Q8K3X4: Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7}
Protein names | - Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7} - 2.3.2.27 {ECO:0000250|UniProtKB:Q9H1B7} - Enhanced at puberty protein 1 - Interferon regulatory factor 2-binding protein-like |
---|---|
Gene names | Irf2bpl |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8K3X4 |
4
N-termini
4
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF SEPVCRGCVN YEGADRIEFV IETARQLKRA
70 80 90 100 110 120
HGCFQDGRSP GPPPPVGVKT VALSAKEAAA AAAAAQQQQQ QQQQQQQQLN HVDGSTKPAV
130 140 150 160 170 180
LAAPSGLERY GLSAAAAAAA AAAAVEQRSR FEYPPPPVSL GSSSHAARLP NGLGGPNGFP
190 200 210 220 230 240
KPAPEEGPPE LNRQSPNSSS AATSVASRRG THSGLVTGLP NPGGGGGPQL TVPPNLLPQT
250 260 270 280 290 300
LLNGPASAAV LPPPHGLGGS RGPPTPAPPG APGGPACLGG PPGVSATVSS APSSTSSTVA
310 320 330 340 350 360
EVGVGAAGKR PGSVSSTDQE RELKEKQRNA EALAELSESL RNRAEEWANK PKMVRDTLLT
370 380 390 400 410 420
LAGCTPYEVR FKKDHSLLGR VFAFDAVSKP GMDYELKLFI EYPTGSGNVY SSASGVAKQM
430 440 450 460 470 480
YQDCMKDFGR GLSSGFKYLE YEKKHGSGDW RLLGDLLPEA VRFFKEGVPG ADMLPQPYLD
490 500 510 520 530 540
ASCPMLPTAL VSLSRAPSAP PGTGALPPAA PTGRGAASSL RKRKASPEPP DSAESALKLG
550 560 570 580 590 600
EEQQRQQWMA NQSEALKLTM SAGGFAAPGH SAGGPPPPPP PLGPHSNRTT PPESAPQNGP
610 620 630 640 650 660
SPMAALMSVA DTLGTAHSPK DGSSVHSTTA SARRNSSSPV SPASVPGQRR LASRNGDLNL
670 680 690 700 710 720
QVAPPPPSAH PGMDQVHPQN IPDSPMANSG PLCCTICHER LEDTHFVQCP SVPSHKFCFP
730 740 750 760 770
CSRESIKAQG ATGEVYCPSG EKCPLVGSNV PWAFMQGEIA TILAGDVKVK KERDP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8K3X4-1-unknown | MSAAQV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8K3X4-116-unknown | TKPAVL... | 116 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28408 | |||
Q8K3X4-762-unknown | ILAGDV... | 762 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29261 | |||
Q8K3X4-762-unknown | ILAGDV... | 762 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30831 | |||
Q8K3X4-764-unknown | AGDVKV... | 764 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29262 | |||
Q8K3X4-764-unknown | AGDVKV... | 764 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30832 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...HVDGST | 115 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28408 | |||
...GEIATI | 761 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29261 | |||
...GEIATI | 761 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30831 | |||
...IATILA | 763 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29262 | |||
...IATILA | 763 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30832 | |||
...KERDP | 775 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CASP1_MOUSE | 115 | DGST.|.TKPA | inferred from experiment | unknown | MEROPS | Nunez G | Lamkanfi M et al.:Targeted peptidecentric proteom... (C14.001) | 18667412, |
CATD_MOUSE | 761 | IATI.|.ILAG | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> I2BPL_MOUSE @761 | ||
CATE_MOUSE | 761 | IATI.|.ILAG | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> I2BPL_MOUSE @761 | ||
CATD_MOUSE | 763 | TILA.|.AGDV | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> I2BPL_MOUSE @763 | ||
CATE_MOUSE | 763 | TILA.|.AGDV | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> I2BPL_MOUSE @763 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|