TopFIND 4.0

P10749: Interleukin-1 beta

General Information

Protein names
- Interleukin-1 beta
- IL-1 beta
Gene names Il1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P10749

1

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATVPELNCE MPPFDSDEND LFFEVDGPQK MKGCFQTFDL GCPDESIQLQ ISQQHINKSF 
        70         80         90        100        110        120 
RQAVSLIVAV EKLWQLPVSF PWTFQDEDMS TFFSFIFEEE PILCDSWDDD DNLLVCDVPI 
       130        140        150        160        170        180 
RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK 
       190        200        210        220        230        240 
GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS 
       250        260    
TSQAEHKPVF LGNNSGQDII DFTMESVSS

Isoforms



Sequence View



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P10749-118-unknown VPIRQL... 118 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P10749-118-unknown VPIRQL... 118 inferred from cleavage unknown TopFIND Inferred from cleavage TC28381

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)