Q9Z2X1: Heterogeneous nuclear ribonucleoprotein F

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein F - hnRNP F - Heterogeneous nuclear ribonucleoprotein F, N-terminally processed
Gene names	Hnrnpf
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z2X1

8 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMLGPEGGEG YVVKLRGLPW SCSIEDVQNF LSDCTIHDGV AGVHFIYTRE GRQSGEAFVE
        70         80         90        100        110        120
LESEDDVKLA LKKDRESMGH RYIEVFKSHR TEMDWVLKHS GPNSADSAND GFVRLRGLPF
       130        140        150        160        170        180
GCTKEEIVQF FSGLEIVPNG ITLPVDPEGK ITGEAFVQFA SQELAEKALG KHKERIGHRY
       190        200        210        220        230        240
IEVFKSSQEE VRSYSDPPLK FMSVQRPGPY DRPGTARRYI GIVKQAGLDR MRSGAYSAGY
       250        260        270        280        290        300
GGYEEYSGLS DGYGFTTDLF GRDLSYCLSG MYDHRYGDSE FTVQSTTGHC VHMRGLPYKA
       310        320        330        340        350        360
TENDIYNFFS PLNPVRVHIE IGPDGRVTGE ADVEFATHEE AVAAMSKDRA NMQHRYIELF
       370        380        390        400        410
LNSTTGASNG AYSSQVMQGM GVSAAQATYS GLESQSVSGC YGAGYSGQNS MGGYD

Isoforms

- Isoform 2 of Heterogeneous nuclear ribonucleoprotein F

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Z2X1-1-Acetylation	MMLGPE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z2X1-1-Acetylation	MMLGPE...	1	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9Z2X1-2-Acetylation	MLGPEG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z2X1-2-Acetylation	MLGPEG...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Z2X1-2-Acetylation	MLGPEG...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q9Z2X1-2-Acetylation	MLGPEG...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9Z2X1-2-Acetylation	MLGPEG...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q9Z2X1-116-unknown	RGLPFG...	116		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9Z2X1-116-unknown	RGLPFG...	116		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197171
Q9Z2X1-222-unknown	IVKQAG...	222		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31396
Q9Z2X1-222-unknown	IVKQAG...	222		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146633
Q9Z2X1-249-unknown	LSDGYG...	249		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34413
Q9Z2X1-249-unknown	LSDGYG...	249		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147693
Q9Z2X1-252-unknown	GYGFTT...	252		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32602
Q9Z2X1-252-unknown	GYGFTT...	252		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147807
Q9Z2X1-308-unknown	FFSPLN...	308		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29456
Q9Z2X1-308-unknown	FFSPLN...	308		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149543
Q9Z2X1-309-unknown	FSPLNP...	309		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31398
Q9Z2X1-309-unknown	FSPLNP...	309		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149564

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RRYIGI	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31396
...RRYIGI	221	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129942
...EEYSGL	248	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34413
...EEYSGL	248	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131046
...SGLSDG	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32602
...SGLSDG	251	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131162
...NDIYNF	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29456
...NDIYNF	307	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132927
...DIYNFF	308	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31398
...DIYNFF	308	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132952
...MGGYD	415	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...MGGYD	415	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72792

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	221	YIGI.\|.IVKQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> HNRPF_MOUSE @221
MMP2_MOUSE	248	YSGL.\|.LSDG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
GRAB_MOUSE	251	LSDG.\|.GYGF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATD_MOUSE	307	IYNF.\|.FFSP	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	308	YNFF.\|.FSPL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> HNRPF_MOUSE @308

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)