Q62448: Eukaryotic translation initiation factor 4 gamma 2

General Information

Protein names	- Eukaryotic translation initiation factor 4 gamma 2 - eIF-4-gamma 2 - eIF-4G 2 - eIF4G 2 - Novel APOBEC-1 target 1 - Translation repressor NAT1 - p97
Gene names	Eif4g2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q62448

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MESAIAEGGA SRFSASSGGG GSRGAPQHYP KTAGNSEFLG KTPGQNAQKW IPARSTRRDD
        70         80         90        100        110        120
NSAANNSANE KERHDAIFRK VRGILNKLTP EKFDKLCLEL LNVGVESKLI LKGVILLIVD
       130        140        150        160        170        180
KALEEPKYSS LYAQLCLRLA EDAPNFDGPA AEGQPGQKQS TTFRRLLISK LQDEFENRTR
       190        200        210        220        230        240
NVDVYDKREN PLLPEEEEQR AIAKIKMLGN IKFIGELGKL DLIHESILHK CIKTLLEKKK
       250        260        270        280        290        300
RVQLKDMGED LECLCQIMRT VGPRLDHERA KSLMDQYFAR MCSLMLSKEL PARIRFLLQD
       310        320        330        340        350        360
TVELREHHWV PRKAFLDNGP KTINQIRQDA VKDLGVFIPA PMAQGRSDFF LEGPFMPPRM
       370        380        390        400        410        420
KMDRDPLGGL ADMFGQMPGS GIGTGPGVIQ DRFSPTMGRH RSNQLFNGHG GHIMPPTQSQ
       430        440        450        460        470        480
FGEMGGKFMK SQGLSQLYHN QSQGLLSQLQ GQSKDMPPRF SKKGQLNADE ISLRPAQSFL
       490        500        510        520        530        540
MNKNQVPKLQ PQITMIPPSA QPPRTQTPPL GQTPQLGLKT NPPLIQEKPA KTSKKPPPSK
       550        560        570        580        590        600
EELLKLTEAV VTDYLNSGNA NDAVSGVREM RAPKHFLPEM LSKVIILSLD RSDEDKEKAS
       610        620        630        640        650        660
SLISLLKQEG IATSDNFMQA FLNVLEQCPK LEVDIPLVKS YLAQFAARAI ISELVSISEL
       670        680        690        700        710        720
AQPLESGTHF PLFLLCLQQL AKLQDREWLT ELFQQSKVNM QKMLPEIDQN KDRMLEILEG
       730        740        750        760        770        780
KGLSFLFPLL KLEKELLKQI KLDPSPQTIY KWIKDNISPK LHVDKGFVNI LMTSFLQYIS
       790        800        810        820        830        840
SEVSPPSDET DSSSAPSKEQ LEQEKQLLLS FKPVMQKFLH DHVDLQVSAL YALQVHCYNS
       850        860        870        880        890        900
SFPKGMLLRF FVHFYDMEII EEEAFLAWKE DITQEFPGKG KALFQVNQWL TWLETAEEEE

SEEEAD

Isoforms

- Isoform 2 of Eukaryotic translation initiation factor 4 gamma 2

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q62448-1-unknown	MESAIA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77559
Q62448-1-Acetylation	MESAIA...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q62448-1-Acetylation	MESAIA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108595
Q62448-330-unknown	AVKDLG...	330		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32462
Q62448-330-unknown	AVKDLG...	330		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150539
Q62448-375-unknown	GQMPGS...	375		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30557
Q62448-375-unknown	GQMPGS...	375		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151505

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QIRQDA	329	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32462
...QIRQDA	329	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133935
...LADMFG	374	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30557
...LADMFG	374	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134909
...EEEAD	906	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EEEAD	906	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73177

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	329	RQDA.\|.AVKD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATE_MOUSE	374	DMFG.\|.GQMP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> IF4G2_MOUSE @374

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)