPDNVSWRH PVRGSLFIES LIKHMKEYAW 
       370        380        390        400    
SCDLEDIFRK VRFSFEQPEF RLQMPTADRV TLTKRFYLFP GH

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 86 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P29452-119-unknown NKEDGT... 119 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P29452-315-unknown GIKKAH... 315 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VLLKDS 296 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LFPGH 402 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates