P17225: Polypyrimidine tract-binding protein 1

General Information

Protein names	- Polypyrimidine tract-binding protein 1 - PTB - Heterogeneous nuclear ribonucleoprotein I - hnRNP I
Gene names	Ptbp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P17225

12 N-termini

11 C-termini

16 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDGIVPDIAV GTKRGSDELF STCVSNGPFI MSSSASAANG NDSKKFKGDN RSAGVPSRVI
        70         80         90        100        110        120
HVRKLPSDVT EGEVISLGLP FGKVTNLLML KGKNQAFIEM NTEEAANTMV NYYTSVAPVL
       130        140        150        160        170        180
RGQPIYIQFS NHKELKTDSS PNQVRAQAAL QAVNSVQSGN LALAASAAAV DAGMAMAGQS
       190        200        210        220        230        240
PVLRIIVENL FYPVTLDVLH QIFSKFGTVL KIITFTKNNQ FQALLQYADP VSAQHAKLSL
       250        260        270        280        290        300
DGQNIYNACC TLRIDFSKLT SLNVKYNNDK SRDYTRPDLP SGDSQPSLDQ TMAAAFGLSV
       310        320        330        340        350        360
PNVHGALAPL AIPSAAAAAA ASRIAIPGLA GAGNSVLLVS NLNPERVTPQ SLFILFGVYG
       370        380        390        400        410        420
DVQRVKILFN KKENALVQMA DGSQAQLGEP PERAQAAREV SAHYTVQASE CAAAREGQED
       430        440        450        460        470        480
QGLTKDYGSS PLRFKKPGSK NFQNIFPPSA TLHLSNIPPS VSEDDLKSLF SSNGGVVKGF
       490        500        510        520
KFFQKDRKMA LIQMGSVEEA VQALIELHNH DLGENHHLRV SFSKSTI

Isoforms

Sequence View

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P17225-1-Acetylation	MDGIVP...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P17225-3-unknown	GIVPDI...	3		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28452
P17225-3-unknown	GIVPDI...	3		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28539
P17225-8-unknown	IAVGTK...	8		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32321
P17225-98-unknown	IEMNTE...	98		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29786
P17225-113-unknown	YTSVAP...	113		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33402
P17225-164-unknown	AASAAA...	164		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29787
P17225-172-unknown	AGMAMA...	172		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28453
P17225-172-unknown	AGMAMA...	172		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32322
P17225-172-unknown	AGMAMA...	172		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28540
P17225-329-unknown	LAGAGN...	329		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33403
P17225-338-unknown	LVSNLN...	338		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29788
P17225-338-unknown	LVSNLN...	338		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28801
P17225-339-unknown	VSNLNP...	339		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29789
P17225-356-unknown	FGVYGD...	356		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29790
P17225-356-unknown	FGVYGD...	356		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28802
P17225-357-unknown	GVYGDV...	357		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29791

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIVPDI	7	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32321
...KNQAFI	97	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29786
...TMVNYY	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33402
...GNLALA	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29787
...AAAVDA	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28453
...AAAVDA	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32322
...AAAVDA	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28540
...IAIPGL	328	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33403
...GNSVLL	337	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29788
...GNSVLL	337	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28801
...NSVLLV	338	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29789
...SLFILF	355	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29790
...SLFILF	355	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28802
...LFILFG	356	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29791
...SKSTI	527	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_MOUSE	2	.\|.GIVP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP7_MOUSE	2	.\|.GIVP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
GRAB_MOUSE	7	VPDI.\|.IAVG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATE_MOUSE	97	QAFI.\|.IEMN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @97
MMP2_MOUSE	112	VNYY.\|.YTSV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	163	LALA.\|.AASA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @163
CASP3_MOUSE	171	AVDA.\|.AGMA	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
GRAB_MOUSE	171	AVDA.\|.AGMA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CASP7_MOUSE	171	AVDA.\|.AGMA	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
MMP2_MOUSE	328	IPGL.\|.LAGA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	337	SVLL.\|.LVSN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @337
CATD_MOUSE	337	SVLL.\|.LVSN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PTBP1_MOUSE @337
CATE_MOUSE	338	VLLV.\|.VSNL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @338
CATE_MOUSE	355	FILF.\|.FGVY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @355
CATD_MOUSE	355	FILF.\|.FGVY	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PTBP1_MOUSE @355
CATE_MOUSE	356	ILFG.\|.GVYG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PTBP1_MOUSE @356

TopFIND

P17225: Polypyrimidine tract-binding protein 1

General Information

12

N-termini

11

C-termini

16

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

12 N-termini - 11 C-termini - 16 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates