P47713: Cytosolic phospholipase A2
| Protein names | - Cytosolic phospholipase A2 - cPLA2 - Phospholipase A2 group IVA - Phospholipase A2 - 3.1.1.4 - Phosphatidylcholine 2-acylhydrolase - Lysophospholipase - 3.1.1.5 |
|---|---|
| Gene names | Pla2g4a |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P47713 |
2
N-termini
2
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSFIDPYQHI IVEHQYSHKF TVVVLRATKV TKGTFGDMLD TPDPYVELFI STTPDSRKRT
70 80 90 100 110 120
RHFNNDINPV WNETFEFILD PNQENVLEIT LMDANYVMDE TLGTATFPVS SMKVGEKKEV
130 140 150 160 170 180
PFIFNQVTEM ILEMSLEVCS CPDLRFSMAL CDQEKTFRQQ RKENIKENMK KLLGPKKSEG
190 200 210 220 230 240
LYSTRDVPVV AILGSGGGFR AMVGFSGVMK ALYESGILDC ATYIAGLSGS TWYMSTLYSH
250 260 270 280 290 300
PDFPEKGPEE INEELMKNVS HNPLLLLTPQ KVKRYVESLW KKKSSGQPVT FTDIFGMLIG
310 320 330 340 350 360
ETLIQNRMSM TLSSLKEKVN AARCPLPLFT CLHVKPDVSE LMFADWVEFS PYEIGMAKYG
370 380 390 400 410 420
TFMAPDLFGS KFFMGTVVKK YEENPLHFLM GVWGSAFSIL FNRVLGVSGS QNKGSTMEEE
430 440 450 460 470 480
LENITAKHIV SNDSSDSDDE AQGPKGTENE EAEKEYQSDN QASWVHRMLM ALVSDSALFN
490 500 510 520 530 540
TREGRAGKVH NFMLGLNLNT SYPLSPLRDF SSQDSFDDEL DAAVADPDEF ERIYEPLDVK
550 560 570 580 590 600
SKKIHVVDSG LTFNLPYPLI LRPQRGVDLI ISFDFSARPS DTSPPFKELL LAEKWAKMNK
610 620 630 640 650 660
LPFPKIDPYV FDREGLKECY VFKPKNPDVE KDCPTIIHFV LANINFRKYK APGVLRETKE
670 680 690 700 710 720
EKEIADFDIF DDPESPFSTF NFQYPNQAFK RLHDLMYFNT LNNIDVIKDA IVESIEYRRQ
730 740
NPSRCSVSLS NVEARKFFNK EFLSKPTV
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P47713-1-unknown | MSFIDP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P47713-522-unknown | AAVADP... | 522 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28465 | |||
| P47713-522-unknown | AAVADP... | 522 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28545 | |||
| P47713-522-unknown | AAVADP... | 522 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28356 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...DDELDA | 521 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28465 | |||
| ...DDELDA | 521 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28545 | |||
| ...DDELDA | 521 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28356 | |||
| ...SKPTV | 748 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CASP3_MOUSE | 521 | ELDA.|.AAVA | inferred from experiment | unknown | MEROPS | Vandenabeele P | Demon D et al.:Proteome-wide substrate analysi... (C14.003) | 19759058, |
| CASP7_MOUSE | 521 | ELDA.|.AAVA | inferred from experiment | unknown | MEROPS | Vandenabeele P | Demon D et al.:Proteome-wide substrate analysi... (C14.003) | 19759058, |
| CASP1_MOUSE | 521 | ELDA.|.AAVA | inferred from experiment | unknown | MEROPS | Nunez G | Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001) | 18667412, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|