Q9JLQ2: ARF GTPase-activating protein GIT2

General Information

Protein names	- ARF GTPase-activating protein GIT2 - ARF GAP GIT2 - Cool-interacting tyrosine-phosphorylated protein 2 - CAT-2 - CAT2 - G protein-coupled receptor kinase-interactor 2 - GRK-interacting protein 2
Gene names	Git2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9JLQ2

5 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKRLRSSDV CADCNGPDPS WASVNRGTFI CDECCSVHRS LGRHISQVRH LKHTAWPPTL
        70         80         90        100        110        120
LQMVETLYNN GANSIWEHSL LDPASIMSGR RKANPQDKVH PNKAEFIRAK YQMLAFVHRL
       130        140        150        160        170        180
PCREDDSVTA KDLSKQLHSS VRTGNLETCL RLLSLGAQAN FFHPEKGSTP LHVASKAGQI
       190        200        210        220        230        240
LQAELLAVYG ADPGTQDSSG KTPVDYARQG GHHELAERLI EIQYELTDRL AFYLCGRKPD
       250        260        270        280        290        300
HKSGQHFLIP QRADSLDLSE LAKAAKKKLQ SLSNHLFEEL AMDVYDEVDR RETDAVWLAT
       310        320        330        340        350        360
QNHSTLVTET TVVPFLPVNP EYSSTRNQGR QKLARFNAHE FATLVIDILS DAKRRQQGSP
       370        380        390        400        410        420
LSRSKDNVEL ILRTVSTQHS TESQDNDQPD YDSVASDEDT DVETRASKAN RQKLQTLQSE
       430        440        450        460        470        480
NSSLRRQATA SACQVQTGSD HKDTASHSSL KRRPSARGSR PMSMYETGSG QKPYLPMGEA
       490        500        510        520        530        540
SHPEESRTRL QPFPTHIGRS ALVTSSSSLP SFPSTLSWSR DESARRASRL EKQNSTPESD
       550        560        570        580        590        600
YDNTACDPEP DDTGSTRKGR QRSMLWQGDG LLPDTAEPHS VPSPTLPSTE DVIRKTEQIT
       610        620        630        640        650        660
KNIQELLRAA QENKHDSYIP CSERIHVAVT EMAALFPKKP KSDTVRTSLR LLTSSAYRLQ
       670        680        690        700
SECRKALPGD SSLPTDVQLV TQQVIQCAYD IAKAAKQLVT ITTKENSS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9JLQ2-1-unknown	MSKRLR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9JLQ2-19-unknown	PSWASV...	19	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9JLQ2-29-unknown	FICDEC...	29	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122302
Q9JLQ2-112-unknown	QMLAFV...	112	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118812
Q9JLQ2-391-unknown	YDSVAS...	391	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28419

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPVDYA	206	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116722
...KRRQQG	357	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118812
...NDQPDY	390	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28419
...PEPDDT	552	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115185
...KENSS	708	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP1_MOUSE	390	QPDY.\|.YDSV	inferred from experiment	unknown	MEROPS	Nunez G	Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001)	18667412,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)