P97864: Caspase-7
Protein names | - Caspase-7 - CASP-7 - 3.4.22.60 - Apoptotic protease Mch-3 - Cysteine protease LICE2 - Caspase-7 subunit p20 - Caspase-7 subunit p11 |
---|---|
Gene names | Casp7 |
Organism | Mus musculus |
Protease Family | C14.004 |
Protease ID | C14.004 |
Chromosome location | |
UniProt ID | P97864 |
5
N-termini
3
C-termini
3
Cleavages
77
Substrates
Sequence
10 20 30 40 50 60
MTDDQDCAAE LEKVDSSSED GVDAKPDRSS IISSILLKKK RNASAGPVRT GRDRVPTYLY
70 80 90 100 110 120
RMDFQKMGKC IIINNKNFDK ATGMDVRNGT DKDAGALFKC FQNLGFEVTV HNDCSCAKMQ
130 140 150 160 170 180
DLLRKASEED HSNSACFACV LLSHGEEDLI YGKDGVTPIK DLTAHFRGDR CKTLLEKPKL
190 200 210 220 230 240
FFIQACRGTE LDDGIQADSG PINDIDANPR NKIPVEADFL FAYSTVPGYY SWRNPGKGSW
250 260 270 280 290 300
FVQALCSILN EHGKDLEIMQ ILTRVNDRVA RHFESQSDDP RFNEKKQIPC MVSMLTKELY
FSR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 3 C-termini - 3 Cleavages - 77 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P97864-2-Acetylation | MTDDQD... | 1 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
P97864-2-unknown | TDDQDC... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97864-2-unknown | TDDQDC... | 2 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
P97864-24-unknown | AKPDRS... | 24 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97864-24-unknown | AKPDRS... | 24 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28372 | |||
P97864-24-unknown | AKPDRS... | 24 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
P97864-199-unknown | SGPIND... | 199 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28572 | |||
P97864-199-unknown | SGPIND... | 199 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28373 | |||
P97864-199-unknown | SGPIND... | 199 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97864-199-unknown | SGPIND... | 199 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
P97864-207-unknown | ANPRNK... | 207 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97864-207-unknown | ANPRNK... | 207 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EDGVDA | 23 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...EDGVDA | 23 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28372 | |||
...GIQADS | 198 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GIQADS | 198 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28572 | |||
...GIQADS | 198 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28373 | |||
...LYFSR | 303 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CASP1_MOUSE | 23 | GVDA.|.AKPD | inferred from experiment | unknown | MEROPS | Nunez G | Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001) | 18667412, |
CASP7_MOUSE | 198 | QADS.|.SGPI | inferred from experiment | unknown | MEROPS | Vandenabeele P | Demon D et al.:Proteome-wide substrate analysi... (C14.003) | 19759058, |
CASP1_MOUSE | 198 | QADS.|.SGPI | inferred from experiment | unknown | MEROPS | Nunez G | Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001) | 18667412, |