P99024: Tubulin beta-5 chain

General Information

Protein names	- Tubulin beta-5 chain
Gene names	Tubb5
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P99024

18 N-termini

13 C-termini

11 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MREIVHIQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLDRISVY YNEATGGKYV
        70         80         90        100        110        120
PRAILVDLEP GTMDSVRSGP FGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDSVLDVV
       130        140        150        160        170        180
RKEAESCDCL QGFQLTHSLG GGTGSGMGTL LISKIREEYP DRIMNTFSVV PSPKVSDTVV
       190        200        210        220        230        240
EPYNATLSVH QLVENTDETY CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL
       250        260        270        280        290        300
RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVPELT QQVFDAKNMM
       310        320        330        340        350        360
AACDPRHGRY LTVAAVFRGR MSMKEVDEQM LNVQNKNSSY FVEWIPNNVK TAVCDIPPRG
       370        380        390        400        410        420
LKMAVTFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS
       430        440
EYQQYQDATA EEEEDFGEEA EEEA

Isoforms

Sequence View

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Directness:

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Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

18 N-termini - 13 C-termini - 11 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P99024-1-unknown	MREIVH...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P99024-34-unmodified	GTYHGD...	34		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P99024-35-unknown	TYHGDS...	35	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33832
P99024-48-unknown	SVYYNE...	48		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P99024-64-unknown	ILVDLE...	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33833
P99024-73-unknown	MDSVRS...	73	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000134598
P99024-77-unknown	RSGPFG...	77	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P99024-112-unknown	LVDSVL...	112	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33834
P99024-113-unknown	VDSVLD...	113	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30376
P99024-206-unknown	ALYDIC...	206	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32404
P99024-228-unknown	LVSATM...	228	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33835
P99024-232-unknown	TMSGVT...	232	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33836
P99024-293-unmodified	VFDAKN...	293		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P99024-295-unknown	DAKNMM...	295	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30377
P99024-366-unknown	TFIGNS...	366	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30378
P99024-367-unknown	FIGNST...	367	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33837
P99024-369-unknown	GNSTAI...	369		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P99024-371-unknown	STAIQE...	371	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33838

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IDPTGT	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33832
...YVPRAI	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33833
...TEGAEL	111	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33834
...EGAELV	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30376
...QLTHSL	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134598
...CIDNEA	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32404
...GDLNHL	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33835
...HLVSAT	231	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33836
...TQQVFD	294	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30377
...LKMAVT	365	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30378
...KMAVTF	366	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33837
...TFIGNS	370	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33838
...AEEEA	444	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	34	PTGT.\|.TYHG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	63	PRAI.\|.ILVD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	111	GAEL.\|.LVDS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	112	AELV.\|.VDSV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBB5_MOUSE @112
GRAB_MOUSE	205	DNEA.\|.ALYD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MMP2_MOUSE	227	LNHL.\|.LVSA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	231	VSAT.\|.TMSG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	294	QVFD.\|.DAKN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBB5_MOUSE @294
CATE_MOUSE	365	MAVT.\|.TFIG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBB5_MOUSE @365
MMP2_MOUSE	366	AVTF.\|.FIGN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	370	IGNS.\|.STAI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)