Q9JI10: Serine/threonine-protein kinase 3
Protein names | - Serine/threonine-protein kinase 3 - 2.7.11.1 - Mammalian STE20-like protein kinase 2 - MST-2 - STE20-like kinase MST2 - Serine/threonine-protein kinase 3 36kDa subunit - MST2/N - Serine/threonine-protein kinase 3 20kDa subunit - MST2/C |
---|---|
Gene names | Stk3 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9JI10 |
3
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEQPPASKSK LKKLSEDSLT KQPEEVFDVL EKLGEGSYGS VFKAIHKESG QVVAIKQVPV
70 80 90 100 110 120
ESDLQEIIKE ISIMQQCDSP YVVKYYGSYF KNTDLWIVME YCGAGSVSDI IRLRNKTLTE
130 140 150 160 170 180
DEIATILKST LKGLEYLHFM RKIHRDIKAG NILLNTEGHA KLADFGVAGQ LTDTMAKRNT
190 200 210 220 230 240
VIGTPFWMAP EVIQEIGYNC VADIWSLGIT SIEMAEGKPP YADIHPMRAI FMIPTNPPPT
250 260 270 280 290 300
FRKPELWSDD FTDFVKKCLV KSPEQRATAT QLLQHPFIKN AKPVSILRDL IAEAMEIKAK
310 320 330 340 350 360
RHEEQQRELE EEEENSDEDE LDSHTMVKTS SESVGTMRAT STMSEGAQTM IEHNSTMLES
370 380 390 400 410 420
DLGTMVINSE EEEEEEEEEE EDGTMKRNAT SPQVQRPSFM DYFDKQDFKN KSHENCDQSM
430 440 450 460 470 480
REPGPMSNSV FPDNWRVPQD GDFDFLKNLS LEELQMRLKA LDPMMEREIE ELHQRYSAKR
490
QPILDAMDAK KRRQQNF
Isoforms
- Isoform 2 of Serine/threonine-protein kinase 3Sequence View
10 20 30 40 50 60
MEQPPASKSK LKKLSEDSLT KQPEEVFDVL EKLGEGSYGS VFKAIHKESG QVVAIKQVPV
70 80 90 100 110 120
ESDLQEIIKE ISIMQQCDSP YVVKYYGSYF KNTDLWIVME YCGAGSVSDI IRLRNKTLTE
130 140 150 160 170 180
DEIATILKST LKGLEYLHFM RKIHRDIKAG NILLNTEGHA KLADFGVAGQ LTDTMAKRNT
190 200 210 220 230 240
VIGTPFWMAP EVIQEIGYNC VADIWSLGIT SIEMAEGKPP YADIHPMRAI FMIPTNPPPT
250 260 270 280 290 300
FRKPELWSDD FTDFVKKCLV KSPEQRATAT QLLQHPFIKN AKPVSILRDL IAEAMEIKAK
310 320 330 340 350 360
RHEEQQRELE EEEENSDEDE LDSHTMVKTS SESVGTMRAT STMSEGAQTM IEHNSTMLES
370 380 390 400 410 420
DLGTMVINSE EEEEEEEEEE EDGTMKRNAT SPQVQRPSFM DYFDKQDFKN KSHENCDQSM
430 440 450 460 470 480
REPGPMSNSV FPDNWRVPQD GDFDFLKNLS LEELQMRLKA LDPMMEREIE ELHQRYSAKR
490
QPILDAMDAK KRRQQNF
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9JI10-1-Acetylation | MEQPPA... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q9JI10-323-unknown | SHTMVK... | 323 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9JI10-323-unknown | SHTMVK... | 323 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116154 | |||
Q9JI10-362-unknown | LGTMVI... | 362 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32578 | |||
Q9JI10-362-unknown | LGTMVI... | 362 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149632 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EDELDS | 322 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...EDELDS | 322 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt92392 | |||
...MLESDL | 361 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32578 | |||
...MLESDL | 361 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133019 | |||
...RQQNF | 497 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...RQQNF | 497 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86547 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_MOUSE | 361 | ESDL.|.LGTM | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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