Q3UMU9: Hepatoma-derived growth factor-related protein 2

General Information

Protein names	- Hepatoma-derived growth factor-related protein 2 - HRP-2
Gene names	Hdgfrp2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3UMU9

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Hepatoma-derived growth factor-related protein 2 - Isoform 3 of Hepatoma-derived growth factor-related protein 2 - Isoform 4 of Hepatoma-derived growth factor-related protein 2

Sequence View

        10         20         30         40         50         60
MPHAFKPGDL VFAKMKGYPH WPARIDDIAD GAVKPPPNKY PIFFFGTHET AFLGPKDLFP
        70         80         90        100        110        120
YDKCKDKYGK PNKRKGFNEG LWEIQNNPHA SYSAPPPVSS SDSEAPEADL GCGSDVDKDK
       130        140        150        160        170        180
ESRRVMTVTA VTTTATSDRM ESDSDSDKSS DHSGLKRKTP VLKVSVSKRA RRASSDLDQA
       190        200        210        220        230        240
SVSPSEEDSE SPSESEKTSD QDFTPEKKTA ARPPRRGPLG GRKKKKVPSA SDSDSKADSD
       250        260        270        280        290        300
GAKEEPVVTA QPSPSSSSSS SSSSSSDSDV SVKKPPRGRK PAEKPPPKPR GRRPKPERPP
       310        320        330        340        350        360
STSSSDSDSD SGEVDRISEW KRRDEERRRE LEARRRREQE EELRRLREQE REEKERRKER
       370        380        390        400        410        420
AERGGSSGEE LEDEEPVKKR SRKARGRGTP SSSDSEPEGE LGKEGKKLAK KSQLPGSESA
       430        440        450        460        470        480
RKPGQKEKRG RPDEKPRARP VKVERTRKRS EGLSLERKGE KKKEPSVEER LQKLHSEIKF
       490        500        510        520        530        540
ALKVDNPDVR KCLSALEELG TLQVTSQILQ KNTDVVATLK KIRRYKANKD VMAKAAEVYT
       550        560        570        580        590        600
RLKSRVLGPK VEALQKVNKA GAEKERADNE KLEEQPGEQA PRELAEDEPS TDRSAPVNGE
       610        620        630        640        650        660
ATSQKGENME DRAQEDGQDS EDGPRGGSSE ELHDSPRDNS DPAKPGNERQ DHERTRLASE

SANDDNEDS         10         20         30         40         50         60
MPHAFKPGDL VFAKMKGYPH WPARIDDIAD GAVKPPPNKY PIFFFGTHET AFLGPKDLFP
        70         80         90        100        110        120
YDKCKDKYGK PNKRKGFNEG LWEIQNNPHA SYSAPPPVSS SDSEAPEADL GCGSDVDKDK
       130        140        150        160        170        180
ESRRVMTVTA VTTTATSDRM ESDSDSDKSS DHSGLKRKTP VLKVSVSKRA RRASSDLDQA
       190        200        210        220        230        240
SVSPSEEDSE SPSESEKTSD QDFTPEKKTA ARPPRRGPLG GRKKKKVPSA SDSDSKADSD
       250        260        270        280        290        300
GAKEEPVVTA QPSPSSSSSS SSSSSSDSDV SVKKPPRGRK PAEKPPPKPR GRRPKPERPP
       310        320        330        340        350        360
STSSSDSDSD SGEVDRISEW KRRDEERRRE LEARRRREQE EELRRLREQE REEKERRKER
       370        380        390        400        410        420
AERGGSSGEE LEDEEPVKKR SRKARGRGTP SSSDSEPEGE LGKEGKKLAK KSQLPGSESA
       430        440        450        460        470        480
RKPGQKEKRG RPDEKPRARP VKVERTRKRS EGLSLERKGE KKKEPSVEER LQKLHSEIKF
       490        500        510        520        530        540
ALKVDNPDVR KCLSALEELG TLQVTSQILQ KNTDVVATLK KIRRYKANKD VMAKAAEVYT
       550        560        570        580        590        600
RLKSRVLGPK VEALQKVNKA GAEKERADNE KLEEQPGEQA PRELAEDEPS TDRSAPVNGE
       610        620        630        640        650        660
ATSQKGENME DRAQEDGQDS EDGPRGGSSE ELHDSPRDNS DPAKPGNERQ DHERTRLASE

SANDDNEDS         10         20         30         40         50         60
MPHAFKPGDL VFAKMKGYPH WPARIDDIAD GAVKPPPNKY PIFFFGTHET AFLGPKDLFP
        70         80         90        100        110        120
YDKCKDKYGK PNKRKGFNEG LWEIQNNPHA SYSAPPPVSS SDSEAPEADL GCGSDVDKDK
       130        140        150        160        170        180
ESRRVMTVTA VTTTATSDRM ESDSDSDKSS DHSGLKRKTP VLKVSVSKRA RRASSDLDQA
       190        200        210        220        230        240
SVSPSEEDSE SPSESEKTSD QDFTPEKKTA ARPPRRGPLG GRKKKKVPSA SDSDSKADSD
       250        260        270        280        290        300
GAKEEPVVTA QPSPSSSSSS SSSSSSDSDV SVKKPPRGRK PAEKPPPKPR GRRPKPERPP
       310        320        330        340        350        360
STSSSDSDSD SGEVDRISEW KRRDEERRRE LEARRRREQE EELRRLREQE REEKERRKER
       370        380        390        400        410        420
AERGGSSGEE LEDEEPVKKR SRKARGRGTP SSSDSEPEGE LGKEGKKLAK KSQLPGSESA
       430        440        450        460        470        480
RKPGQKEKRG RPDEKPRARP VKVERTRKRS EGLSLERKGE KKKEPSVEER LQKLHSEIKF
       490        500        510        520        530        540
ALKVDNPDVR KCLSALEELG TLQVTSQILQ KNTDVVATLK KIRRYKANKD VMAKAAEVYT
       550        560        570        580        590        600
RLKSRVLGPK VEALQKVNKA GAEKERADNE KLEEQPGEQA PRELAEDEPS TDRSAPVNGE
       610        620        630        640        650        660
ATSQKGENME DRAQEDGQDS EDGPRGGSSE ELHDSPRDNS DPAKPGNERQ DHERTRLASE

SANDDNEDS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q3UMU9-1-unknown	MPHAFK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3UMU9-1-unknown	MPHAFK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76845
Q3UMU9-1-unknown	MPHAFK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76846
Q3UMU9-1-unknown	MPHAFK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76847
Q3UMU9-15-unknown	MKGYPH...	15	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q3UMU9-15-unknown	MKGYPH...	15	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195025
Q3UMU9-15-unknown	MKGYPH...	15	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195026
Q3UMU9-15-unknown	MKGYPH...	15	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195027
Q3UMU9-110-unknown	LGCGSD...	110	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32437
Q3UMU9-110-unknown	LGCGSD...	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142955
Q3UMU9-110-unknown	LGCGSD...	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142956

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...APEADL	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32437
...APEADL	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126167
...APEADL	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126168
...DNEDS	669	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DNEDS	669	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72465
...DNEDS	669	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72463
...DNEDS	669	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72464

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	109	EADL.\|.LGCG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)