Q6IRU5: Clathrin light chain B

General Information

Protein names	- Clathrin light chain B - Lcb
Gene names	Cltb
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6IRU5

7 N-termini

8 C-termini

6 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Clathrin light chain B - Isoform 3 of Clathrin light chain B

Sequence View

        10         20         30         40         50         60
MAEDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DPGFGAPAAS QVASAQPGLA
        70         80         90        100        110        120
SGAGSEDMST TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ KKRLQELDAA
       130        140        150        160        170        180
SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRIADKA FYQQPDADTI GYVASEEAFV
       190        200        210        220
KESKEETPGT EWEKVAQLCD FNPKSSKQCK DVSRLRSVLM SLKQTPLSR         10         20         30         40         50         60
MAEDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DPGFGAPAAS QVASAQPGLA
        70         80         90        100        110        120
SGAGSEDMST TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ KKRLQELDAA
       130        140        150        160        170        180
SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRIADKA FYQQPDADTI GYVASEEAFV
       190        200        210        220
KESKEETPGT EWEKVAQLCD FNPKSSKQCK DVSRLRSVLM SLKQTPLSR

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 8 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6IRU5-1-unknown	MAEDFG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6IRU5-1-unknown	MAEDFG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70909
Q6IRU5-1-unknown	MAEDFG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70910
Q6IRU5-76-unknown	VFQEAN...	76	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32467
Q6IRU5-76-unknown	VFQEAN...	76	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141070
Q6IRU5-76-unknown	VFQEAN...	76	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141071
Q6IRU5-78-unknown	QEANGP...	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30599
Q6IRU5-78-unknown	QEANGP...	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141185
Q6IRU5-78-unknown	QEANGP...	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141187
Q6IRU5-88-unknown	AAIAQA...	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30602
Q6IRU5-88-unknown	AAIAQA...	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141726
Q6IRU5-88-unknown	AAIAQA...	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141727
Q6IRU5-147-unknown	VEKNKI...	147	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30605
Q6IRU5-200-unknown	DFNPKS...	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29198
Q6IRU5-200-unknown	DFNPKS...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145954
Q6IRU5-220-unknown	MSLKQT...	220	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30606
Q6IRU5-220-unknown	MSLKQT...	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146632

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TVNGDV	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32467
...TVNGDV	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124222
...TVNGDV	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124223
...NGDVFQ	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30599
...NGDVFQ	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124343
...NGDVFQ	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124345
...PADGYA	87	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30602
...PADGYA	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124908
...PADGYA	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124909
...RQSEQV	146	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30605
...RQSEQV	146	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154919
...RQSEQV	146	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154920
...KINNRI	155	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66528
...KINNRI	155	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91724
...VAQLCD	199	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29198
...VAQLCD	199	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129251
...LRSVLM	219	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30606
...LRSVLM	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129941
...TPLSR	229	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TPLSR	229	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66527

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	75	NGDV.\|.VFQE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATE_MOUSE	77	DVFQ.\|.QEAN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CLCB_MOUSE @77
CATE_MOUSE	87	DGYA.\|.AAIA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CLCB_MOUSE @87
CATE_MOUSE	146	SEQV.\|.VEKN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CLCB_MOUSE @146
CATD_MOUSE	199	QLCD.\|.DFNP	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> CLCB_MOUSE @199
CATE_MOUSE	219	SVLM.\|.MSLK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CLCB_MOUSE @219

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)