Q9WUA3: ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255|HAMAP-Rule:MF_03184}

General Information

Protein names	- ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255\|HAMAP-Rule:MF_03184} - ATP-PFK {ECO:0000255\|HAMAP-Rule:MF_03184} - PFK-P - 2.7.1.11 {ECO:0000255\|HAMAP-Rule:MF_03184} - 6-phosphofructokinase type C - Phosphofructo-1-kinase isozyme C - PFK-C - Phosphohexokinase {ECO:0000255\|HAMAP-Rule:MF_03184}
Gene names	Pfkp
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9WUA3

6 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of 6-phosphofructokinase type C - Isoform 2 of ATP-dependent 6-phosphofructokinase, platelet type

Sequence View

        10         20         30         40         50         60
MSDLDSSSSS AYPKYLEHLS GDGKAIGVLT SGGDAQGMNA AVRAVVRMGI YTGAKVYFIY
        70         80         90        100        110        120
EGYQGLVDGG SNIVEAKWDC VSSILQVGGT IIGSARCKAF RSREGRLKAA CNLARLGITN
       130        140        150        160        170        180
LCVIGGDGSL TGANLFRKEW SGLLEELARN GDIDNDTVQK YSYLNVVGMV GSIDNDFCGT
       190        200        210        220        230        240
DMTIGTDSAL HRIIEVVDAI MTTAQSHQRT FVLEVMGRHC GYLALVSALT CGADWVFLPE
       250        260        270        280        290        300
SPPEEDWEEN MCLKLSENRA RKKRLNIIIV SEGAIDMQNK PITSEKIKEL VVKNLGFDTR
       310        320        330        340        350        360
VTILGHVQRG GTPSAFDRIL ASRMGVEAVI ALLEATPETP ACVVSLRGNQ AVRLPLMECV
       370        380        390        400        410        420
QMTQDVQKAM DERRFKEAVK LRGRRFEGNL NTYKRLAIKL PDEKIVKSNC NVAVINVGAP
       430        440        450        460        470        480
AAGMNAAVRS AVRVGIADGH KMFAIYDGFE GFANGQIKEI GWADVGGWTG QGGSILGTKR
       490        500        510        520        530        540
TLPGKYLEKI AEQMHSHSIN ALLIIGGFEA YLGLLELAAA REKHEAFCVP MVMVPATVSN
       550        560        570        580        590        600
NVPGSDFSIG ADTALNTITD TCDRIKQSAS GTKRRVFIIE TMGGYCGYLA NMGALAAGAD
       610        620        630        640        650        660
AAYIFEEPFD IGDLQSNVVH LTEKMKTSIQ RGLVLRNESC SVNYTTDFIY QLYSEEGKGV
       670        680        690        700        710        720
FDCRKNVLGH MQQGGAPSPF DRNFGTKISA KAMEWISAKL KGSQGTGKKF VSDDSICVLG
       730        740        750        760        770        780
ICKRDLLFQP VAELKKVTDF EHRIPKEQWW LKLRPIMKIL AKYEASYDMS DSGKLESLQH

HEEL         10         20         30         40         50         60
MSDLDSSSSS AYPKYLEHLS GDGKAIGVLT SGGDAQGMNA AVRAVVRMGI YTGAKVYFIY
        70         80         90        100        110        120
EGYQGLVDGG SNIVEAKWDC VSSILQVGGT IIGSARCKAF RSREGRLKAA CNLARLGITN
       130        140        150        160        170        180
LCVIGGDGSL TGANLFRKEW SGLLEELARN GDIDNDTVQK YSYLNVVGMV GSIDNDFCGT
       190        200        210        220        230        240
DMTIGTDSAL HRIIEVVDAI MTTAQSHQRT FVLEVMGRHC GYLALVSALT CGADWVFLPE
       250        260        270        280        290        300
SPPEEDWEEN MCLKLSENRA RKKRLNIIIV SEGAIDMQNK PITSEKIKEL VVKNLGFDTR
       310        320        330        340        350        360
VTILGHVQRG GTPSAFDRIL ASRMGVEAVI ALLEATPETP ACVVSLRGNQ AVRLPLMECV
       370        380        390        400        410        420
QMTQDVQKAM DERRFKEAVK LRGRRFEGNL NTYKRLAIKL PDEKIVKSNC NVAVINVGAP
       430        440        450        460        470        480
AAGMNAAVRS AVRVGIADGH KMFAIYDGFE GFANGQIKEI GWADVGGWTG QGGSILGTKR
       490        500        510        520        530        540
TLPGKYLEKI AEQMHSHSIN ALLIIGGFEA YLGLLELAAA REKHEAFCVP MVMVPATVSN
       550        560        570        580        590        600
NVPGSDFSIG ADTALNTITD TCDRIKQSAS GTKRRVFIIE TMGGYCGYLA NMGALAAGAD
       610        620        630        640        650        660
AAYIFEEPFD IGDLQSNVVH LTEKMKTSIQ RGLVLRNESC SVNYTTDFIY QLYSEEGKGV
       670        680        690        700        710        720
FDCRKNVLGH MQQGGAPSPF DRNFGTKISA KAMEWISAKL KGSQGTGKKF VSDDSICVLG
       730        740        750        760        770        780
ICKRDLLFQP VAELKKVTDF EHRIPKEQWW LKLRPIMKIL AKYEASYDMS DSGKLESLQH

HEEL

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9WUA3-1-unknown	MSDLDS...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78492
Q9WUA3-1-Acetylation	MSDLDS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9WUA3-1-Acetylation	MSDLDS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106127
Q9WUA3-359-unknown	CVQMTQ...	359		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31337
Q9WUA3-359-unknown	CVQMTQ...	359		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151139
Q9WUA3-360-unknown	VQMTQD...	360		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31339
Q9WUA3-360-unknown	VQMTQD...	360		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151170
Q9WUA3-362-unknown	MTQDVQ...	362		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31341
Q9WUA3-362-unknown	MTQDVQ...	362		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151239
Q9WUA3-553-unknown	TALNTI...	553		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32592

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPLMEC	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31337
...LPLMEC	358	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134541
...PLMECV	359	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31339
...PLMECV	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134572
...MECVQM	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31341
...MECVQM	361	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134641
...SIGADT	552	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32592
...HHEEL	784	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	358	LMEC.\|.CVQM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> K6PP_MOUSE @358
CATE_MOUSE	359	MECV.\|.VQMT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> K6PP_MOUSE @359
CATE_MOUSE	361	CVQM.\|.MTQD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> K6PP_MOUSE @361
GRAB_MOUSE	552	GADT.\|.TALN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)