Q9CY58: Plasminogen activator inhibitor 1 RNA-binding protein

General Information

Protein names	- Plasminogen activator inhibitor 1 RNA-binding protein - PAI1 RNA-binding protein 1 - PAI-RBP1 - SERPINE1 mRNA-binding protein 1
Gene names	Serbp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9CY58

7 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Plasminogen activator inhibitor 1 RNA-binding protein - Isoform 3 of Plasminogen activator inhibitor 1 RNA-binding protein - Isoform 4 of Plasminogen activator inhibitor 1 RNA-binding protein

Sequence View

        10         20         30         40         50         60
MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG AKSAAQAAAQ
        70         80         90        100        110        120
TNSNAAGKQL RKESQKDRKN PLPPSVGVAD KKEETQPPVA LKKEGIRRVG RRPDQQLQGD
       130        140        150        160        170        180
GKLIDRRAER RPPRERRFEK PLEEKGEGGE FSVDRPIIER PIRGRGGLGR GRGGRGRGMG
       190        200        210        220        230        240
RGDGFDSRGK REFDRHSGSD RSSFSHYSGL KHEDKRGGSG SHNWGTVKDE LTESPKYIQK
       250        260        270        280        290        300
QISYNCSDLD QSNVTEETPE GEEHPVADTE NKENEVEEVK EEGPKEMTLD EWKAIQNKDR
       310        320        330        340        350        360
AKVEFNIRKP NEGADGQWKK GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD
       370        380        390        400
LGRPGRGGRG GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA         10         20         30         40         50         60
MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG AKSAAQAAAQ
        70         80         90        100        110        120
TNSNAAGKQL RKESQKDRKN PLPPSVGVAD KKEETQPPVA LKKEGIRRVG RRPDQQLQGD
       130        140        150        160        170        180
GKLIDRRAER RPPRERRFEK PLEEKGEGGE FSVDRPIIER PIRGRGGLGR GRGGRGRGMG
       190        200        210        220        230        240
RGDGFDSRGK REFDRHSGSD RSSFSHYSGL KHEDKRGGSG SHNWGTVKDE LTESPKYIQK
       250        260        270        280        290        300
QISYNCSDLD QSNVTEETPE GEEHPVADTE NKENEVEEVK EEGPKEMTLD EWKAIQNKDR
       310        320        330        340        350        360
AKVEFNIRKP NEGADGQWKK GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD
       370        380        390        400
LGRPGRGGRG GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA         10         20         30         40         50         60
MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG AKSAAQAAAQ
        70         80         90        100        110        120
TNSNAAGKQL RKESQKDRKN PLPPSVGVAD KKEETQPPVA LKKEGIRRVG RRPDQQLQGD
       130        140        150        160        170        180
GKLIDRRAER RPPRERRFEK PLEEKGEGGE FSVDRPIIER PIRGRGGLGR GRGGRGRGMG
       190        200        210        220        230        240
RGDGFDSRGK REFDRHSGSD RSSFSHYSGL KHEDKRGGSG SHNWGTVKDE LTESPKYIQK
       250        260        270        280        290        300
QISYNCSDLD QSNVTEETPE GEEHPVADTE NKENEVEEVK EEGPKEMTLD EWKAIQNKDR
       310        320        330        340        350        360
AKVEFNIRKP NEGADGQWKK GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD
       370        380        390        400
LGRPGRGGRG GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9CY58-1-unknown	MPGHLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84170
Q9CY58-1-unknown	MPGHLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84171
Q9CY58-1-unknown	MPGHLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84172
Q9CY58-1-unknown	MPGHLQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9CY58-2-unknown	PGHLQE...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9CY58-2-unknown	PGHLQE...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9CY58-2-unknown	PGHLQE...	2		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q9CY58-2-unknown	PGHLQE...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110781
Q9CY58-2-unknown	PGHLQE...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110782
Q9CY58-2-unknown	PGHLQE...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110783
Q9CY58-4-unknown	HLQEGF...	4		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q9CY58-4-unknown	HLQEGF...	4	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160566
Q9CY58-4-unknown	HLQEGF...	4	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160567
Q9CY58-4-unknown	HLQEGF...	4	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160568
Q9CY58-60-unknown	QTNSNA...	60	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34220
Q9CY58-60-unknown	QTNSNA...	60	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139938
Q9CY58-60-unknown	QTNSNA...	60	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139939
Q9CY58-60-unknown	QTNSNA...	60	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139940
Q9CY58-121-unknown	GKLIDR...	121	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32557
Q9CY58-121-unknown	GKLIDR...	121	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143509
Q9CY58-121-unknown	GKLIDR...	121	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143510
Q9CY58-121-unknown	GKLIDR...	121	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143511
Q9CY58-207-unknown	YSGLKH...	207	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34224
Q9CY58-207-unknown	YSGLKH...	207	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146800
Q9CY58-207-unknown	YSGLKH...	207	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146801
Q9CY58-334-unknown	AEDSVM...	334		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q9CY58-334-unknown	AEDSVM...	334	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160534
Q9CY58-334-unknown	AEDSVM...	334	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160535

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AQAAAQ	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34220
...AQAAAQ	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123043
...AQAAAQ	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123044
...AQAAAQ	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123045
...QLQGDG	120	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32557
...QLQGDG	120	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126749
...QLQGDG	120	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126750
...QLQGDG	120	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126751
...SSFSHY	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34224
...SSFSHY	206	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130123
...SSFSHY	206	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130124
...FPALA	407	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FPALA	407	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79789
...FPALA	407	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79788

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	59	AAAQ.\|.QTNS	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
GRAB_MOUSE	120	QGDG.\|.GKLI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MMP2_MOUSE	206	FSHY.\|.YSGL	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)