P63268: Actin, gamma-enteric smooth muscle

General Information

Protein names	- Actin, gamma-enteric smooth muscle - Alpha-actin-3 - Gamma-2-actin - Smooth muscle gamma-actin - Actin, gamma-enteric smooth muscle, intermediate form
Gene names	Actg2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P63268

18 N-termini

19 C-termini

24 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCEEETTALV CDNGSGLCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
        70         80         90        100        110        120
SKRGILTLKY PIEHGIITNW DDMEKIWHHS FYNELRVAPE EHPTLLTEAP LNPKANREKM
       130        140        150        160        170        180
TQIMFETFNV PAMYVAIQAV LSLYASGRTT GIVLDSGDGV THNVPIYEGY ALPHAIMRLD
       190        200        210        220        230        240
LAGRDLTDYL MKILTERGYS FVTTAEREIV RDIKEKLCYV ALDFENEMAT AASSSSLEKS
       250        260        270        280        290        300
YELPDGQVIT IGNERFRCPE TLFQPSFIGM ESAGIHETTY NSIMKCDIDI RKDLYANNVL
       310        320        330        340        350        360
SGGTTMYPGI ADRMQKEITA LAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
       370
PEYDEAGPSI VHRKCF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

18 N-termini - 19 C-termini - 24 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P63268-3-unknown	EEETTA...	3	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P63268-3-unknown	EEETTA...	3	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P63268-18-unknown	CKAGFA...	18	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33753
P63268-30-unknown	AVFPSI...	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33754
P63268-44-unknown	VMVGMG...	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33755
P63268-46-unknown	VGMGQK...	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30268
P63268-55-unknown	VGDEAQ...	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30269
P63268-106-unknown	LTEAPL...	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30270
P63268-106-unknown	LTEAPL...	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29049
P63268-106-unknown	LTEAPL...	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33756
P63268-138-unknown	QAVLSL...	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30271
P63268-141-unknown	LSLYAS...	141	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30272
P63268-191-unknown	MKILTE...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30273
P63268-229-unknown	ATAASS...	229	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29050
P63268-233-unknown	SSSSLE...	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33757
P63268-234-unknown	SSSLEK...	234	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33758
P63268-237-unknown	LEKSYE...	237	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33759
P63268-246-unknown	GQVITI...	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28488
P63268-246-unknown	GQVITI...	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32380
P63268-246-unknown	GQVITI...	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28567
P63268-246-unknown	GQVITI...	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28367
P63268-247-unknown	QVITIG...	247	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33760
P63268-299-unknown	VLSGGT...	299	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30274
P63268-299-unknown	VLSGGT...	299	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33761
P63268-301-unknown	SGGTTM...	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30275
P63268-301-unknown	SGGTTM...	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29051

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NGSGLC	17	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33753
...DDAPRA	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33754
...PRHQGV	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33755
...HQGVMV	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30268
...QKDSYV	54	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30269
...EHPTLL	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30270
...EHPTLL	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29049
...EHPTLL	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33756
...MYVAIQ	137	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30271
...AIQAVL	140	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30272
...LTDYLM	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30273
...MKILTE	195	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121577
...FENEMA	228	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29050
...MATAAS	232	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33757
...ATAASS	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33758
...ASSSSL	236	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33759
...YELPDG	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28488
...YELPDG	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32380
...YELPDG	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28567
...YELPDG	245	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28367
...ELPDGQ	246	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33760
...LYANNV	298	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30274
...LYANNV	298	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33761
...ANNVLS	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30275
...ANNVLS	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29051
...HRKCF	376	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	17	SGLC.\|.CKAG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	29	APRA.\|.AVFP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	43	HQGV.\|.VMVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	45	GVMV.\|.VGMG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @45
CATE_MOUSE	54	DSYV.\|.VGDE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @54
CATE_MOUSE	105	PTLL.\|.LTEA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @105
CATD_MOUSE	105	PTLL.\|.LTEA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
MMP2_MOUSE	105	PTLL.\|.LTEA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	137	VAIQ.\|.QAVL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @137
CATE_MOUSE	140	QAVL.\|.LSLY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @140
CATE_MOUSE	190	DYLM.\|.MKIL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @190
CATD_MOUSE	228	NEMA.\|.ATAA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
MMP2_MOUSE	232	TAAS.\|.SSSS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	233	AASS.\|.SSSL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	236	SSSL.\|.LEKS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CASP3_MOUSE	245	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
GRAB_MOUSE	245	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CASP7_MOUSE	245	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP1_MOUSE	245	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Nunez G	Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001)	18667412,
MMP2_MOUSE	246	PDGQ.\|.QVIT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	298	ANNV.\|.VLSG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @298
MMP2_MOUSE	298	ANNV.\|.VLSG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	300	NVLS.\|.SGGT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACTH_MOUSE @300
CATD_MOUSE	300	NVLS.\|.SGGT	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)