Q922B2: Aspartate--tRNA ligase, cytoplasmic

General Information

Protein names	- Aspartate--tRNA ligase, cytoplasmic - 6.1.1.12 {ECO:0000250\|UniProtKB:P15178} - Aspartyl-tRNA synthetase - AspRS
Gene names	Dars
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q922B2

4 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPSTNASRKG QEKPREIVDA AEDYAKERYG ISSMIQSQEK PDRVLVRVKD LTVQKADDVV
        70         80         90        100        110        120
WVRARVHTSR AKGKQCFLVL RQQQFNVQAL VAVGDHASKQ MVKFAANINK ESIIDVEGVV
       130        140        150        160        170        180
RKVNQKIGSC TQQDVELHVQ KIYVISLAEP RLPLQLDDAI RPEVEGEEDG RATVNQDTRL
       190        200        210        220        230        240
DNRVIDLRTS TSQAIFRLQS GICHLFRETL INKGFVEIQT PKIISAASEG GANVFTVSYF
       250        260        270        280        290        300
KNNAYLAQSP QLYKQMCICA DFEKVFCIGP VFRAEDSNTH RHLTEFVGLD IEMAFNYHYH
       310        320        330        340        350        360
EVVEEIADTL VQIFKGLQER FQTEIQTVSK QFPCEPFKFL EPTLRLEYCE ALAMLREAGV
       370        380        390        400        410        420
EMDDEEDLST PNEKLLGRLV KEKYDTDFYV LDKYPLAVRP FYTMPDPRNP KQSNSYDMFM
       430        440        450        460        470        480
RGEEILSGAQ RIHDPQLLTE RALHHGIDLE KIKAYIDSFR FGAPPHAGGG IGLERVTMLF
       490        500
LGLHNVRQTS MFPRDPKRLT P

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q922B2-1-unknown	MPSTNA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q922B2-20-unknown	AAEDYA...	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28520
Q922B2-20-unknown	AAEDYA...	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28599
Q922B2-20-unknown	AAEDYA...	20		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q922B2-34-unknown	MIQSQE...	34	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30919
Q922B2-35-unknown	IQSQEK...	35	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30920

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...REIVDA	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28520
...REIVDA	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28599
...YGISSM	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30919
...GISSMI	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30920
...KRLTP	501	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_MOUSE	19	IVDA.\|.AAED	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP7_MOUSE	19	IVDA.\|.AAED	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CATE_MOUSE	33	ISSM.\|.MIQS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SYDC_MOUSE @33
CATE_MOUSE	34	SSMI.\|.IQSQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SYDC_MOUSE @34

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)