Q5RJH6: Protein SMG7

General Information

Protein names	- Protein SMG7 - EST1-like protein C - SMG-7 homolog
Gene names	Smg7
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5RJH6

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLQSAQYLR QAEVLKAEMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY ALDKKVEQDL
        70         80         90        100        110        120
WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG FYTQLLQELC TVFNVDLPCR
       130        140        150        160        170        180
VKSSQLGIIS NKQTHSSTIV KPQSSSCSYI CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ
       190        200        210        220        230        240
LVPSNGQPYN QLAILASSKG DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEL
       250        260        270        280        290        300
KTKWGVSDFI KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI
       310        320        330        340        350        360
NLFQLHHLRD FSNETEQHSY SQDEQLCWTQ LLALFMSFLG ILCKCPLQND SQESNNAYPL
       370        380        390        400        410        420
PAVKVSMDWL RLRPRVFQEA VVDERQYIWP WLISLLNSFH PREDDLSNTN ATPLPEEFEL
       430        440        450        460        470        480
QGFLALRPSF RNLDFSKGHQ GITGDKEGQQ RRIRQQRLIS IGKWIADNQP RLIQCENEVG
       490        500        510        520        530        540
KLLFITEIPE LILEDPSEAK ENLILQETSV VESLATDGSP GLKSVLSTGR NPSNSCDSGE
       550        560        570        580        590        600
KPVVTFKENI KPREVNQGRS FPPKEVKSQT ELRKTPVSEA RKTPVTQTPS QTSNSQFIPI
       610        620        630        640        650        660
HHPGAFPPLP SRPGFPPPTY VIPPPVAFSM GSGYTFPAGV SVPGTFLQST AHSPAGNQVQ
       670        680        690        700        710        720
AGKQSHIPYS QQRPSGPGPM NQGPQQSQPP SQPPLTSLPA QPTAQSTSQL QVQALAQQQQ
       730        740        750        760        770        780
SPTKVIPALG KSPPHHSGFQ QYQQADASKQ LWNPPQVQSP LGKIMPVKQS YYLQTQDPIK
       790        800        810        820        830        840
LFEPSLQPPV IQQQPLEKKM KPFPMEPYNH NPSEVKVPEF YWDSSYSMAD NRAVMAQQPN
       850        860        870        880        890        900
MDRRSKRSPG VFRPEQDPVP RMPFEDPKSS PLLPPDLLKS LAALEEEEEL IFSNPPDLYP
       910        920        930        940        950        960
ALLGPLASLP GRSLFKSLLE KPSELMSHSS SFLSLTGFSV NQERYPNSSM FNEVYGKNLT
       970        980        990       1000       1010       1020
TSSKAELNPS VASQETSLYS LFEGTPWSPS LPASSDHSTP ASQSPHSSNP SSLPSSPPTH
      1030       1040       1050       1060       1070       1080
NHNSAPFSNF GPIGTPDNRD RRPADRWKTD KPAMGGFGVD YLSATSSSES SWHQASTPSG
      1090       1100       1110       1120       1130
TWTGHGPSME DSSAVLMESL KSIWSSSMMH PGPSALEQLL MQQKQKQQRG QGAMNPPH

Isoforms

- Isoform 2 of Protein SMG7 - Isoform 3 of Protein SMG7 - Isoform 2 of Protein SMG7

Sequence View

        10         20         30         40         50         60
MSLQSAQYLR QAEVLKAEMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY ALDKKVEQDL
        70         80         90        100        110        120
WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG FYTQLLQELC TVFNVDLPCR
       130        140        150        160        170        180
VKSSQLGIIS NKQTHSSTIV KPQSSSCSYI CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ
       190        200        210        220        230        240
LVPSNGQPYN QLAILASSKG DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEL
       250        260        270        280        290        300
KTKWGVSDFI KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI
       310        320        330        340        350        360
NLFQLHHLRD FSNETEQHSY SQDEQLCWTQ LLALFMSFLG ILCKCPLQND SQESNNAYPL
       370        380        390        400        410        420
PAVKVSMDWL RLRPRVFQEA VVDERQYIWP WLISLLNSFH PREDDLSNTN ATPLPEEFEL
       430        440        450        460        470        480
QGFLALRPSF RNLDFSKGHQ GITGDKEGQQ RRIRQQRLIS IGKWIADNQP RLIQCENEVG
       490        500        510        520        530        540
KLLFITEIPE LILEDPSEAK ENLILQETSV VESLATDGSP GLKSVLSTGR NPSNSCDSGE
       550        560        570        580        590        600
KPVVTFKENI KPREVNQGRS FPPKEVKSQT ELRKTPVSEA RKTPVTQTPS QTSNSQFIPI
       610        620        630        640        650        660
HHPGAFPPLP SRPGFPPPTY VIPPPVAFSM GSGYTFPAGV SVPGTFLQST AHSPAGNQVQ
       670        680        690        700        710        720
AGKQSHIPYS QQRPSGPGPM NQGPQQSQPP SQPPLTSLPA QPTAQSTSQL QVQALAQQQQ
       730        740        750        760        770        780
SPTKVIPALG KSPPHHSGFQ QYQQADASKQ LWNPPQVQSP LGKIMPVKQS YYLQTQDPIK
       790        800        810        820        830        840
LFEPSLQPPV IQQQPLEKKM KPFPMEPYNH NPSEVKVPEF YWDSSYSMAD NRAVMAQQPN
       850        860        870        880        890        900
MDRRSKRSPG VFRPEQDPVP RMPFEDPKSS PLLPPDLLKS LAALEEEEEL IFSNPPDLYP
       910        920        930        940        950        960
ALLGPLASLP GRSLFKSLLE KPSELMSHSS SFLSLTGFSV NQERYPNSSM FNEVYGKNLT
       970        980        990       1000       1010       1020
TSSKAELNPS VASQETSLYS LFEGTPWSPS LPASSDHSTP ASQSPHSSNP SSLPSSPPTH
      1030       1040       1050       1060       1070       1080
NHNSAPFSNF GPIGTPDNRD RRPADRWKTD KPAMGGFGVD YLSATSSSES SWHQASTPSG
      1090       1100       1110       1120       1130
TWTGHGPSME DSSAVLMESL KSIWSSSMMH PGPSALEQLL MQQKQKQQRG QGAMNPPH         10         20         30         40         50         60
MSLQSAQYLR QAEVLKAEMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY ALDKKVEQDL
        70         80         90        100        110        120
WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG FYTQLLQELC TVFNVDLPCR
       130        140        150        160        170        180
VKSSQLGIIS NKQTHSSTIV KPQSSSCSYI CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ
       190        200        210        220        230        240
LVPSNGQPYN QLAILASSKG DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEL
       250        260        270        280        290        300
KTKWGVSDFI KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI
       310        320        330        340        350        360
NLFQLHHLRD FSNETEQHSY SQDEQLCWTQ LLALFMSFLG ILCKCPLQND SQESNNAYPL
       370        380        390        400        410        420
PAVKVSMDWL RLRPRVFQEA VVDERQYIWP WLISLLNSFH PREDDLSNTN ATPLPEEFEL
       430        440        450        460        470        480
QGFLALRPSF RNLDFSKGHQ GITGDKEGQQ RRIRQQRLIS IGKWIADNQP RLIQCENEVG
       490        500        510        520        530        540
KLLFITEIPE LILEDPSEAK ENLILQETSV VESLATDGSP GLKSVLSTGR NPSNSCDSGE
       550        560        570        580        590        600
KPVVTFKENI KPREVNQGRS FPPKEVKSQT ELRKTPVSEA RKTPVTQTPS QTSNSQFIPI
       610        620        630        640        650        660
HHPGAFPPLP SRPGFPPPTY VIPPPVAFSM GSGYTFPAGV SVPGTFLQST AHSPAGNQVQ
       670        680        690        700        710        720
AGKQSHIPYS QQRPSGPGPM NQGPQQSQPP SQPPLTSLPA QPTAQSTSQL QVQALAQQQQ
       730        740        750        760        770        780
SPTKVIPALG KSPPHHSGFQ QYQQADASKQ LWNPPQVQSP LGKIMPVKQS YYLQTQDPIK
       790        800        810        820        830        840
LFEPSLQPPV IQQQPLEKKM KPFPMEPYNH NPSEVKVPEF YWDSSYSMAD NRAVMAQQPN
       850        860        870        880        890        900
MDRRSKRSPG VFRPEQDPVP RMPFEDPKSS PLLPPDLLKS LAALEEEEEL IFSNPPDLYP
       910        920        930        940        950        960
ALLGPLASLP GRSLFKSLLE KPSELMSHSS SFLSLTGFSV NQERYPNSSM FNEVYGKNLT
       970        980        990       1000       1010       1020
TSSKAELNPS VASQETSLYS LFEGTPWSPS LPASSDHSTP ASQSPHSSNP SSLPSSPPTH
      1030       1040       1050       1060       1070       1080
NHNSAPFSNF GPIGTPDNRD RRPADRWKTD KPAMGGFGVD YLSATSSSES SWHQASTPSG
      1090       1100       1110       1120       1130
TWTGHGPSME DSSAVLMESL KSIWSSSMMH PGPSALEQLL MQQKQKQQRG QGAMNPPH         10         20         30         40         50         60
MSLQSAQYLR QAEVLKAEMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY ALDKKVEQDL
        70         80         90        100        110        120
WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG FYTQLLQELC TVFNVDLPCR
       130        140        150        160        170        180
VKSSQLGIIS NKQTHSSTIV KPQSSSCSYI CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ
       190        200        210        220        230        240
LVPSNGQPYN QLAILASSKG DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEL
       250        260        270        280        290        300
KTKWGVSDFI KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI
       310        320        330        340        350        360
NLFQLHHLRD FSNETEQHSY SQDEQLCWTQ LLALFMSFLG ILCKCPLQND SQESNNAYPL
       370        380        390        400        410        420
PAVKVSMDWL RLRPRVFQEA VVDERQYIWP WLISLLNSFH PREDDLSNTN ATPLPEEFEL
       430        440        450        460        470        480
QGFLALRPSF RNLDFSKGHQ GITGDKEGQQ RRIRQQRLIS IGKWIADNQP RLIQCENEVG
       490        500        510        520        530        540
KLLFITEIPE LILEDPSEAK ENLILQETSV VESLATDGSP GLKSVLSTGR NPSNSCDSGE
       550        560        570        580        590        600
KPVVTFKENI KPREVNQGRS FPPKEVKSQT ELRKTPVSEA RKTPVTQTPS QTSNSQFIPI
       610        620        630        640        650        660
HHPGAFPPLP SRPGFPPPTY VIPPPVAFSM GSGYTFPAGV SVPGTFLQST AHSPAGNQVQ
       670        680        690        700        710        720
AGKQSHIPYS QQRPSGPGPM NQGPQQSQPP SQPPLTSLPA QPTAQSTSQL QVQALAQQQQ
       730        740        750        760        770        780
SPTKVIPALG KSPPHHSGFQ QYQQADASKQ LWNPPQVQSP LGKIMPVKQS YYLQTQDPIK
       790        800        810        820        830        840
LFEPSLQPPV IQQQPLEKKM KPFPMEPYNH NPSEVKVPEF YWDSSYSMAD NRAVMAQQPN
       850        860        870        880        890        900
MDRRSKRSPG VFRPEQDPVP RMPFEDPKSS PLLPPDLLKS LAALEEEEEL IFSNPPDLYP
       910        920        930        940        950        960
ALLGPLASLP GRSLFKSLLE KPSELMSHSS SFLSLTGFSV NQERYPNSSM FNEVYGKNLT
       970        980        990       1000       1010       1020
TSSKAELNPS VASQETSLYS LFEGTPWSPS LPASSDHSTP ASQSPHSSNP SSLPSSPPTH
      1030       1040       1050       1060       1070       1080
NHNSAPFSNF GPIGTPDNRD RRPADRWKTD KPAMGGFGVD YLSATSSSES SWHQASTPSG
      1090       1100       1110       1120       1130
TWTGHGPSME DSSAVLMESL KSIWSSSMMH PGPSALEQLL MQQKQKQQRG QGAMNPPH

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q5RJH6-1-unknown	MSLQSA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt90038
Q5RJH6-2-unknown	MSLQSA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q5RJH6-2-unknown	MSLQSA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5RJH6-2-Acetylation	SLQSAQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5RJH6-2-Acetylation	SLQSAQ...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111261
Q5RJH6-2-Acetylation	SLQSAQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q5RJH6-518-unknown	GSPGLK...	518		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28382
Q5RJH6-518-unknown	GSPGLK...	518		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt153613
Q5RJH6-518-unknown	GSPGLK...	518		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt153720

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SLATDG	517	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28382
...SLATDG	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137036
...SLATDG	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137143
...MNPPH	1138	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...MNPPH	1138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85656
...MNPPH	1138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85655

TopFIND

Q5RJH6: Protein SMG7

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates