P70236: Dual specificity mitogen-activated protein kinase kinase 6
Protein names | - Dual specificity mitogen-activated protein kinase kinase 6 - MAP kinase kinase 6 - MAPKK 6 - 2.7.12.2 - MAPK/ERK kinase 6 - MEK 6 - SAPKK3 |
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Gene names | Map2k6 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P70236 |
2
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIVELG
70 80 90 100 110 120
RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DVSMRTVDCP FTVTFYGALF
130 140 150 160 170 180
REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV
190 200 210 220 230 240
KPSNVLINTL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI
250 260 270 280 290 300
WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSADFVDF TSQCLKKNSK
310 320 330
ERPTYPELMQ HPFFTVHESK AADVASFVKL ILGD
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P70236-1-unknown | MSQSKG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P70236-52-unknown | DLEPIV... | 52 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32390 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EVKADD | 51 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32390 | |||
...DFTSQC | 293 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000097831 | |||
...LILGD | 334 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_MOUSE | 51 | KADD.|.DLEP | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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