Q99KY4: Cyclin-G-associated kinase

General Information

Protein names	- Cyclin-G-associated kinase - 2.7.11.1
Gene names	Gak
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99KY4

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLLQSALDF LAGPGSLGGA AGRDQSDFVG QTVELGELRL RVRRVLAEGG FAFVYEAQDL
        70         80         90        100        110        120
GSGREYALKR LLSNEEEKNR AIIQEVCFLK KLSGHPNIVQ FCSAASIGKE ESDTGQAEFL
       130        140        150        160        170        180
LLTELCKGQL VEFLKRVECK GPLSCDSILK IFYQTCRAVQ HMHRQKPPII HRDLKVENLL
       190        200        210        220        230        240
LSNQGTIKLC DFGSATTISH YPDYSWSAQK RAMVEEEITR NTTPMYRTPE IVDLYSNFPI
       250        260        270        280        290        300
GEKQDIWALG CILYLLCFRQ HPFEDGAKLR IVNGKYSIPV NDTRYTVFHD LIRAMLKVNP
       310        320        330        340        350        360
VERLSIAEVV RQLQEIAAAR NVNPKAPITE LLEQNGGYGN SGPSRAQPPC GGTVNSSGVL
       370        380        390        400        410        420
ALAEYDQPYG GFLDILRGGT ERLFTNLKDT SSKVIQSVAN YAKGDLDISY ITSRIAVMSF
       430        440        450        460        470        480
PAEGVESAIK NNIEDVRMFL DAKHPGHYAV YNLSPRIYRA SKFHNRVTEC GWAVRRAPHL
       490        500        510        520        530        540
HSLYTLCRSM HAWLREDHRN VCVVHCMDGR AASAVAVCAF LCFCRLFSTA EAAVYMFSMK
       550        560        570        580        590        600
RCPPGIWPSH KRYIEYVCDM VAEEPITPHS KPMLVKSVVM TPVPLFSKQR NGCRPFCEVY
       610        620        630        640        650        660
VGEERVTTTS QEYDRMKEFK IEDGKAVIPL GVTVQGDVLI IIYHARATLG GRLQAKMASM
       670        680        690        700        710        720
KMFQIQFHTG FVPRNATTVK FAKYDLDACD IQEKYPDLFQ VNLEVEVEPR DRPSREAPPW
       730        740        750        760        770        780
ENTSLRGLNP KILFSNREEQ QDILSKFGKP ELPRQPGSTA QYDAEAGSPE AEITESDSPQ
       790        800        810        820        830        840
SSSTDTNHFL HTLDWQEEKE PETGLDNTSP KESQSVLIAD GDGSEVSDEE EASFPSEERK
       850        860        870        880        890        900
PGAGEDTPRL AAGTKQQDLI FDVGMLAAPQ EPVQPEEGVD LLGLHSEGDL RPAAPLQACG
       910        920        930        940        950        960
VPSSNTDLLS CLLEPSDAAQ VGPPGDLLGG EAPLLLASPV SPLGLQNNLQ GKVPDTVDPF
       970        980        990       1000       1010       1020
DQFLLSSNSD TQPCSKPDLF GEFLNSDSVA SSTAFPSTHS APPPSCSTAF LHLGDLPAEP
      1030       1040       1050       1060       1070       1080
SKVIASSSHP DLLGGWDTWA DTATPGPASI PVPEGTLFSS AGHPAPPGPN PSQTKSQNLD
      1090       1100       1110       1120       1130       1140
PFADLSDLSS SLQGLPAGLP AGGFVGAPAP TQKSNSPWQA NRPTAPGTSW TPQAKPAPRA
      1150       1160       1170       1180       1190       1200
SEQLRSHFSV IGAREERGVR VPSFAQKPKV SENDFEDLLP NQGFSKSDKK GPKTMAEMRK
      1210       1220       1230       1240       1250       1260
QELARDTDPL KLKLLDWIEG KERNIRALLS TLHTVLWDGE SRWTPVSMAD LVTPEQVKKQ
      1270       1280       1290       1300
YRRAVLVVHP DKATGQPYEQ YAKMIFMELN DAWSEFENQG SRPLF

Isoforms

- Isoform 2 of Cyclin-G-associated kinase

Sequence View

        10         20         30         40         50         60
MSLLQSALDF LAGPGSLGGA AGRDQSDFVG QTVELGELRL RVRRVLAEGG FAFVYEAQDL
        70         80         90        100        110        120
GSGREYALKR LLSNEEEKNR AIIQEVCFLK KLSGHPNIVQ FCSAASIGKE ESDTGQAEFL
       130        140        150        160        170        180
LLTELCKGQL VEFLKRVECK GPLSCDSILK IFYQTCRAVQ HMHRQKPPII HRDLKVENLL
       190        200        210        220        230        240
LSNQGTIKLC DFGSATTISH YPDYSWSAQK RAMVEEEITR NTTPMYRTPE IVDLYSNFPI
       250        260        270        280        290        300
GEKQDIWALG CILYLLCFRQ HPFEDGAKLR IVNGKYSIPV NDTRYTVFHD LIRAMLKVNP
       310        320        330        340        350        360
VERLSIAEVV RQLQEIAAAR NVNPKAPITE LLEQNGGYGN SGPSRAQPPC GGTVNSSGVL
       370        380        390        400        410        420
ALAEYDQPYG GFLDILRGGT ERLFTNLKDT SSKVIQSVAN YAKGDLDISY ITSRIAVMSF
       430        440        450        460        470        480
PAEGVESAIK NNIEDVRMFL DAKHPGHYAV YNLSPRIYRA SKFHNRVTEC GWAVRRAPHL
       490        500        510        520        530        540
HSLYTLCRSM HAWLREDHRN VCVVHCMDGR AASAVAVCAF LCFCRLFSTA EAAVYMFSMK
       550        560        570        580        590        600
RCPPGIWPSH KRYIEYVCDM VAEEPITPHS KPMLVKSVVM TPVPLFSKQR NGCRPFCEVY
       610        620        630        640        650        660
VGEERVTTTS QEYDRMKEFK IEDGKAVIPL GVTVQGDVLI IIYHARATLG GRLQAKMASM
       670        680        690        700        710        720
KMFQIQFHTG FVPRNATTVK FAKYDLDACD IQEKYPDLFQ VNLEVEVEPR DRPSREAPPW
       730        740        750        760        770        780
ENTSLRGLNP KILFSNREEQ QDILSKFGKP ELPRQPGSTA QYDAEAGSPE AEITESDSPQ
       790        800        810        820        830        840
SSSTDTNHFL HTLDWQEEKE PETGLDNTSP KESQSVLIAD GDGSEVSDEE EASFPSEERK
       850        860        870        880        890        900
PGAGEDTPRL AAGTKQQDLI FDVGMLAAPQ EPVQPEEGVD LLGLHSEGDL RPAAPLQACG
       910        920        930        940        950        960
VPSSNTDLLS CLLEPSDAAQ VGPPGDLLGG EAPLLLASPV SPLGLQNNLQ GKVPDTVDPF
       970        980        990       1000       1010       1020
DQFLLSSNSD TQPCSKPDLF GEFLNSDSVA SSTAFPSTHS APPPSCSTAF LHLGDLPAEP
      1030       1040       1050       1060       1070       1080
SKVIASSSHP DLLGGWDTWA DTATPGPASI PVPEGTLFSS AGHPAPPGPN PSQTKSQNLD
      1090       1100       1110       1120       1130       1140
PFADLSDLSS SLQGLPAGLP AGGFVGAPAP TQKSNSPWQA NRPTAPGTSW TPQAKPAPRA
      1150       1160       1170       1180       1190       1200
SEQLRSHFSV IGAREERGVR VPSFAQKPKV SENDFEDLLP NQGFSKSDKK GPKTMAEMRK
      1210       1220       1230       1240       1250       1260
QELARDTDPL KLKLLDWIEG KERNIRALLS TLHTVLWDGE SRWTPVSMAD LVTPEQVKKQ
      1270       1280       1290       1300
YRRAVLVVHP DKATGQPYEQ YAKMIFMELN DAWSEFENQG SRPLF

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q99KY4-1-unknown	MSLLQS...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75673
Q99KY4-2-unknown	MSLLQS...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q99KY4-2-unknown	MSLLQS...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99KY4-2-Acetylation	SLLQSA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99KY4-2-Acetylation	SLLQSA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110617
Q99KY4-2-Acetylation	SLLQSA...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q99KY4-821-unknown	GDGSEV...	821		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28414
Q99KY4-821-unknown	GDGSEV...	821		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156377

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VLIADG	820	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28414
...VLIADG	820	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139856
...SRPLF	1305	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SRPLF	1305	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71291

TopFIND

Q99KY4: Cyclin-G-associated kinase

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates