O35601: FYN-binding protein 1

General Information

Protein names	- FYN-binding protein 1 - Adhesion and degranulation promoting adaptor protein - ADAP - FYB-120/130 - p120/p130 - FYN-T-binding protein - SLAP-130 - SLP-76-associated phosphoprotein
Gene names	Fyb
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O35601

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform FYB-120 of FYN-binding protein - Isoform FYB-120 of FYN-binding protein 1

Sequence View

        10         20         30         40         50         60
MAKFNTGSNP TEEAATSSRP FKVAGQSSPS GIQSRKNLFD NQGNASPPAG PSSMPKFGTT
        70         80         90        100        110        120
KPPLAAKPTY EEKPEKEPKP PFLKPTGGSP RFGTQPNSVS RDPEVKVGFL KPVSPKPTSL
       130        140        150        160        170        180
TKEDSKPVVL RPPGNKLHNL NQESDLKTPG PKPGPAPPVP ENELKPGFSK VAGAKSKFMP
       190        200        210        220        230        240
AAQDTDSKPR FPRHTFGQKP SLSTEDSQEE NTSKNVPVQK GSPVQLGAKS KGAPFKPPKE
       250        260        270        280        290        300
DPEDKDHGAP SSPFPGVVLK PAASRGSPGL SKNFEEKKED RKTDLAKNIF LNKLNQEEPA
       310        320        330        340        350        360
RFPKAPSKLT AGTPWGQSQE KEGDKNSATP KQKALPPLSV LGPPPPKPNR PPNVDLTRFR
       370        380        390        400        410        420
KADSANSATK SQTPYSTTSL PPPPPTHPAS QPPLPASHPA HPPVPSLPPR NIKPPLDLKH
       430        440        450        460        470        480
PINDENQDGV MHSDGTGNLE EEQESEGETY EDIDSSKERD KKREKEEKKR LELERKEQKE
       490        500        510        520        530        540
REKKEQELKK KFKLTGPIQV IHHAKACCDV KGGKNELSFK QGEDIEIIRI TDNPEGKWLG
       550        560        570        580        590        600
RTARGSYGYI KTTAVEIDYD SLKRKKNSLN AVPPRLVEDD QDVYDDVAEQ DAPNSHGQSG
       610        620        630        640        650        660
SGGMFPPPPT DDEIYDGIEE EDDDDGSVPQ VDEKTNAWSW GILKMLKGKD DRKKSIREKP
       670        680        690        700        710        720
KVSESDNNEG SSLPSQHKQL DVGEEVYDDV DASDFPPPPA EMSQGMSVGR AKTEEKDPKK
       730        740        750        760        770        780
LKKQEKEEKD LRKKFKYDGE IRVLYSTKVA SSLTSKKWGA RDLQIKPGES LEVIQSTDDT
       790        800        810
KVLCRNEEGK YGYVLRSYLV DNDGEIYDDI ADGCIYDND         10         20         30         40         50         60
MAKFNTGSNP TEEAATSSRP FKVAGQSSPS GIQSRKNLFD NQGNASPPAG PSSMPKFGTT
        70         80         90        100        110        120
KPPLAAKPTY EEKPEKEPKP PFLKPTGGSP RFGTQPNSVS RDPEVKVGFL KPVSPKPTSL
       130        140        150        160        170        180
TKEDSKPVVL RPPGNKLHNL NQESDLKTPG PKPGPAPPVP ENELKPGFSK VAGAKSKFMP
       190        200        210        220        230        240
AAQDTDSKPR FPRHTFGQKP SLSTEDSQEE NTSKNVPVQK GSPVQLGAKS KGAPFKPPKE
       250        260        270        280        290        300
DPEDKDHGAP SSPFPGVVLK PAASRGSPGL SKNFEEKKED RKTDLAKNIF LNKLNQEEPA
       310        320        330        340        350        360
RFPKAPSKLT AGTPWGQSQE KEGDKNSATP KQKALPPLSV LGPPPPKPNR PPNVDLTRFR
       370        380        390        400        410        420
KADSANSATK SQTPYSTTSL PPPPPTHPAS QPPLPASHPA HPPVPSLPPR NIKPPLDLKH
       430        440        450        460        470        480
PINDENQDGV MHSDGTGNLE EEQESEGETY EDIDSSKERD KKREKEEKKR LELERKEQKE
       490        500        510        520        530        540
REKKEQELKK KFKLTGPIQV IHHAKACCDV KGGKNELSFK QGEDIEIIRI TDNPEGKWLG
       550        560        570        580        590        600
RTARGSYGYI KTTAVEIDYD SLKRKKNSLN AVPPRLVEDD QDVYDDVAEQ DAPNSHGQSG
       610        620        630        640        650        660
SGGMFPPPPT DDEIYDGIEE EDDDDGSVPQ VDEKTNAWSW GILKMLKGKD DRKKSIREKP
       670        680        690        700        710        720
KVSESDNNEG SSLPSQHKQL DVGEEVYDDV DASDFPPPPA EMSQGMSVGR AKTEEKDPKK
       730        740        750        760        770        780
LKKQEKEEKD LRKKFKYDGE IRVLYSTKVA SSLTSKKWGA RDLQIKPGES LEVIQSTDDT
       790        800        810
KVLCRNEEGK YGYVLRSYLV DNDGEIYDDI ADGCIYDND

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O35601-1-unknown	MAKFNT...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75608
O35601-1-unknown	MAKFNT...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O35601-2-unknown	MAKFNT...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
O35601-2-Acetylation	AKFNTG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O35601-2-Acetylation	AKFNTG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111538
O35601-2-Acetylation	AKFNTG...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
O35601-435-unknown	GTGNLE...	435		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28341
O35601-435-unknown	GTGNLE...	435		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152558
O35601-772-unknown	EVIQST...	772		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29522
O35601-772-unknown	EVIQST...	772		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156109

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VMHSDG	434	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28341
...VMHSDG	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135972
...PGESLE	771	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29522
...PGESLE	771	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139572
...IYDND	819	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IYDND	819	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71226

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP1_MOUSE	434	HSDG.\|.GTGN	inferred from experiment	unknown	MEROPS	Nunez G	Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001)	18667412,
CATE_MOUSE	771	ESLE.\|.EVIQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> FYB_MOUSE @771

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)