P51859: Hepatoma-derived growth factor

General Information

Protein names	- Hepatoma-derived growth factor - HDGF
Gene names	Hdgf
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P51859

6 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP
        70         80         90        100        110        120
KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY QSSQKKSCAA EPEVEPEAHE
       130        140        150        160        170        180
GDGDKKGSAE GSSDEEGKLV IDEPAKEKNE KGTLKRRAGD VLEDSPKRPK ESGDHEEEDK
       190        200        210        220        230
EIAALEGERP LPVEVEKNST PSEPDSGQGP PAEEEEGEEE AAKEEAEAQG VRDHESL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P51859-1-unknown	MSRSNR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P51859-5-unknown	NRQKEY...	5	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P51859-13-unknown	GDLVFA...	13	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P51859-33-unknown	MPEAAV...	33	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000124803
P51859-206-unknown	SGQGPP...	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28471
P51859-209-unknown	GPPAEE...	209	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28358

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PSEPDS	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28471
...PDSGQG	208	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28358
...GVRDHE	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000124803
...DHESL	237	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_MOUSE	205	EPDS.\|.SGQG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
CASP1_MOUSE	208	SGQG.\|.GPPA	inferred from experiment	unknown	MEROPS	Nunez G	Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001)	18667412,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)