P17427: AP-2 complex subunit alpha-2
| Protein names | - AP-2 complex subunit alpha-2 - 100 kDa coated vesicle protein C - Adaptor protein complex AP-2 subunit alpha-2 - Adaptor-related protein complex 2 subunit alpha-2 - Alpha-adaptin C - Alpha2-adaptin - Clathrin assembly protein complex 2 alpha-C large chain - Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit |
|---|---|
| Gene names | Ap2a2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P17427 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPAVSKGDGM RGLAVFISDI RNCKSKEAEI KRINKELANI RSKFKGDKAL DGYSKKKYVC
70 80 90 100 110 120
KLLFIFLLGH DIDFGHMEAV NLLSSNRYTE KQIGYLFISV LVNSNSELIR LINNAIKNDL
130 140 150 160 170 180
ASRNPTFMGL ALHCIANVGS REMAEAFAGE IPKILVAGDT MDSVKQSAAL CLLRLYRTSP
190 200 210 220 230 240
DLVPMGDWTS RVVHLLNDQH LGVVTAATSL ITTLAQKNPE EFKTSVSLAV SRLSRIVTSA
250 260 270 280 290 300
STDLQDYTYY FVPAPWLSVK LLRLLQCYPP PDPAVRGRLT ECLETILNKA QEPPKSKKVQ
310 320 330 340 350 360
HSNAKNAVLF EAISLIIHHD SEPNLLVRAC NQLGQFLQHR ETNLRYLALE SMCTLASSEF
370 380 390 400 410 420
SHEAVKTHIE TVINALKTER DVSVRQRAVD LLYAMCDRSN AQQIVAEMLS YLETADYSIR
430 440 450 460 470 480
EEIVLKVAIL AEKYAVDYTW YVDTILNLIR IAGDYVSEEV WYRVIQIVIN RDDVQGYAAK
490 500 510 520 530 540
TVFEALQAPA CHENLVKVGG YILGEFGNLI AGDPRSSPLI QFNLLHSKFH LCSVPTRALL
550 560 570 580 590 600
LSTYIKFVNL FPEVKATIQD VLRSDSQLKN ADVELQQRAV EYLRLSTVAS TDILATVLEE
610 620 630 640 650 660
MPPFPERESS ILAKLKKKKG PSTVTDLEET KRERSIDVNG GPEPVPASTS AASTPSPSAD
670 680 690 700 710 720
LLGLGAVPPA PTGPPPSSGG GLLVDVFSDS ASAVAPLAPG SEDNFARFVC KNNGVLFENQ
730 740 750 760 770 780
LLQIGLKSEF RQNLGRMFIF YGNKTSTQFL NFTPTLICAD DLQTNLNLQT KPVDPTVDGG
790 800 810 820 830 840
AQVQQVVNIE CISDFTEAPV LNIQFRYGGT FQNVSVKLPI TLNKFFQPTE MASQDFFQRW
850 860 870 880 890 900
KQLSNPQQEV QNIFKAKHPM DTEITKAKII GFGSALLEEV DPNPANFVGA GIIHTKTTQI
910 920 930
GCLLRLEPNL QAQMYRLTLR TSKDTVSQRL CELLSEQF
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P17427-2-unknown | PAVSKG... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P17427-2-unknown | PAVSKG... | 2 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| P17427-227-unknown | SLAVSR... | 227 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| P17427-694-unknown | VAPLAP... | 694 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28349 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...DSASAV | 693 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28349 | |||
| ...LSEQF | 938 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CASP1_MOUSE | 693 | ASAV.|.VAPL | inferred from experiment | unknown | MEROPS | Nunez G | Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001) | 18667412, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|