P56399: Ubiquitin carboxyl-terminal hydrolase 5
Protein names | - Ubiquitin carboxyl-terminal hydrolase 5 - 3.4.19.12 - Deubiquitinating enzyme 5 - Isopeptidase T - Ubiquitin thioesterase 5 - Ubiquitin-specific-processing protease 5 |
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Gene names | Usp5 |
Organism | Mus musculus |
Protease Family | |
Protease ID | C19.001 |
Chromosome location | |
UniProt ID | P56399 |
14
N-termini
8
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAELSEEALL SVLPTIRVPK AGDRVHKDEC AFSFDTPESE GGLYICMNTF LGFGKQYVER
70 80 90 100 110 120
HFNKTGQRVY LHLRRTRRPK EEDTSAGTGD PPRKKPTRLA IGVEGGFDLT EDKFEFDEDV
130 140 150 160 170 180
KIVILPDYLE IARDGLGGLP DIVRDRVTSA VEALLSADSA SRKQEVQAWD GEVRQVSKHA
190 200 210 220 230 240
FNLKQLDNPA RIPPCGWKCS KCDMRENLWL NLTDGSILCG RRYFDGSGGN NHAVEHYRET
250 260 270 280 290 300
GYPLAVKLGT ITPDGADVYS YDEDDMVLDP SLAEHLSHFG IDMLKMQKTD KTMTELEIDM
310 320 330 340 350 360
NQRIGEWELI QESGVPLKPL FGPGYTGIRN LGNSCYLNSV VQVLFSIPDF QRKYVDKLEK
370 380 390 400 410 420
IFQNAPTDPT QDFSTQVAKL GHGLLSGEYS KPALESGDGE QVPEQKEVQD GIAPRMFKAL
430 440 450 460 470 480
IGKGHPEFST NRQQDAQEFF LHLINMVERN CRSSENPNEV FRFLVEEKIK CLATEKVKYT
490 500 510 520 530 540
QRVDYIMQLP VPMDAALNKE ELLEYEEKKR QAEEEKVPLP ELVRAQVPFS SCLEAYGAPE
550 560 570 580 590 600
QVDDFWSTAL QAKSVAVKTT RFASFPDYLV IQIKKFTFGL DWVPKKLDVS IEMPEELDIS
610 620 630 640 650 660
QLRGTGLQPG EEELPDIAPP LVTPDEPKGS LGFYGNEDED SFCSPHFSSP TSPMLDESVI
670 680 690 700 710 720
IQLVEMGFPM DACRKAVYYT GNSGAEAAMN WVMSHMDDPD FANPLILPGS SGPGSTSAAA
730 740 750 760 770 780
DPPPEDCVTT IVSMGFSRDQ ALKALRATNN SLERAVDWIF SHIDDLDAEA AMDISEGRSA
790 800 810 820 830 840
AESISESVPV GPKVRDGPGK YQLFAFISHM GTSTMCGHYV CHIKKEGRWV IYNDQKVCAS
850
EKPPKDLGYI YFYQRVVS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
14 N-termini - 8 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P56399-2-unknown | MAELSE... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
P56399-2-unknown | MAELSE... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P56399-2-Acetylation | AELSEE... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P56399-2-Acetylation | AELSEE... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
P56399-47-unknown | MNTFLG... | 47 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000118200 | |||
P56399-127-unknown | DYLEIA... | 127 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
P56399-152-unknown | EALLSA... | 152 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
P56399-154-unknown | LLSADS... | 154 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33628 | |||
P56399-212-unknown | LTDGSI... | 212 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33629 | |||
P56399-227-unknown | SGGNNH... | 227 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
P56399-321-unmodified | FGPGYT... | 321 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
P56399-417-unknown | FKALIG... | 417 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33630 | |||
P56399-420-unknown | LIGKGH... | 420 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33631 | |||
P56399-768-unmodified | AEAAMD... | 768 | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | |||
P56399-768-unmodified | AEAAMD... | 768 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
P56399-768-unknown | AEAAMD... | 768 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28476 | |||
P56399-768-unknown | AEAAMD... | 768 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28554 | |||
P56399-783-unmodified | SISESV... | 783 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SAVEAL | 153 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33628 | |||
...NLWLNL | 211 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33629 | |||
...ITPDGA | 255 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000118200 | |||
...LKPLFG | 321 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000117439 | |||
...IAPRMF | 416 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33630 | |||
...RMFKAL | 419 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33631 | |||
...IDDLDA | 767 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28476 | |||
...IDDLDA | 767 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28554 | |||
...QRVVS | 858 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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